Person: GÜVENÇ, ORHAN
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GÜVENÇ
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ORHAN
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Publication Spontaneous regression of the abdominal aortic aneurysm in a middle age female patient(Sage Publications, 2020-03-25) Engin, Mesut; Güvenç, Orhan; Göncü, Mehmet Tuğrul; GÜVENÇ, ORHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.; ACJ-3462-2022IntroductionAbdominal aortic aneurysm is an important cardiovascular disease affecting especially the elderly. Early diagnosis of this disease is particularly important for treatment success. Spontaneous regression of aneurysms has rarely been reported in the literature.MethodsA 63-year-old female patient was admitted to the internal medicine outpatient clinic with abdominal pain three years ago. A urinary ultrasonography was requested, which revealed no urinary pathology, but an abdominal aortic aneurysm of 5 cm. There were no pathological findings in routine blood tests and physical examination of the patient. Contrast-enhanced computed tomographic angiography showed an infrarenal Abdominal aortic aneurysm of approximately 4.30 x 3.24 cm. Three years later, the patient had come to the hospital for check-up with no complaints. In control computed tomographic angiography, the aneurysm was found to have regressed almost completely (2 x 2.15 cm).Results and ConclusionIn this case report, to the best of our knowledge, we aimed to share the first spontaneous regression of an abdominal aortic aneurysm in a patient without any systemic disease or use of immunosuppressive medication.Publication Visceral adiposity index and prognostic nutritional index in predicting atrial fibrillation after on-pump coronary artery bypass operations: A prospective study(Soc Brasil Cirurgia Cardiovasc, 2021-01-01) Engin, Mesut; Özşin, Kadir Kaan; Savran, Muhammed; Güvenç, Orhan; Yavuz, Şenol; Özyazıcıoğlu, Ahmet Fatih; GÜVENÇ, ORHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.; ACJ-3462-2022Introduction: Rhythm problems are the most observed complications following coronary artery bypass grafting (CABG), the most common being postoperative atrial fibrillation (PoAF), with an incidence reaching 50% of the patients. In this study, we aimed to investigate the predictive importance of prognostic nutritional index (PNI) and visceral adiposity index (VAI) in predicting PoAF, which occurs after CABG accompanied by cardiopulmonary bypass.Methods: Patients who underwent isolated CABG with cardiopulmonary bypass between June 15 and October 15, 2019, were prospectively included in the study. Patients who did not develop in-hospital PoAF were identified as Group 1, and those who did constituted Group 2.Results: PoAF developed in 55 (27.6%) patients (Group 2). The mean age of the 144 patients included in Group 1 and 55 patients in Group 2 were 56.9 +/- 8.7 and 64.3 +/- 10.2 years, respectively (P<0.001). In multivariate analysis Model 1, age (odds ratio [OR]: 1.084, confidence interval [CI]: 1.010-1.176, P=0.009), chronic obstructive pulmonary disease (OR: 0.798, CI: 0.664-0.928, P=0.048), and PM (OR: 1.052, CI: 1.015-1.379, P=0.011) were determined as independent predictors for PoAF. In Model 2, age (OR: 1.078, CI: 1.008-1.194, P=0.012), lymphocyte counts (OR: 0.412, CI: 0.374-0.778, P=0.032), and VAI (OR: 1.516, CI: 1.314-2.154, P<0.001) were determined as independent predictors for PoAF.Conclusion: In this study, we determined that low PNI, a simply calculable and cheap parameter, along with high VAI were risk factors for PoAF.Publication Levels of ischemia: Modified albumin in patients undergoing on-pump coronary artery bypass(Coll Physicians & Surgeons Pakistan, 2020-06-01) Özsin, Kadir Kaan; Balcı, Abdullah Burak; Sanri, Umut Serhat; Yavuz, Şenol; Güvenç, Orhan; GÜVENÇ, ORHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; ACJ-3462-2022Objective: To investigate the effect of ischemia-modified albumin (IMA) during cardiopulmonary bypass (CPB).Study Design: Observational study.Place and Duration of Study: Department of Cardiovascular Surgery, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January and April 2018.Methodology: Patients, who underwent on-pump coronary bypass surgery, were inducted. IMA levels were measured in the preoperative period (IMA-T-1), 30 minutes after removal of aortic X-clamp (IMA-T-2) (ischemic period) and 6th hours (IMA-T-3) after surgery. The groups were formed according to the average value of IMA-T-2 levels measured in the ischemic period. Those with a value above the mean (0.76 U/mL) were grouped as group 1 and those below the mean were grouped as group 2. Postoperative data of the patients were recorded.Results: There were significant differences between measured IMA levels in different periods of on-pump CABG (p <0.001). The development of postoperative atrial fibrillation (PoAF) was higher in Group 1 and this result was statistically significant (p=0.004). High IMA-T2 levels were detected as an independent parameter in predicting the PoAF development (p=0.04, logistic regression analysis). ROC curve analysis demonstrated IMA-T2 values of 0.73 or above could predict development PoAF with 82.6% sensitivity and 66.7% specificity (AUC: 0.777, log rank p=0.001).Conclusion: Increased IMA levels during ischemic period may be predictive in PoAF development.Publication The importance of prognostic nutritional index in predicting acute renal failure after on-pump coronary artery bypass operations in patients with insulin-dependent diabetes mellitus(Forum Multimedia Publishing, 2021-02-05) Gücü, Arif; Özlük, Özlem Arıcan; Güvenç, Orhan; Sünbül, Sadık Ahmet; Engin, Mesut; GÜVENÇ, ORHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalları.; ACJ-3462-2022Background: After coronary artery bypass graft (CABG) operations, acute kidney injury (AKI) appears at 5-30% rates, and this rate increases even more in patients with diabetes mellitus (DM). Prognostic nutritional index (PNI) is known as a valuable parameter that affects cardiovascular surgery outcomes. In this current study, we aimed to investigate the importance of PNI value in predicting AKI after on-pump CABG operations in insulin-dependent diabetic patients.Methods: A total of 254 consecutive patients with insulin-dependent diabetes who underwent on-pump CABG in our clinic between January 2016 and January 2020 retrospectively were included in this study. In the postoperative period, patients were registered as the renal failure group (Group 1), and those who did not develop renal failure were registered as Group 2.Results: A total of 255 patients with DM were included in the study. There were 82 patients in Group 1 and 173 patients in Group 2. There was no difference between the groups, in terms of age, gender, smoking, and hyperlipidemia rates. Hypertension rate significantly was higher in Group 2 (P = .001). In multivariate logistic regression analysis, hypertension (OR: 1.226, 95% CI: 1.114-2.459, P = .026), need for inotropic support (OR: 1.128, 95% CI: 1.070-1.784, P = .033), increased blood product use (OR: 1.291, 95% CI: 1.112-2.156, P =.021) preoperative high creatinine (OR: 3.563, 95% CI: 2.497-5.559, P < .001), and PNI (OR: 1.327, 95% CI: 1.118-2.785, P = .012) were independent predictors of AKI.Conclusion: In our study, we determined PNI value as an independent predictor in predicting acute renal injury occurring after on-pump CABG operations in patients with insulin-dependent DM.Publication Predictive value of hatch scoring and waist-to-height ratio in atrial fibrillation following coronary artery bypass operations performed with cardiopulmonary bypass(Digital Commons Bepress, 2021-01-01) Savran, Muhammed; Engin, Mesut; Güvenç, Orhan; Yüksek, Hasan F.; Sunbül, Sadık Ahmet; Türk, Tamer; Ata, Yusuf; Aydın, Ufuk; Özyazıcıoğlu, Ahmet F.; GÜVENÇ, ORHAN; Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı; ACJ-3462-2022Objectives: Postoperative atrial fibrillation (PoAF), an important clinical condition that can occur after coronary artery bypass graft (CABG) operations, may bring about cerebrovascular risks, prolong hospital stay and increase treatment costs. In this prospective study, we aimed to investigate the predictive value of HATCH score and waist/height ratio (WHR) values in revealing the development of PoAF after CABG operations.Methods: Patients who underwent isolated CABG surgery with cardiopulmonary bypass between May 2019 and November 2019 were prospectively included in the study. Preoperative demographic characteristics, laboratory parameters, and operative parameters of the patients were recorded prospectively.Results: A total of 255 patients were included in the study. Those who did not develop PoAF were included in Group 1 (N = 196, mean age = 58.9 +/- 9.4 years), and those who did were included in Group 2 (n = 59, mean age = 61.1 +/- 12 years). There were no statistically significant differences between the two groups in terms of age, gender, presence of hypertension and hyperlipidemia. Rates of chronic obstructive pulmonary disease and previous percutaneous coronary interventions, waist circumference, waist to height ratio and HATCH score values were significantly higher in Group 2 compared to Group 1 (p values: 0.019, 0.034, 0.001, <0.001, <0.001, respectively). In multivariate analysis, WHR (Odds ratio: 1.068, Confidence interval: 1.032-1.105, p < 0.001) and HATCH score (Odds ratio: 2.590, Confidence interval: 1.850-3.625, p < 0.001) were independent predictors of PoAF.Conclusions: With this current prospective study, we showed that calculating WHR and HATCH score in the preoperative period can help us predict PoAF.