Person: BATMAZ, HASAN
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BATMAZ
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HASAN
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Publication Effects of vitamin d administration at the beginning of lactation in dairy cows on inflammatory response and liver metabolism(Tubitak Scientific & Technological Research Council Turkey, 2021-11-26) Kaya, Feyyaz; Batmaz, Hasan; Kaya, Feyyaz; Batmaz, Hasan; BATMAZ, HASAN; Bursa Uludağ Üniversitesi/Veteriner Fakültesi.; 0000-0001-8820-1509; IXN-7700-2023This study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response. Twenty multiparous Holstein cows were randomly assigned to the experimental (EG) and control group (CG). The EG received 5,000,000 IU vitamin D 3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl. Blood samples were taken 24 h after parturition before treatments and at the 3rd, 7th, 14th, and 28th days of lactation. Serum NEFA, BHBA, haptoglobin, serum amyloid A (SAA), ceruloplasmin, calcium, phosphorus, parathormone, total protein, triglyceride, AST, and GGT were measured. In addition, total bilirubin, albumin, total cholesterol, and vitamin A concentrations were also measured to calculate liver activity index and the liver functionality index. Subclinical hypocalcemia (SCH) was observed in only one cow in the EG and five in the CG after the 3rd day postpartum. NEFA levels in the EG significantly differed on days 7, 14, and 28 when compared to vitamin D pretreatment values. However, NEFA levels in the CG differed only between day 28 postpartum and the 1st day (p < 0.05). Negative correlation was determined between vitamin D and NEFA (p < 0.01). Conversely, negative correlations were observed between calcium and NEFA, haptoglobin, SAA (p < 0.05). In conclusion, it can be suggested that vitamin D administration can prevent SCH after the 3rd day and has limited positive effects on postpartum NEFA levels.Publication Early clinical predictors of diarrhea in the first fifteen days in dairy calves and their relationship with passive transfer status(Polish Soc Veterinary Sciences Editorial Office, 2020-05-01) Topal, Onur; Batmaz, Hasan; BATMAZ, HASAN; Bursa Uludağ Üniversitesi/Veteriner Fakültesi.; 0000-0002-1933-7354; AAH-1712-2021; S-8278-2017The neonatal period is very important in calves. It is extremely important to closely monitor newborn calves with good colostrum management during this period. In this study, the aim was to investigate whether the clinical parameters in the first 15 days after calves are born are correlated with diarrhea and whether those values are the early clinical predictors of the diarrhea that will occur in this period and also to investigate the correlation between diarrhea and the failure of transfer of passive immunity (FTPI). Eighty-two Holstein calves were used in the study. The calves were examined systemically every day and were scored according to a standard form. In the first 15 day period, 64.63% of the calves had diarrhea. In diarrheic calves, the most common findings on the previous day without diarrhea were fetid feces (43.40%), changes in the consistency and color of feces, and a decrease in the temperature of the ears (35.85%). According to non diarrheic calves, fetid feces (P < 0.01), changes in the consistency and color of feces, and nasal discharge were more common among diarrheic calves on the day before diarrhea (p < 0.001). The duration of diarrhea in calves with FTPI was longer than without FTPI. As a result, it is important for calves to be monitored daily in the first 15 days, looking for early signs of diarrhea in this period, namely fetid feces and changes in the consistency and the color of the feces. In addition, coexistence of any fecal changes with the decrease in the temperature of the ears may be clinical predictors of diarrhea. As a result of the daily monitoring of the calves, although the morbidity rate was high, none of the animals died.Publication Acute interstitial pneumonia in nongrazing cows(Kafkas Üniversitesi Veteriner Fakultesi Dergisi, 2021-09-01) Batmaz, Hasan; CangÜl, İbrahim Taci; BATMAZ, HASAN; CANGÜL, İBRAHİM TACİ; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Dahiliye Tıp Bölümü; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Bölümü; 0000-0003-0537-2113; HXD-1722-2023; AAB-4360-2021Publication Evaluation of serum choline along with, some biochemical and clinical parameters in cattle suffering from with botulism(Pakistan Agricultural Scientists Forum, 2021-02-01) Batmaz, Hasan; Mecitoğlu, Zafer; Koç, Cansu; Kaya, Fatih; Topal, Onur; Cansev, Mehmet; BATMAZ, HASAN; MECİTOĞLU, ZAFER; KOÇ, CANSU; KAYA, FATİH; TOPAL, ONUR; CANSEV, MEHMET; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Farmakoloji Anabilim Dalı; 0000-0002-6097-5585; 0000-0001-8820-1509; 0000-0002-1933-7354; 0000-0003-2918-5064; M-9071-2019; AAA-4754-2022; IXN-7700-2023; S-8278-2017; HXD-1722-2023; FQB-3477-2022Botulism is a disease of cattle that causes significant impact due to its high mortality rate. The aim of the present study is to evaluate serum choline levels as well as clinical and biochemical parameters of cattle suspected to be suffering from botulism and to compare the results with healthy cattle and also to compare the results of survivors and fatalities. Thirteen botulism suspected and eleven healthy cattle were used. Total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transferase (GGT), calcium, phosphorus, magnesium and potassium levels were measured from the sera of botulism and control cattle by colorimetric method using an autoanalyser. Choline levels were analyzed using HPLC. Dysphagia, decreased tongue strength weak anal reflexes, tongue and tail paralysis and locomotion disorders were the main clinical findings observed in suspected botulism cases. Botulinum toxin analysis of ruminal fluid samples were positive in two cattle from one herd. AST, ALT, potassium and choline levels were higher in cattle suffering from suspected botulism cases and choline levels were positively correlated with albumin and total protein levels. Three animals from botulism group survived. Clinical findings were milder, animals were not recumbent and choline levels were lower in survivors. Clinical findings of the three animals that recovered were milder, animals were not recumbent and choline levels were lower in survivors. It was observed that clinical findings such as decreased tongue strength and anal reflexes, dysphagia, tail paralysis, and locomotion disorders are important for diagnosis of botulism In conclusion, cattle with milder clinical signs and lower choline have a higher chance of survival.