Person: COŞKUN, BURHAN
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COŞKUN
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BURHAN
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Publication Investigation of infectious droplet dispersion in a hospital examination room cooled by split-type air conditioner(Springer, 2024-05-08) Yüce, Bahadir Erman; Kalay, Onur Can; Karpat, Fatih; Alemdar, Adem; Temel, Şehime Gülsün; Dilektaşlı, Aslı Görek; Başkan, Emel Bülbül; Özakın, Cüneyt; Coşkun, Burhan; YÜCE, BAHADIR ERMAN; Kalay, Onur Can; KARPAT, FATİH; ALEMDAR, ADEM; TEMEL, ŞEHİME GÜLSÜN; GÖREK DİLEKTAŞLI, ASLI; BÜLBÜL BAŞKAN, EMEL; ÖZAKIN, CÜNEYT; COŞKUN, BURHAN; Tıp Fakültesi; Histoloji ve Embriyoloji Ana Bilim DalıThe novel coronavirus (SARS-CoV-2) outbreak has spread worldwide, and the World Health Organization (WHO) declared a global pandemic in March 2020. The transmission mechanism of SARS-CoV-2 in indoor environments has begun to be investigated in all aspects. In this regard, many numerical studies on social distancing and the protection of surgical masks against infection risk have neglected the evaporation of the particles. Meanwhile, a 1.83 m (6 feet) social distancing rule has been recommended to reduce the infection risk. However, it should be noted that most of the studies were conducted in static air conditions. Air movement in indoor environments is chaotic, and it is not easy to track all droplets in a ventilated room experimentally. Computational Fluid Dynamics (CFD) enables the tracking of all particles in a ventilated environment. This study numerically investigated the airborne transmission of infectious droplets in a hospital examination room cooled by a split-type air conditioner with the CFD method. Different inlet velocities (1, 2, 3 m/s) were considered and investigated separately. Besides, the hospital examination room is a model of one of the Bursa Uludag University Hospital examination rooms. The patient, doctor, and some furniture are modeled in the room. Particle diameters considered ranged from 2 to 2000 mu m. The evaporation of the droplets is not neglected, and the predictions of particle tracks are shown. As a result, locations with a high infection risk were identified, and the findings that could guide the design/redesign of the hospital examination rooms were evaluated.Publication The role of educational level and cognitive status in men undergoing artificial urinary sphincter implantation(Elsevier Science, 2021-01-01) Keleş, Ahmet; Onur, Rahmi; Aydos, Murat; Dinçer, Murat; Koca, Orhan; Coşkun, Burhan; İmamoğlu, Abdurrahim; Karakeçi, Ahmet; COŞKUN, BURHAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; AAH-9704-2021 ; JCO-5169-2023OBJECTIVE To examine the relationship between education level, cognitive function of patients and the success/ revision rates of artificial urinary sphincter (AUS) implantation in men with postprostatectomy incontinence.METHODS Between January 2010 and March 2018, 163 patients (mean age, 68 +/- 6.8 years) with moderate-to-severe stress urinary incontinence who underwent AUS implantation were retrospectively examined. Demographic data, body mass index, comorbidities, surgical technique, previous strictures, and radiation therapy were recorded. Incontinence was measured by daily pad use and evaluated by International Consultation on Incontinence Questionnaire-short form. Patients' overall improvement was assessed using the Patient Global Impression of Improvement questionnaire. Education level was determined using the International Standard Classification of Education. Cognitive status was assessed using the Mini-Mental State Examination. Treatment success was defined as the need for <= 1 pad/day at last follow-up.RESULTS AUS was successful in 77.3% of patients. The International Consultation on Incontinence Questionnaire-short form score improved significantly from 19.9 +/- 2.9 to 4.4 +/- 5.4 (P = .001). The median outcome reported subjectively on the Patient Global Impression of Improvement scale was 2.1 +/- 1.5 (1-7) and self-reported as "much better." Patients' education level had statistically no significant relationship with AUS success and revision rates. Similarly, there was no significant relationship between cognitive status, educational level and the need for revision of AUS (P >.05). However, patients with moderate cognitive impairment and a body mass index >30 showed significantly lower AUS success rates (P <.05).CONCLUSION AUS implantation is safe and effective treatment option especially for nonobese and cognitively intact patients of all educational levels. (C) 2020 Elsevier Inc.Publication Robotic surgery in radical cystectomy(Galenos Yayıncılık, 2013-03-01) Kordan, Yakup; Coşkun, Burhan; Kordan, Yakup; COŞKUN, BURHAN; Tip Fakültesi; Üroloji Ana Bilim Dalı; 0000-0002-9947-848X; 0000-0002-8242-9921; AAH-9704-2021; JCO-5169-2023Recently, there is an increasing interest and wide spreading use on robot assisted surgeries. In this review, we aimed to discuss perioperative and oncological results of the robot assisted radical cystectomy. Several advantages like reduced blood loss, less analgesic requirement and better cosmetic results were achieved with robot assisted radical cystectomy. Although short and medium term oncological results are comparable with the open series; long-term oncological results are still awaited.Publication Factors influencing lymphocel development after kidney transplantation: Single center experience(Oxford University Press, 2015-05-01) Sayılar, Emel Işıktaş; Ersoy, Alparslan; Ayar, Yavuz; Aydın, Mehmet Fethullah; Şahin, Ahmet Bilgehan; Coşkun, Burhan; Kaygısız, Onur; Yıldız, Abdulmecit; Kordan, Yakup; Vuruşkan, Hakan; SAYILAR, EMEL IŞIKTAŞ; ERSOY, ALPARSLAN; AYAR, YAVUZ; AYDIN, MEHMET FETHULLAH; ŞAHİN, AHMET BİLGEHAN; COŞKUN, BURHAN; KAYGISIZ, ONUR; YILDIZ, ABDULMECİT; KORDAN, YAKUP; VURUŞKAN, HAKAN; 0000-0003-4607-9220; 0000-0002-5665-7402; 0000-0002-7846-0870; 0000-0002-8242-9921; 0000-0002-9790-7295; 0000-0002-9947-848X; 0000-0002-0710-0923; AAH-5054-2021; O-9948-2015; L-9439-2019; JCO-5169-2023; AAH-9704-2021; AGF-0767-2022; AAJ-8220-2020; AAM-4927-2020; GSE-0029-2022; W-2575-2017; AAM-9726-2020; HIG-9032-2022; GAF-0095-2022; EFH-9523-2022Publication Prognostic value of estrogen receptors in patients who underwent prostatectomy for non-metastatic prostate cancer(Spandidos Publ Ltd, 2023-02-01) Aydın, Yavuz Mert; Şahin, Ahmet Bilgehan; Dölek, Rabia; Vuruşkan, Berna Aytaç; Ocakoğlu, Gökhan; Vuruşkan, Hakan; Yavaşçaoğlu, İsmet; Coşkun, Burhan; AYDIN, YAVUZ MERT; ŞAHİN, AHMET BİLGEHAN; DÖLEK, RABİA; AYTAÇ VURUŞKAN, BERNA; OCAKOĞLU, GÖKHAN; VURUŞKAN, HAKAN; YAVAŞCAOĞLU, İSMET; COŞKUN, BURHAN; Tıp Fakültesi; Tıbbi Onkoloji Ana Bilim Dalı; 0000-0002-6287-6767; 0000-0002-7846-0870; 0000-0002-1114-6051; 0000-0002-8242-9921; AAH-9704-2021; AFP-3055-2022; HSH-9815-2023; JCO-5169-2023; AAH-5180-2021; AAM-4927-2020; EEJ-1452-2022; EFH-9523-2022; EIN-0828-2022Estrogen receptors in prostate cancer (PCa) are a subject of debate. The aim of the present study was to investigate whether estrogen receptor-alpha (ER alpha) and estrogen receptor-beta (ER beta) impact the biochemical recurrence (BCR) of non-metastatic PCa after surgery. Following the application of the exclusion criteria, data from 108 patients who underwent laparoscopic radical prostatectomy between January 2011 and December 2019 were retrospectively evaluated. A total of 36 patients with BCR constituted the BCR group. The control group was formed using the Propensity Score Matching (PSM) method with a 1:2 ratio, including parameters with well-studied effects on BCR. The median follow-up time was 74.3 (range, 30-127.5) months in the BCR group and 66.6 (range, 31.5-130) months in the control group. Pathology specimens from the two groups were immunohistochemically stained with ER alpha and ER beta antibodies. Logistic regression analysis and survival analysis were performed. No differences in clinicopathological characteristics were detected between the two groups. The patients with ER alpha(-)/ER beta(+) staining results had a significantly fewer BCRs than other patients (P=0.024). In the logistic regression analysis, patients with ER alpha(-)/ER beta(+) PCa also had a significantly lower risk of recurrence (P=0.048). In the survival analysis, the 5-year BCR-free survival rate of patients with ER alpha(-)/ER beta(+) PCa was higher than that of other patients (85.7 vs. 66.1%; P=0.031). Excluding the effects of well-studied risk factors for recurrence by the PSM method, the present study showed that ER alpha and ER beta have prognostic value for non-metastatic PCa. The 5-year BCR-free survival rate is significantly higher in patients whose PCa tissue has ER alpha(-)/ER beta(+) staining results.Publication The predictive factors that total laser energy consumed during retrograde intrarenal surgery (RIRS): stone area and density(Springer London Ltd, 2023-05-26) Kaygısız, Onur; Aydın, Yavuz Mert; Çiçek, Mehmet Çağatay; Polat, Rıdvan; Coşkun, Burhan; Ocakoğlu, Gökhan; Kılıçarslan, Hakan; KAYGISIZ, ONUR; AYDIN, YAVUZ MERT; ÇİÇEK, MEHMET ÇAĞATAY; POLAT, RIDVAN; COŞKUN, BURHAN; OCAKOĞLU, GÖKHAN; KILIÇARSLAN, HAKAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0002-9790-7295; 0000-0002-6287-6767; 0000-0002-0471-5404; 0000-0003-0261-3671; 0000-0002-8242-9921; 0000-0002-1114-6051; AFP-3055-2022; AAH-5180-2021; L-9439-2019; JCO-5169-2023; AAH-9704-2021; HGM-5995-2022; JIT-9412-2023Holmium: YAG (Ho: YAG) laser lithotripsy with flexible ureterorenoscopy can be used with high stone-free and low complication rates for renal stones. This study aimed to determine the factors affecting the total laser energy in cases with provided stone-free status after a single session of retrograde intrarenal surgery (RIRS). Data of 222 patients who underwent RIRS between October 2017 and March 2020 were evaluated retrospectively. After exclusion criteria, the study was carried out with 184 stone-free cases. All cases were performed without using a ureteral access sheath (UAS), and dusting was preferred as the lithotripsy method. The effects of age, gender, body mass index (BMI), previous RIRS history, previous shock wave lithotripsy (SWL) history, stone localization, number of stones, stone surface area, and stone density on total laser energy were analyzed. There was no significant correlation between total laser energy with gender, BMI, previous RIRS history, previous SWL history, stone localization, and the number of stones (p:0.347, p:0.482, p:0.119, p:0.167, p:0.907, p:0.933 respectively). There was a significant correlation between age and total laser energy (p = 0.032), but it was not observed when the effect of the stone surface area was removed (p = 0.354). There were significant correlations between total laser energy and stone surface area, stone density, and total laser time (p<0.001, p<0.001, and p <0.001, respectively). Stone area and stone density affect the total energy consumed during laser lithotripsy. Urologists should consider the stone area, stone density, and the power of the laser device to determine which surgical technic to prefer.Publication Comparison of ureteroscopic laser lithotripsy with laparoscopic ureterolithotomy for large proximal and mid-ureter stones(Karger, 2015-01-01) Kaygısız, Onur; Coşkun, Burhan; Kılıçarslan, Hakan; Kordan, Yakup; Vuruşkan, Hakan; Özmerdiven, Gökhun; Yavacaoğlu, İsmet; KAYGISIZ, ONUR; COŞKUN, BURHAN; KILIÇARSLAN, HAKAN; Kordan, Yakup; VURUŞKAN, HAKAN; Özmerdiven, Gökhun; Yavacaoğlu, İsmet; Tıp Fakültesi; Üroloji Bölümü; 0000-0002-9790-7295; 0000-0002-8242-9921; 0000-0002-9947-848X; AAH-9704-2021; L-9439-2019; JCO-5169-2023; AAM-9726-2020; JIT-9412-2023; GAF-0095-2022; EFH-9523-2022; JIF-9579-2023; EIN-0828-2022Objectives: To compare the effectiveness and complications of ureteroscopic laser lithotripsy with laparoscopic ureter laparoscopic ureterolithotomy in mid- or proximal portion of large ureteral stones. Material and Methods: We reviewed patients with large (>15 mm) ureteral stone and those who underwent ureteroscopic laser lithotripsy CURS group) or laparoscopic ureterolithotomy (LU group). The first attempt was considered successful in patients who had residual fragments smaller than 2 mm and no conversion of the primary procedure to another. Results: Sixty patients (URS group 29, LU group 31) met inclusion criteria. FURS was used as an adjunctive procedure in one patient for URS group and in two patients for LU group in the same season. LU had a higher success rate and the first-day stone-free rate when compared with URS. Number of procedures was also significantly higher in URS group. There was no difference in stone-free rates at the first and third months, and length of hospitalization and operation were higher in the LU group. Only two patients in the LU group and one patient in the URS group had major complications. Conclusions: Laparoscopy is an effective option of large proximal and mid-ureter stone treatment; however, URS provides similar stone-free rates at three months as a minimal invasive procedure.Publication The relationship between surgical complications and graft outcomes after kidney transplantation(Wiley, 2019-10-01) Düger, Hakan; Ersoy, Alparslan; Dizdar, Oğuzhan Sıtkı; Yıldız, Abdulmecit; Oruç Ayşegül; Ünsal, Oktay; Akgür, Suat; Kordan, Yakup; Kaygısız, Onur; Coşkun, Burhan; Vuruskan, Hakan; Düger, Hakan; ERSOY, ALPARSLAN; Dizdar, Oğuzhan Sıtkı; YILDIZ, ABDULMECİT; ORUÇ, AYŞEGÜL; Ünsal, Oktay; AKGÜR, SUAT; Kordan, Yakup; KAYGISIZ, ONUR; COŞKUN, BURHAN; VURUŞKAN, HAKAN; Tıp Fakültesi; Nefroloji Bölümü; 0000-0001-5478-3192; 0000-0002-0342-9692; 0000-0002-9947-848X; 0000-0002-9790-7295; 0000-0002-8242-9921; AAM-9726-2020; AAH-5054-2021; AAH-4002-2021; AAH-9704-2021; IZP-9361-2023; JCO-5169-2023; L-9439-2019; D-6213-2013; GPK-6118-2022Publication Evaluation of incidence and histolopathological findings of soft tissue sarcomas in genitourinary tract: Uludag University experience(Brazilian Soc Urol, 2019-01-01) Vuruşkan, Berna Aytaç; Özşen, Mine; Coşkun, Burhan; Yalçınkaya, Ülviye; AYTAÇ VURUŞKAN, BERNA; ÖZŞEN, MİNE; COŞKUN, BURHAN; YALÇINKAYA, ÜLVİYE; Tıp Fakültesi; Cerrahi Patoloji Ana Bilim Dalı; 0000-0002-5771-7649; 0000-0002-8242-9921; AAI-1609-2021; JCO-5169-2023; AAH-8924-2021; AAH-9746-2021; AAH-9704-2021Purpose: In this study we aimed to review urological soft tissue sarcomas of genitourinary tract that were diagnosed in our institution and their prognostic factors for survival.Materials and Methods: The clinical and pathological records of 31 patients who had diagnosis of soft tissue sarcomas primarily originating from the genitourinary tract between 2005-2011 were reviewed.Results: The most common site was kidney (17 cases, 54.8%), and most common diagnosis was leiomyosarcoma (11 cases, 35.4%). A total of 24 patients (77.4%) had surgical excision. The surgical margins were positive in 7 patients who presented with local recurrence after primary resection. Twelve patients developed metastatic disease. During follow-up (range 9-70 month), 26 of the 31 patients (88.9%) were alive. Significant survival differences were found according to histological type (p: 0.001), with lower survival rates for malignant fibrous histiocytoma. The tumor size, the presence of metastasis at the time of diagnosis and tumor localization were not statistically significant for overall survival.Conclusions: In our series, prostate sarcomas, paratesticular rhabdomyosarcoma and malignant fibrous histiocytoma had poor prognosis, especially in patients presenting with metastatic disease.Publication Factors influencing lymphocele development after kidney transplant: Single center experience(Başkent Üniversitesi, 2023-03-01) Sayılar, Emel Işıktaş; Ersoy, Alparslan; Ayar, Yavuz; Aydın, Mehmet Fethullah; Şahin, Ahmet Bilgehan; Coşkun, Burhan; Kaygısız, Onur; Yıldız, Abdülmecit; Kordan, Yakup; Vuruşkan, Hakan; Sayılar, Emel Işıktaş; ERSOY, ALPARSLAN; Ayar, Yavuz; Aydın, Mehmet Fethullah; ŞAHİN, AHMET BİLGEHAN; COŞKUN, BURHAN; KAYGISIZ, ONUR; YILDIZ, ABDULMECİT; Kordan, Yakup; VURUŞKAN, HAKAN; Tıp Fakültesi; İç Hastalıkları Ana Bilim Dalı; 0000-0003-4607-9220; 0000-0002-5665-7402; 0000-0002-7846-0870; 0000-0002-8242-9921; 0000-0002-9790-7295; 0000-0002-9947-848X; AAJ-8220-2020; O-9948-2015; AAH-9704-2021; L-9439-2019; JCO-5169-2023; AAM-4927-2020; HYA-4372-2023; CPX-5894-2022; HIG-9032-2022; GAF-0095-2022; EFH-9523-2022Objectives: Lymphocele is a well-known postoperative surgical complication after kidney transplant. In this study, our aim was to analyze incidence, risk factors, and outcomes of posttransplant lymphocele in a large cohort.Materials and Methods: This observational study included 395 consecutive patients (219 males and 176 females) who underwent kidney transplant procedures from 183 living and 212 deceased donors in our center between January 2007 and 2014. A lymphocele was diagnosed with ultrasonography.Results: The incidence of lymphoceles in our cohort was 31.9% (n = 126). There were no significant differences with regard to body mass indexes, age of donors, deceased donor ratios, acute rejection episodes, and history of abdominal surgery between those with and without lymphoceles. The pretransplant serum albumin levels (3.29 +/- 0.67 vs 3.48 +/- 0.69 g/dL; P = .009) in the lymphocele group and diabetes mellitus ratios (15.9% vs 4.5%; P < .001) in the nonlymphocele group were lower than levels shown in the other group. The lymphocele ratio in patients who received cyclosporine was higher than that shown in patients who did not received it (37.5% vs. 27.4%; P = .032). There was no difference in lymphocele incidence between patients who were taking and those who were not taking mammalian target of rapamycin inhibitors, mycophenolate mofetil, or mycophenolate sodium. In regression analysis, presence of diabetes mellitus, transplant from deceased donors, older age of donors, and lower albumin levels were independent risk factors for posttransplant lymphocele occurrence.Conclusions: Posttransplant lymphocele was a relatively common surgical complication in our cohort. We concluded that diabetes mellitus, use of kidneys from deceased donors, older donor age, and hypoalbuminemia were independent risk factors for lymphocele development.
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