Kişi: BİCAN DEMİR, AYLİN
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Yayın Sadece Metadata A rare cause of epilepsy: Ulegyria revisited in a series of 10 patients(Sage Publications, 2021-09-17) Demir, Aylin Bican; Eser, Pınar; Bekar, Ahmet; Hakyemez, Bahattin; Bora, İbrahim; BİCAN DEMİR, AYLİN; Eser, Pınar; BEKAR, AHMET; HAKYEMEZ, BAHATTİN; BORA, İBRAHİM HAKKI; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı/Epilepsi Merkezi.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Beyin Cerrahi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0001-6739-8605; 0000-0003-0132-9927; 0000-0002-3425-0740; ABX-9081-2022; AAI-2073-2021; V-7170-2017; AAI-2318-2021; ENI-7759-2022Introduction. Ulegyria results from perinatal hypoxic-ischemic brain injury in term infants. The specific mushroom-shaped configuration of ulegyria results from small atrophic circumvolutions at the bottom of a sulcus underlying an intact gyral apex. Clinically, ulegyria is generally associated with epilepsy. Here, we aimed to delineate the characteristics of patients with ulegyria and the epileptic seizures they experience. Material and methods. Medical records including radiology and pathology reports, video-electroencephalographic (EEG) analysis, operative notes, hospital progress and outpatient clinic notes were reviewed retrospectively in a total of 10 ulegyria patients. Results. Patients ages ranged between 24 and 58 years (mean, 32 +/- 9.8 years). Past medical history was confirmed for neonatal asphyxia in 2 (20%). Neurological examination was remarkable for spastic hemiparesis in 1 (10%) patient with perisylvian ulegyria and for visual field deficits in 2 patients (20%) with occipital ulegyria. Ulegyria most commonly involved the temporoparietal region (n = 5, 50%) followed by the perisylvian area (n = 2, 20%). Except the one with bilateral perisylvian ulegyria, all patients had unilateral lesions (n = 9, 90%). Hippocampal sclerosis accompanied ulegyria in 2 patients (20%). All patients experienced epileptic seizures. Mean age at seizure onset was 8.8 +/- 5.4 years (range, 2-20 years). Interictal scalp EEG and EEG-video monitoring records demonstrated temporoparietal and frontotemporal activities in 5 (50%) and 2 (20%) patients, respectively. The seizures were successfully controlled by antiepileptic medication in 8 patients (n = 8, 80%). The remaining 2 patients (%20) with concomitant hippocampal sclerosis required microsurgical resection of the seizure foci due to medically resistant seizures. Discussion. Ulegyria is easily recognized with its unique magnetic resonance imaging characteristics and clinical presentation in the majority of cases. It is highly associated with either medically resistant or medically controllable epileptic seizures. The treatment strategy depends on the age at onset and extends of the lesion that has a significant impact on the severity of the clinical picture.Yayın Sadece Metadata Investigating the impact of sleep stage of the patients at which they wake up on the stanford sleepiness scale after polysomnography(Galenos, 2022-06-01) Demir, Aylin Bican; Leba, Leyla Köse; Uslu, Pınar Uzun; Demir, Aylin Bican; BİCAN DEMİR, AYLİN; 0000-0001-6739-8605; V-7170-2017Objective: Sleep inertia is a period that cognitive performance and wakefulness are lower in the transition phase from sleep to wakefulness than during the daytime. The sleep inertia period is reported to extend from 1 minute to 4 hours. In our study, we aimed to investigate the impact of the sleep stage of the patients at which they wake up on the sleep inertia and the Stanford sleepiness scale (SSS) as well.Materials and Methods: Patients who applied to Bursa Uludag University Faculty of Medicine, Department of Neurology between the dates of March and September 2016, with such complaints about sleep disorders and with indications for admission to polysomnography were involved in the study. The patients were informed and their consent was received after PSG to complete the SSS.Results: One hundred patients were involved in the study. There were 55 patients waken up in the 2nd stage of NREM, 35 patients in REM sleep, and 10 patients in the 3rd stage of NREM. The points given by the patients and the number of these patients were as follows: 1-3 points for 37, 28, and 8 patients; 4 points for 1, 1, and 1 patient; and 5-7 points for 17, 6, and 1 patient, respectively.Conclusion: The arousal threshold differs in REM sleep and at the 1st, 2nd, and 3rd stages of NREM. The impact of waking up at any stages on the sleep inertia and/or the performance of the patients during the day is not known. For this reason, revealing the impacts of waking up at different sleep stages on the SSS was aimed in this study.Yayın Sadece Metadata The assessment of brain evoked potentials in patients with caps(Springer, 2021-04-01) Çekiç, Şükrü; Demir, Aylin Bican; Kılıç, Sara; ÇEKİÇ, ŞÜKRÜ; BİCAN DEMİR, AYLİN; KILIÇ GÜLTEKİN, SARA ŞEBNEM; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Uludağ Üniversitesi Çocuk Alerji ve İmmünoloji bilim Dalı; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı; 0000-0002-9574-1842; 0000-0001-6739-8605; L-1933-2017; KHB-9765-2024; IDK-5744-2023