Person: ERSOY, ALPARSLAN
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
ERSOY
First Name
ALPARSLAN
Name
79 results
Search Results
Now showing 1 - 10 of 79
Publication The relationship between marginal and non-marginal kidney transplants(Lippincott Williams & Wilkins, 2018-07-01) Elgin, Ersin; Selimoğlu, Abdülmecid Yıldız Kerem; Keskin, Sahriye; Ersoy, Alparslan; ERSOY, ALPARSLAN; Çınar, Yavuz Selim; Dündar, Halit Ziya; DÜNDAR, HALİT ZİYA; Tıp Fakültesi; Organ Nakli Merkezi; 0000-0002-9509-5799; AAH-5054-2021Publication Association of morning blood pressure surge (mbps) with left ventricular hypertrophy in autosomal dominant polycystic kidney disease (ADPKD): Across sectional study(Oxford Univ Press, 2016-05-01) Sağ, Saim; Yıldız, Abdulmecit; Ersoy, Alparslan; Ocakoğlu, Gökhan; Oruç, Ayşegül; Güngören, Fatih; Ayar, Yavuz; Gül, Cuma Bülent; Güllülü, Sümeyye; Güllülü, Mustafa; Sağ, Saim; YILDIZ, ABDULMECİT; ERSOY, ALPARSLAN; OCAKOĞLU, GÖKHAN; ORUÇ, AYŞEGÜL; Güngören, Fatih; Ayar, Yavuz; GÜL, CUMA BÜLENT; GÜLLÜLÜ, NAZMİYE SÜMEYYE; GÜLLÜLÜ, MUSTAFA; Tıp Fakültesi; Kardioloji Bölümü; 0000-0002-1114-6051; 0000-0002-0342-9692; 0000-0003-4607-9220; 0000-0003-2467-9356; AAH-5180-2021; AGF-0767-2022; AAW-9185-2020; AAH-5054-2021; O-9948-2015; AAA-3163-2021; HLG-6346-2023; AAH-4002-2021; A-7063-2018; GSE-0029-2022; HIG-9032-2022; JGR-6552-2023; CTG-8811-2022Publication The effect of education level on early diagnosis in ADPKD(Oxford Univ Press, 2019-06-01) Yıldız, Abdulmecit; Ersoy, Alparslan; YILDIZ, ABDULMECİT; ERSOY, ALPARSLAN; Tıp Fakültesi; AAH-5054-2021; HIG-9032-2022Publication Irritable bowel syndrome in patients on renal replacement treatment(Oxford Univ Press, 2015-05-01) Aktaş, Nimet; Oruç, Ayşegül; Ersoy, Alparslan; Coşkun, Belkıs Nihan; Gül, Bülent; Yıldız, Abdulmecit; Ayar, Yavuz; Sayılar, Emel Işıktaş; Aktaş, Nimet; ORUÇ, AYŞEGÜL; ERSOY, ALPARSLAN; COŞKUN, BELKIS NİHAN; GÜL, CUMA BÜLENT; YILDIZ, ABDULMECİT; Ayar, Yavuz; Sayılar, Emel Işıktaş; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; 0000-0002-0342-9692; 0000-0003-4607-9220; 0000-0002-0710-0923; 0000-0003-0298-4157; AGF-0767-2022; AAH-4002-2021; AAH-5054-2021; O-9948-2015; AAG-7155-2021; GSE-0029-2022; W-2575-2017Publication Evaluation of serum spondin 2 levels in the different etiologies of glomerular diseases(Oxford University, 2015-05-01) Kahvecioğlu, Serdar; Ersoy, Alparslan; Ayar, Yavuz; Güçlü, Metin; Gül, Cuma Bülent; Üstündağ, Yasemin; Doğan, Ibrahim; Yıldız, Abdülmecit; ERSOY, ALPARSLAN; AYAR, YAVUZ; YILDIZ, ABDULMECİT; 0000-0003-4607-9220; 0000-0002-0710-0923; AGF-0767-2022; AAH-5054-2021; HIG-9032-2022Publication Screening for fabry disease in patients who underwent renal biopsy and identification of a novel mutation(Aves, 2021-04-01) Oruç, Ayşegül; Yıldız, Abdulmecit; Akgür, Suat; Aydın, Mehmet Fethullah; Ersoy, Alparslan; Yavuz, Mahmut; Dilek, Kamil; Güllülü, Mustafa; ORUÇ, AYŞEGÜL; YILDIZ, ABDULMECİT; AKGÜR, SUAT; Aydın, Mehmet Fethullah; ERSOY, ALPARSLAN; YAVUZ, MAHMUT; DİLEK, KAMİL; GÜLLÜLÜ, MUSTAFA; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; 0000-0002-0342-9692; 0000-0002-5665-7402; AAJ-8220-2020; AAH-4002-2021; HIG-9032-2022; EJA-1761-2022; CPX-5894-2022; EHM-7377-2022; EUF-5229-2022; JGS-9425-2023Background: The X-linked Fabry disease (FD) with lysosomal storage of globotriaosylceramide (Gb3) due to alpha-galactosidase deficiency contributes to nephropathy consisting of proteinuria and renal failure eventually. Early initiation of the enzyme replacement therapy promises favorable renal outcomes. With the importance of early diagnosis, we screened FD among proteinuric patients in whom biopsy findings revealed Fabry nephropathy.Methods: Patients with light microscopic biopsy findings of vacuolated cells, focal and/or segmental glomerular sclerosis, tubular atrophy, and interstitial fibrosis were not associated with particular etiology, the presence of acro-paresthesia, angiokeratomas, and cornea verticillata, stroke history younger than 50 years, family history of renal failure with no cardiovascular risk factors were screened. Fifty-three of 308 consecutive adult patients (45.34 +/- 15.23 years old, 60.1% male) who underwent renal biopsy because of proteinuria were enrolled in the study. Screening for FD was performed by assessing alpha-Gal A activity in dried blood spots (DBS) for males and by genetic testing for females.Results: Fifty-three patients (39.94 +/- 11.97 years, 69.8% male) who underwent renal biopsy were screened. Laboratory findings revealed mean serum creatinine of 1.44 +/- 1.06 mg/dL, mean estimated glomerular filtration rate of 78.31 +/- 39.89 mL/min/1.73 m(2), and mean proteinuria of 4.32 +/- 3 g/day, whereas the females genetic screening was negative. Two of 37 males had low enzyme activity (<0.1 micmol/L/h) and confirmed FD by genetic analysis in whom one had a novel mutation of GLA gene (c.(1047G>A) p.(Trp349*)).Conclusion: It is worth noting that FD screening in patients with proteinuria, in whom vacuolated cells, mesangial expansion, glomerulosclerosis, interstitial fibrosis, and tubular atrophy of unknown etiology, are present in the renal biopsy either with or without a family history of kidney disease.Publication Factors influencing lymphocel development after kidney transplantation: Single center experience(Oxford University Press, 2015-05-01) Sayılar, Emel Işıktaş; Ersoy, Alparslan; Ayar, Yavuz; Aydın, Mehmet Fethullah; Şahin, Ahmet Bilgehan; Coşkun, Burhan; Kaygısız, Onur; Yıldız, Abdulmecit; Kordan, Yakup; Vuruşkan, Hakan; SAYILAR, EMEL IŞIKTAŞ; ERSOY, ALPARSLAN; AYAR, YAVUZ; AYDIN, MEHMET FETHULLAH; ŞAHİN, AHMET BİLGEHAN; COŞKUN, BURHAN; KAYGISIZ, ONUR; YILDIZ, ABDULMECİT; KORDAN, YAKUP; VURUŞKAN, HAKAN; 0000-0003-4607-9220; 0000-0002-5665-7402; 0000-0002-7846-0870; 0000-0002-8242-9921; 0000-0002-9790-7295; 0000-0002-9947-848X; 0000-0002-0710-0923; AAH-5054-2021; O-9948-2015; L-9439-2019; JCO-5169-2023; AAH-9704-2021; AGF-0767-2022; AAJ-8220-2020; AAM-4927-2020; GSE-0029-2022; W-2575-2017; AAM-9726-2020; HIG-9032-2022; GAF-0095-2022; EFH-9523-2022Publication Monocyte-to-high-density lipoprotein cholesterol ratio is independently associated with all-cause mortality in deceased donor kidney transplant recipients(Başkent Üniversitesi, 2021-10-01) Çiçek, Mehmet Çagatay; Günseren, Kadir Omur; Aydın, Yavuz Mert; Yıldız, Abdulmecit; Elgin, Ersin; Ersoy, Alparslan; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; AYDIN, YAVUZ MERT; YILDIZ, ABDULMECİT; Elgin, Ersin; ERSOY, ALPARSLAN; Tıp Fakültesi; Transplantasyon Bölümü; 0000-0002-0471-5404; 0000-0001-8673-3093; 0000-0002-6287-6767; 0000-0002-9509-5799; ABC-9924-2020; AFP-3055-2022; HGM-5995-2022; HIG-9032-2022; DXA-2790-2022; CPX-5894-2022Objectives: The primary objective of this study was to evaluate the impact of monocyte-to-high-density lipoprotein cholesterol ratio on all-cause mortality in deceased donor kidney transplant recipients. Materials and Methods: This was a retrospective observational study in which all deceased donor kidney transplant recipients were included. Relevant data for analyses included clinical and demographic features, laboratory values, number of HLA matches, occurrence of delayed graft function, cold ischemia time, and survival status. Kaplan-Meier survival analysis and Cox proportional hazards analysis were performed to determine the effects of monocyte-tohigh-density lipoprotein cholesterol ratio on all-cause mortality. Results: Our study included 325 deceased donor kidney transplant recipients (43.1% females, mean age of 44.5 +/- 11.2 years). Median value of monocyte-tohigh-density lipoprotein cholesterol ratio was 14.0 (interquartile range, 9.94-21.03). The total median observation time was 227 weeks (range, 115-345 weeks). Twenty deaths (12.3%) occurred during the follow-up period in recipients with monocyte-to-highdensity lipoprotein cholesterol ratio below median value, whereas 47 deaths (29%) occurred in recipients with ratio above the median (P < .001). Log-rank test showed significantly higher mortality in the group with monocyte-to high density lipoprotein cholesterol ratio higher than median (P = .001). In the multivariate Cox model, delayed graft function, duration of dialysis, cold ischemia time, and monocyte-to-high-density lipoprotein cholesterol ratio group appeared as independent predictors of all-cause mortality. Conclusions: Monocyte-to-high-density lipoprotein cholesterol ratio before kidney transplant seems to affect survival independently in deceased donor kidney transplant recipients.Publication Relapsing urinary tract infection due to rectourethral fistula in a renal transplant recipient(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2015-01-01) Oruç Koç, Ayşegül; Ersoy, Alparslan; ERSOY, ALPARSLAN; Tıp Fakültesi; Nefroloji Ana Bilim Dalı; AAH-5054-2021Objectives: Urinary tract infection (UTI) is the most common cause of bacterial infection in renal transplant recipients. It occurs frequently in the early period because of the high-dose immunosuppressive agents and urethral catheterizations. Relapsing UTI may lead to graft dysfunction and further evaluations have to be performed for predisposing factors. We report the case of a renal transplant recipient who presented with relapsing bacterial UTI due to a rectourethral fistula.Case: A 24-year-old male patient underwent a successful renal transplantation from a living donor on May 2008. He had a history of surgical intervention for anal atresia and rectourethral fistula. He was hospitalized five times because of relapsing bacterial UTI after transplantation. We investigated the presence of an anatomical abnormality and found a rectourethral fistula. After the surgical repair of the fistula the UTI did not relapse.Conclusion: Relapsing infections are not uncommon and anatomical abnormalities can lead to relapsing UTI in transplant recipients. Further investigations must be performed regarding the factors that might contribute to the development of UTIs in the presence of relapsing UTI.Publication Pregnancy and kidney transplantation: A single-center experience(Aves, 2022-07-01) Ayar, Yavuz; Sayılar, Emel Işıktaş; Demir, Bilge Cetinkaya; ÇETİNKAYA DEMİR, BİLGE; ERSOY, ALPARSLAN; OCAKOĞLU, GÖKHAN; YILDIZ, ABDULMECİT; ORUÇ, AYŞEGÜL; Tıp Fakültesi; Jinekoloji ve Doğum Ana Bilim Dalı; 0000-0003-4607-9220; 0000-0002-1114-6051; 0000-0002-0342-9692; 0000-0001-6845-9991; AAH-5180-2021; AAH-4002-2021Objective: The possibility of pregnancy increases with kidney transplantation in patients with chronic kidney disease. However, graft dysfunction, risk of fetal growth retardation, and fetal anomaly should be monitored closely. In this study, renal and obstetric outcomes were analyzed in pregnant kidney recipients who were followed in our center.Methods: We analyzed 140 reproductive-aged patients who underwent renal transplantation between January 2009 and May 2015, and clinical and laboratory data were evaluated retrospectively.Results: Twenty-four patients became pregnant (17.1%). In pregnant group, median age was significantly lower than nonpregnant group (P =.014). The median age of pregnant group at the time of transplantation was also significantly lower than non-pregnant patients (P <.001). The rate of pregnant patients was 66.7% in 18-25 year age group (P =.008). The rate of urinary tract infection in non-pregnant group was higher than pregnant group (P =.03). Live birth rates were 83.3% and 45.8% of those whose birth weight was higher than 2500 g. The increased level of daily urinary proteinuria and the time from diagnosis of renal failure to transplantation had significant effect on pregnancy (odds ratio = 13.81;95% CI: 2.06-92.45; P =.007 and odds ratio = 3.25;95% CI: 1.11-9.48; P =.031, respectively). Low serum creatinine level had significant protective effect (odds ratio = 0.001; 95% CI: 0-0.30, P =.018). The patients in 18-25 age group were 48.39 times more eligible for pregnancy compared to those in >35 age group (odds ratio = 48.39; 95% CI: 1.26-1860.72; P =.037). Rejection episodes were observed in 1 of pregnant women and 11 of non-pregnant women (P >.05).Conclusion: Pregnancy is possible in kidney transplant recipients of reproductive age. Calcineurin inhibitors and azathioprine seem to be safe. Maternal age, low-serum creatinine, and urinary proteinuria affect pregnancy. The close monitoring of renal function and fetal parameters is very important.