Person: AKGÜR, SUAT
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Publication Investigation of the tissue allele distribution of the deceased kidney donors between 2007 and 2017.(Lippincott Williams & Wilkins, 2019-11-01) Oflaz, Rafet; Elgin, Ersin; Yıldız, Abdülmecid; Oruç, Ayşegül; Akgür, Suat; Ünsal, Oktay; Karaca, Mert; Ersoy, Sahriye; Selimoğlu, Kerem; Arslan, İlknur; Karan, Elif; Çiçek, Mehmet Çağatay; Günseren, Kadir Ömür; Güllülü, Sümmeyye; Vuruşkan, Hakan; Oflaz, Rafet; Elgin, Ersin; Yıldız, Abdülmecid; ORUÇ, AYŞEGÜL; AKGÜR, SUAT; Ünsal, Oktay; KARACA, MERT; Ersoy, Sahriye; Selimoğlu, Kerem; Arslan, İlknur; Karan, Elif; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; GÜLLÜLÜ, NAZMİYE SÜMEYYE; VURUŞKAN, HAKAN; Tıp Fakültesi; Organ Nakli Merkezi; 0000-0002-9509-5799; 0000-0002-0342-9692; 0000-0003-3635-7282; 0000-0002-3454-8483; 0000-0002-0471-5404; 0000-0001-6711-676X; AAG-7406-2021; AAH-4002-2021; DJU-5362-2022; DXA-2790-2022; EIF-8983-2022; JIX-1144-2023; JJY-8484-2023; AAG-7406-2021; EVS-9805-2022; CDS-3299-2022; CCH-8947-2022; FDB-4488-2022; HGM-5995-2022; EFH-9523-2022; CST-9838-2022; ITO-9188-2023Publication Screening for fabry disease in patients who underwent renal biopsy and identification of a novel mutation(Aves, 2021-04-01) Oruç, Ayşegül; Yıldız, Abdulmecit; Akgür, Suat; Aydın, Mehmet Fethullah; Ersoy, Alparslan; Yavuz, Mahmut; Dilek, Kamil; Güllülü, Mustafa; ORUÇ, AYŞEGÜL; YILDIZ, ABDULMECİT; AKGÜR, SUAT; Aydın, Mehmet Fethullah; ERSOY, ALPARSLAN; YAVUZ, MAHMUT; DİLEK, KAMİL; GÜLLÜLÜ, MUSTAFA; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; 0000-0002-0342-9692; 0000-0002-5665-7402; AAJ-8220-2020; AAH-4002-2021; HIG-9032-2022; EJA-1761-2022; CPX-5894-2022; EHM-7377-2022; EUF-5229-2022; JGS-9425-2023Background: The X-linked Fabry disease (FD) with lysosomal storage of globotriaosylceramide (Gb3) due to alpha-galactosidase deficiency contributes to nephropathy consisting of proteinuria and renal failure eventually. Early initiation of the enzyme replacement therapy promises favorable renal outcomes. With the importance of early diagnosis, we screened FD among proteinuric patients in whom biopsy findings revealed Fabry nephropathy.Methods: Patients with light microscopic biopsy findings of vacuolated cells, focal and/or segmental glomerular sclerosis, tubular atrophy, and interstitial fibrosis were not associated with particular etiology, the presence of acro-paresthesia, angiokeratomas, and cornea verticillata, stroke history younger than 50 years, family history of renal failure with no cardiovascular risk factors were screened. Fifty-three of 308 consecutive adult patients (45.34 +/- 15.23 years old, 60.1% male) who underwent renal biopsy because of proteinuria were enrolled in the study. Screening for FD was performed by assessing alpha-Gal A activity in dried blood spots (DBS) for males and by genetic testing for females.Results: Fifty-three patients (39.94 +/- 11.97 years, 69.8% male) who underwent renal biopsy were screened. Laboratory findings revealed mean serum creatinine of 1.44 +/- 1.06 mg/dL, mean estimated glomerular filtration rate of 78.31 +/- 39.89 mL/min/1.73 m(2), and mean proteinuria of 4.32 +/- 3 g/day, whereas the females genetic screening was negative. Two of 37 males had low enzyme activity (<0.1 micmol/L/h) and confirmed FD by genetic analysis in whom one had a novel mutation of GLA gene (c.(1047G>A) p.(Trp349*)).Conclusion: It is worth noting that FD screening in patients with proteinuria, in whom vacuolated cells, mesangial expansion, glomerulosclerosis, interstitial fibrosis, and tubular atrophy of unknown etiology, are present in the renal biopsy either with or without a family history of kidney disease.Publication The outcomes of kidney transplantation from elder deceased donors a single center experience(Lippincott Williams & Wilkins, 2019-11-01) Selimoğlu, Kerem; Elgin, Ersin; Yıldız, Abdülmecit; Oruç, Ayşegül; Akgür, Suat; Ünsal, Oktay; Keskin, Sahriye; Oflaz, Rafet; Arslan, İlknur; Karan, Elif; Çiçek, Mehmet Çağatay; Günseven, Kadir Ömür; Karaca, Mert; Güllülü, N. Sümeyye; Vuruşkan, Hakan; Ersoy, Alparslan; Selimoğlu, Kerem; Elgin, Ersin; Yıldız, Abdülmecit; ORUÇ, AYŞEGÜL; AKGÜR, SUAT; Ünsal, Oktay; Keskin, Sahriye; Oflaz, Rafet; Arslan, İlknur; Karan, Elif; ÇİÇEK, MEHMET ÇAĞATAY; Günseven, Kadir Ömür; KARACA, MERT; GÜLLÜLÜ, NAZMİYE SÜMEYYE; VURUŞKAN, HAKAN; ERSOY, ALPARSLAN; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; 0000-0003-3635-7282; 0000-0002-9509-5799; 0000-0002-0342-9692; 0000-0002-3454-8483; 0000-0002-0471-5404; CDS-3299-2022; DXA-2790-2022; HIG-9032-2022; AAH-4002-2021; EJA-1761-2022; JJY-8484-2023; CZH-6714-2022; DJU-5362-2022; CCH-8947-2022; FDB-4488-2022; HGM-5995-2022; CUF-3990-2022; AAG-7406-2021; CTR-6558-2022; EFH-9523-2022; AAH-5054-2021Publication The prevalence, clinical and pathological characteristics of primary focal segmental glomerulosclerosis in Turkish adults: The data from tsn-gold (Turkish society of nephrology glomerular diseases) working group(Oxford Univ Press, 2020-06-01) Kurultak, İlhan; Güngör, Özkan; Öztürk, Savaş; Dirim, Ahmet Burak; Eren, Necmi; Yenigün, Ezgi; Dal, Elbis Ahbap; Dinçer, Mevlüt Tamer; Bora, Feyza; Akgür, Suat; Sumnu, Abdullah; Dursun, Belda; Sipahi, Savaş; Getinkaya, Hakkı; Sahin, Idris; Şahin, Garip; Yılmaz, Mürvet; Vatansever, Bülent; Aydın, Emre; Ulu, Memnune Sena; Gündoğan, Ali; ÜstOndağ, Sedat; Sayarlıoğlu, Hayriye; Şahin, Gizem Kumru; Elcioğlu, Ömer Celal; Aydın, Zeki; Selcuk, Nedim Yılmaz; Önal, Ceren; Oruç, Meriç; Küçük, Mehmet; Aktaş, Nimet; Derici, Ulver; Süleymanlar, Gültekin; AKGÜR, SUAT; Tıp Fakültesi; JIX-1144-2023Publication The effect of medical complications on early graft function after kidney transplantation(Frontiers Media Sa, 2019-10-01) Düger, Hakan; Ersoy, Alparslan; Oruç, Ayşegül; Yıldız, Abdülmecit; Ünsal, Oktay; Akgür, Suat; Ersoy, Canan; Aydın, Mehmet Fethullah; Düger, Hakan; ERSOY, ALPARSLAN; ORUÇ, AYŞEGÜL; YILDIZ, ABDULMECİT; Ünsal, Oktay; AKGÜR, SUAT; ERSOY, CANAN; Aydın, Mehmet Fethullah; Tıp Fakültesi; İç Hastalıkları Ana Bilim Dalı; 0000-0001-5478-3192; 0000-0002-0342-9692; 0000-0002-5665-7402; AAJ-8220-2020; AAH-8861-2021; AAH-4002-2021; GPK-6118-2022; IZP-9361-2023; AAH-5054-2021; HIG-9032-2022; JJY-8484-2023; EJA-1761-2022Publication A rare cause of posterior reversible leukoencephalopathy after kidney transplantation(Frontiers Media Sa, 2019-10-01) Ersoy, Alparslan; Ersoy, Yavuz; Kır, Elif; Kaya, Ahmet; Oruç, Ayşegül; Akgür, Suat; Ünsal, Oktay; Hakyemez, Bahattin; ERSOY, ALPARSLAN; Kır, Elif; KAYA, AHMET TUFAN; ORUÇ, AYŞEGÜL; AKGÜR, SUAT; Ünsal, Oktay; HAKYEMEZ, BAHATTİN; Tıp Fakültesi; Radiyoloji Ana Bilim Dalı; 0000-0001-9094-9735; 0000-0002-0342-9692; AAH-5054-2021; AAI-2318-2021; AAH-4002-2021; CZH-4661-2022; JYF-5512-2024; EJA-1761-2022; JJY-8484-2023Publication The relationship between surgical complications and graft outcomes after kidney transplantation(Wiley, 2019-10-01) Düger, Hakan; Ersoy, Alparslan; Dizdar, Oğuzhan Sıtkı; Yıldız, Abdulmecit; Oruç Ayşegül; Ünsal, Oktay; Akgür, Suat; Kordan, Yakup; Kaygısız, Onur; Coşkun, Burhan; Vuruskan, Hakan; Düger, Hakan; ERSOY, ALPARSLAN; Dizdar, Oğuzhan Sıtkı; YILDIZ, ABDULMECİT; ORUÇ, AYŞEGÜL; Ünsal, Oktay; AKGÜR, SUAT; Kordan, Yakup; KAYGISIZ, ONUR; COŞKUN, BURHAN; VURUŞKAN, HAKAN; Tıp Fakültesi; Nefroloji Bölümü; 0000-0001-5478-3192; 0000-0002-0342-9692; 0000-0002-9947-848X; 0000-0002-9790-7295; 0000-0002-8242-9921; AAM-9726-2020; AAH-5054-2021; AAH-4002-2021; AAH-9704-2021; IZP-9361-2023; JCO-5169-2023; L-9439-2019; D-6213-2013; GPK-6118-2022Publication Nocardia cyriacigeorgica pneumonia mimicking lung cancer in a kidney transplant patient(Wiley, 2019-10-01) Ersoy, Alparslan; Gül, Cuma Bülent; Yıldız, Abdulmecit; Oruç, Ayşegül; Ünsal, Oktay; Akgür, Suat; Akalın, Halis; ERSOY, ALPARSLAN; YILDIZ, ABDULMECİT; ORUÇ, AYŞEGÜL; Ünsal, Oktay; AKGÜR, SUAT; AKALIN, EMİN HALİS; Tıp Fakültesi; Microbioloji Bölümü; 0000-0003-2467-9356; 0000-0002-0342-9692; 0000-0001-7530-1279; AAU-8952-2020; AAH-5054-2021; AAH-4002-2021; HIG-9032-2022; JJY-8484-2023; EJA-1761-2022Publication Morning blood pressure surge in early autosomal dominant polycystic kidney disease and its relation with left ventricular hypertrophy(Oxford Univ Press, 2018-05-01) Yıldız, Abdulmecit; Sağ, Saim; Gül, Cuma; Can, Fatma; Oruç, Aysegül; Aydın, Mehmet; Bedir, Ömer; Akgür, Suat; Ayar, Yavuz; Güllülü, Sürneyye; Güllülü, Mustafa; Ersoy, Alparslan; YILDIZ, ABDULMECİT; Can, Fatma; ORUÇ, AYŞEGÜL; AYDIN, MEHMET AKİF; Bedir, Ömer; AKGÜR, SUAT; Ayar, Yavuz; GÜLLÜLÜ, NAZMİYE SÜMEYYE; GÜLLÜLÜ, MUSTAFA; ERSOY, ALPARSLAN; Tıp Fakültesi; Dahiliye Bölümü; 0000-0003-2467-9356; 0000-0002-0342-9692; 0000-0002-5665-7402; 0000-0003-4607-9220; 0000-0002-5665-7402; AGF-0767-2022; GSE-0029-2022; AAH-5054-2021; AAH-4002-2021; O-9948-2015; HIG-9032-2022; IBQ-9926-2023; AAJ-8220-2020; IVE-3975-2023; EJA-1761-2022; EWD-8403-2022; JGS-9425-2023Publication Exclusion reasons of cadaveric kidney transplantation candidates(Türk Nefroloji Diyaliz Transplantasyon Dergisi, 2018-01-01) Oruç, Ayşegül; Ersoy, Alparslan; Ayar, Yavuz; Akgür, Suat; Yıldız, Abdülmecit; ORUÇ, AYŞEGÜL; ERSOY, ALPARSLAN; Ayar, Yavuz; AKGÜR, SUAT; YILDIZ, ABDULMECİT; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; 0000-0002-0342-9692; 0000-0003-4607-9220; AAH-4002-2021; AGF-0767-2022; O-9948-2015; AAH-5054-2021; GSE-0029-2022OBJECTIVE: Cadaveric organ donation is not at desired levels in our country. However, the number of patients on cadaveric kidney waiting lists is increasing. This situation also makes it difficult to follow cadaveric kidney recipient candidates at transplantation centers. It is very important for the medical status and information of the waitlisted candidates to be current at the time of the cadaveric kidney transplant call. In this study, we investigated the exclusion reasons of cadaveric transplantation candidates at our center.MATERIAL and METHODS: A total 252 adults called for cadaveric kidney transplantation between January 2013 and August 2015 were included the study. Electronic data, immunology laboratory results and transplantation council records were examined. Exclusion reasons of the candidates were evaluated according to the list order. Candidates with a lower rank than the transplanted candidate were excluded.RESULTS: In this period, 252 (56.7% male, 43.3% female, 46.2 +/- 12.2 years) adults were called for 81 cadaveric donors (120 kidneys). A total of 144 (57.1%) candidates were excluded. Exclusion reasons were being unable/unwilling to come to the center (59, 34.1%), positive lymphocyte cross-match test (40, 22.9%), inability to reach the patient (24, 13.9%), chronic HCV infection (20, 11.6%), active infection (11, 6.6%), cardiovascular reasons (8, 4.6%), and respiratory system disorders (5, 2.5%).CONCLUSION: Unexpected problems of cadaveric donor candidates can lead to exclusion from transplantation. It will therefore be useful to maintain contact between the patient and his/her relatives and the dialysis and organ transplantation centers, and to update the candidates' information.