Person: BİLGİN, YÜCEL
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BİLGİN
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YÜCEL
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Publication Effects of repeated intravenous doses of tranexamic acid on closed tibial fracture healing: Experimental study based on the rat model(Turkish Assoc Orthopaedics Traumatology, 2023-09-01) Doğan, İbrahim; Birişik, Fevzi; Kalyenci, Ahmet Sinan; Bozkurt, Erol Rüstü; Öztürkmen, Yusuf; Bilgin, Yücel; BİLGİN, YÜCEL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.Objective: The aim of this study was to assess the effects of tranexamic acid on fracture healing in the rat tibia closed fracture model.Methods: Sixty-four male Sprague-Dawley rats were included in this study, where closed fracture and intramedullary nailing were performed on their right tibial diaphyses. They were divided into 2 main groups, the experimental group, which was given weekly tranexamic acid injections, and the control group, which received no additional treatment. Eight rats from each group were sacrificed and evaluated for fracture healing at the first experimental group and control group, second experimental group and control group, third experimental group and control group, and fourth experimental group and control group weeks. Fracture healing was radiologically assessed according to the "Spencer Index" and "Lane and Sandhu Scoring System," and histologically evaluated according to the scoring system devised by Huo et al.Results: According to the Spencer Index, the mean union score was statistically significantly higher in the E3 group than in the third con-trol group (P = .014). Furthermore, the mean union score was statistically significantly higher in the fourth experimental group compared to the fourth control group (P = .047). According to the Lane and Sandhu Scoring System, only the mean union scores of the E3-4 groups were statistically significantly higher than the mean union scores of the C3-4 groups (P = .048). There was no histological difference between groups in terms of union, according to the criteria defined by Huo et al (P > .05).Conclusion: This study showed us that repeated intravenous administrations of tranexamic acid had no negative effect on fracture heal-ing in the rat tibia fracture model. Although tranexamic acid demonstrated better radiological healing in the late period, it had no effect on histological union.Publication Comparing the trajectory accuracy of pedicle screws placed with a free-hand technique and a three-dimensional computed tomography-assisted navigation system in spine surgery: A retrospective study(İstanbul Üniversitesi, 2023-02-28) Çetiner, Eyyup; Akesen, Selcan; Bilgin, Yücel; Önder, Cem; Güler, Saltuk Buğra; Akesen, Burak; AKESEN, SELCAN; BİLGİN, YÜCEL; Güler, Saltuk Buğra; AKESEN, BURAK; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.; ELR-9087-2022; IAI-7796-2023; ADT-9515-2022; AAH-9833-2021Objective: We evaluated a free-hand technique and a three-di-mensional computerized tomography (3D-CT)-assisted naviga-tion technique, which are pedicle screw placement techniques used in spinal surgery, regarding screw placement and reliability.Material and Method: A total of 1664 screws in 73 patients with spinal deformities who underwent spinal instrumentation using pedicle screws were evaluated in this study. Forty patients were in the free-hand technique group, and 33 patients were in the 3D-CT-assisted navigation technique group. The placement and reliability of pedicle screws in all patients were evaluated using the Gertzbein-Robbins classification using CT images taken in the postoperative period.Result: There were no significant differences found regarding age, body mass index (BMI), sex (female or male), or deformity (scoliosis or kyphosis) (p>0.05). When the pedicle screws were evaluated in terms of transverse penetration, the 3D-CT-assisted navigation technique was determined Grade A (89.6%), as was the free-hand technique (76.5%), but the 3D-CT-assisted navi-gation technique was statistically more reliable (p<0.001). When the pedicle screws were evaluated in terms of anterior penetra-tion, both the 3D-CT-assisted navigation technique (92.5%) and the free-hand technique (82.9%) were determined Grade A, but the 3D-CT-assisted navigation technique was statistically more reliable (p<0.001).Conclusion: According to our studys results, the 3D-CT-assist-ed navigation technique is more reliable than the free-hand technique in surgeries involving spine deformities for pedicle screw insertion.Publication Comparison of clinical and radiological results of lateral retinacular release or lateral retinacular lengthening methods combined with medial retinaculum plication in patellofemoral instability(Springernature, 2022-09-28) Saylık, Murat; Bilgin, Yücel; Atıcı, Teoman; BİLGİN, YÜCEL; ATICI, TEOMAN; 0000-0003-0433-1918; GSN-6364-2022; A-5095-2018IntroductionIn this study, we aimed to compare the clinical and radiological results of patients who underwent medial retinaculum plication (MRP) combined with lateral retinacular release (LRR) or lateral retinacular lengthening (LRL) with the diagnosis of patellofemoral (PF) instability.MethodsIn our study, we retrospectively analyzed 75 knees of 75 adult patients (43 females and 32 males) who underwent MRP+LRR or MRP+LRL due to PF instability without osseous pathologies. Patients were divided into two groups (MRP+LRR and MRP+LRL) according to the surgical method. The clinical and radiological results of the two groups were compared.ResultsMRP+LRL surgery was performed on 45 knees and MRP+LRR surgery on 30 knees. The mean age was 26.5 (18-43) years. There was no significant difference between the two groups in the change in patellar lateral shift (PLS) (p=0.429) and congruence angle (CA) (p=0.218) values. However, there was a significant difference between the two groups in the change in patellar tilt angle (PTA) (p=0.009) and lateral patellofemoral angle (LPFA) (p<0.001) values. The change in PTA and LPFA values was higher in the MRP+LRL group. There was no significant difference between the two groups in terms of pre-operative and post-operative Lysholm knee scoring scale (p=0.205, p=0.228), Kujala pain scale (p=0.393, p=0.596), and Tegner activity level scale values (p=0.121, p=0.899).ConclusionsMRP+LRR or MRP+LRL provided successful results for correcting the instability in PF instability without osseous pathologies such as patella alta, tibial tubercle-trochlear groove (TT-TG) dysplasia, trochlea dysplasia, genu valgus, and tibial-femoral torsion. While PTA and LPFA values improved more with the MRP-LRL method, clinical results were similar in both methods.