Person: COŞKUN, HAMDİ HAKAN
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COŞKUN
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HAMDİ HAKAN
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Publication Inflammatory complications of vocal fold injection with hyaluronic acid: A multiinstitutional study(TUBİTAK, 2021-01-01) Enver, Necati; Azizli, Elad; Akbulut, Sevtap; Tatar, Emel Cadalli; Yelken, Muhammed Kursad; Ozturk, Kayhan; Birkent, Ahmet Hakan; Buyukatalay, Zahide Ciler; Ozgursoy, Ozan Bagis; Oguz, Haldun; Coskun, Hakan; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; 0000-0002-0881-1444Background/aim: This study aimed to assess the inflammatory adverse reactions of vocal fold injection laryngoplasty with hyaluronic acid.Materials and methods: This study was a retrospective chart review of patients who underwent vocal fold injection augmentation with HA injection from January 2005 to September 2016 in nine different institutions. Demographic data, indication for injection, injection techniques, types of injection material, settings of procedure, and complications were reviewed. The types of complication, onset time, and management of complications were also noted.Results: In all, 467 patients were identified. The majority of patients had been injected under general anesthesia (n = 382, 84.7%). For injection material, two different types of hyaluronic acid were used: hyaluronic acid alone or hyaluronic acid with dextranomer. Complications occurred in nine patients (1.9%). The majority of complications were inflammatory reactions (n = 7, 1.47%). Main symptoms were dysphonia and/or dyspnea with an onset of 0 h to 3 weeks after the hyaluronic acid injection. Three patients were hospitalized, one of which was also intubated and observed in the intensive care unit for 24 h. Systemic steroids and antibiotics were the main medical treatment in the majority of cases. There was no statistical difference in complication rates between patients who received hyaluronic acid and those who received hyaluronic acid with dextranomer (P = 0.220).Conclusion: Hyaluronic acid can be considered as a safe substance for the injection of vocal folds with a low risk of inflammatory reaction.Publication Our results of fine-needle aspiration cytology of the head and neck masses excluding thyroid: Experience of Uludag(Galenos Yayıncılık, 2005-06-01) Dilber, Muhammet; Erisen, L.; Yerci, Ömer; Coşkun, Hakan; Basut, O.; Onart, Selçuk; Hızalan, İbrahim; Dilber, Muhammet; Erisen, L.; YERCİ, ÖMER; COŞKUN, HAMDİ HAKAN; Basut, O.; Onart, Selçuk; Hızalan, İbrahim; Tip Fakültesi; Kulak Burun Boğaz Ana Bilim Dalı; 0000-0002-0881-1444; CMI-5616-2022; ETY-7294-2022; EIS-5114-2022; DVC-7511-2022; CFJ-8210-2022; FQP-9099-2022; EZI-7933-2022Objectives: To evaluate the results of fine needle aspiration cytology (FNAC) used for extra-thyroidal masses of the head and neck in our institution.Methods: The results of 542 FNAC done on 487 patients, referred to our university hospital in five years period from 1998 to 2002, with extra-thyroidal masses of the head and neck were evaluated retrospectively by examining the files in the department of pathology. FNAC results of 127 patients, who also had permanent biopsy results, were evaluated according to age and localization of the pathology. The rates of accuracy, specificity, sensitivity, positive and negative predictive values were calculated.Results: During this period, 62.5% of the all FNACs were done on head and neck masses, and 12.9% of those to extra-thyroidal pathologies. Accuracy rates of FNAC were 94.3% for congenitaldevelopmental pathologies, 89.4% for infectious-inflammatory pathologies (93.5% for specific infections), and 83.7% for neoplastic pathologies (85.9% for malignancies). There were no statistically significant differences between the accuracy rates of FNAC according to patient's age and localization of the pathology. False negative rate was higher than false positive rate in malignant lesions. Correct diagnostic rate based on the cellular differentiation in the malignant pathologies was 50%.Conclusion: 1. FNAC has a high accuracy rate for head and neck masses. 2. FNAC should be first step of pathological examination in all head and neck masses with an intact overlying mucosa or skin. 3. There are no differences between the accuracy rates of the FNAC of the childhood or the adulthood period. 4. There are no differences between the accuracy rates of the FNAC of the pathologies of the neck or the salivary glands. 5. Clinically, FNAC should only be used as a guide for preliminary diagnosis, especially in malignant pathologies. Final treatment decision should not be made according to the results of FNAC and tissue biopsy should be obtained before definitive treatment.Publication The incidence of thyroid gland invasion in advanced stage laryngeal cancers with emphasis on risk factors and its impact on survival(Elsevier, 2021-07-01) Aslıer, Mustafa; Uçurum, Bahar Ezgi; Kaya, Hilmi Cem; Coşkun, Hakan; ASLIER, MUSTAFA; KAYA, HİLMİ CEM; UÇURUM KANTARCI, BAHAR EZGİ; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı; 0000-0003-3670-4651; 0000-0002-0881-1444; CCA-0193-2022; JJJ-8575-2023; GEH-1871-2022; DVC-7511-2022Publication Treatment results and postoperative complications of single-stage tracheal resection in adolescent patients with post-intubation tracheal stenosis, compared to adults(Galenos Yayıncılık, 2022-03-01) Aslıer, Mustafa; Yıldırım, Muhammed Furkan; Coşkun, Hakan; ASLIER, MUSTAFA; YILDIRIM, MUHAMMED FURKAN; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; Kulak Burun Boğaz, Baş Boyun Cerrahisi Ana Bilim Dalı; 0000-0002-6117-9345; 0000-0002-0881-1444; 0000-0001-8257-0979; CCA-0193-2022; IRY-6058-2023; DVC-7511-2022Objective: The purpose of this study was to analyze the treatment outcomes and postoperative complications of tracheal resection in patients under the age of 19 years with post-intubation tracheal stenosis, and to compare the results with those of adults.Methods: Data were retrospectively retrieved from the medical records, including demographic characteristics. perioperative features, any postoperative complications and follow-up statuses of the patients. Treatment results and postoperative complications were compared between adolescent and adult groups.Results: Overall, anastomotic and non-anastomotic complication rates in the adolescent group and the adult group were 40%, 40%, 10% and 63%, 44.4%, 33.3%, respectively. Overall treatment success rates based on tracheostomy tube and tracheal stent free status were 90% and 92.6% in adolescent and adults, respectively.Conclusion: Treatment success rates and incidence of anastomotic complications were found similar in patients under the age of 19 years and adult patients who underwent single-stage tracheal resection and end to end anastomosis for treatment of post-intubation tracheal stenosis.Publication The prognostic value of thyroid gland invasion in locally advanced laryngeal cancers(Taylor, 2021-08-16) Aslıer, Mustafa; Uçurum, Bahar Ezgi; Kaya, Hilmi Cem; Coşkun, Hakan; ASLIER, MUSTAFA; UÇURUM KANTARCI, BAHAR EZGİ; KAYA, HİLMİ CEM; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; Kulak Burun Boğaz Baş Boyun Cerrahisi Ana Bilim Dalı; 0000-0001-8257-0979; 0000-0003-0786-4453; 0000-0003-3670-4651; 0000-0002-0881-1444; ABH-1328-2021; KHB-5653-2024; GDF-8132-2022; GEH-1871-2022; DVC-7511-2022Background Locally advanced laryngeal cancers can spread to the thyroid gland by direct invasion of cricothyroid membrane. The prevalence of thyroid gland invasion (TGI) and the predictive factors of TGI were well described in literature. However, the association of TGI with survival was undetermined yet. Objectives The aim of this study is to analyze the effects of TGI on survival rates in patients with locally advanced laryngeal cancer. Materials and methods Medical records of 91 patients who underwent total laryngectomy with thyroidectomy were retrospectively reviewed. Demographical, clinical, and histopathological characteristics of the patients were noted. Kaplan-Meier test was used for survival analysis. Results Histopathology reports revealed the prevalence of TGI as 14.3% (13/91). Survival analyses showed that TGI did not affect recurrence free (p = .078) and overall (p = .080) survival rates. Conclusions Thyroid gland invasion is one of the characteristic features of locally aggressive laryngeal tumors. In this study, TGI is not a statistically significant prognostic factor that has impact on survival of the patients with locally advanced laryngeal cancer.Publication Laryngoscopic examination during the COVID-19 pandemic: Turkish voice speech and swallowing disorders society and Turkish professional voice society recommendations(Galenos Yayıncılık, 2020-09-15) Çobanoğlu, H. Bengü; Enver, Necati; Akbulut, Sevtap; Atmış, E. Özlem; Birkent, Hakan; Büyükatalay, Çiler; Demirhan, Erhan; Denizoğlu, İlter; Hasımlı, Ramil; Korkmaz, Müge Özçelik; Özgürsoy, Selmin Karataylı; Öztürk, Kayhan; Paltura, Çeki; Şirin, Seher; Tatar, Emel Çadallı; Tüzüner, Arzu; Yelken, Kürşat; Coşkun, H. Hakan; Oğuz, Haldun; Öz, Ferhan; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; Kulak Burun Boğaz, Baş Boyun Cerrahisi Ana Bilim Dalı; 0000-0002-0881-1444; EQK-3127-2022COVID-19 is highly transmissible and spreads rapidly in the population. This increases the occupational risk for health care workers. In otolaryngology clinic practice, patients with upper respiratory tract infection symptoms are common. Also, routine head and neck examinations such as oral cavity examination, nasal/nasopharyngeal examination, or video laryngostroboscopic evaluation are highly risky because of the aerosol formation. To emphasize this issue, two leading otolaryngology organizations in Turkey; 'Voice Speech and Swallowing Disorders Society', and 'Professional Voice Society' gathered a task force. This task force aimed to prepare a consensus report that would provide practical recommendations of the safety measurements during routine clinical care of laryngology patients. To fulfill this, universal aim, on the 2nd and 9th of May 2020, two web-based meetings were conducted by 20 expert physicians. This eighteen items list was prepared as an output.Publication Comparison of clinical results in nasal tip augmentation either via face to face or back to back technique with autogenous auricular conchal cartilage(Lippincott Williams & Wilkins, 2015-06-28) Şahin, Murat Sertan; Kasapoğlu, Fikret; Demir, Uygar Levent; Özmen, Ömer Afşin; Coşkun, Hakan; Basut, Oğuz; Sahin, Murat Sertan; KASAPOĞLU, FİKRET; DEMİR, UYGAR LEVENT; ÖZMEN, ÖMER AFŞIN; COŞKUN, HAMDİ HAKAN; BASUT, OĞUZ İBRAHİM; Tıp Fakültesi; Kulak Burun Boğaz Cerrahisi Ana Bilim Dalı; 0000-0002-4718-0083; 0000-0002-9698-0546; 0000-0002-0881-1444; A-1452-2019; AAI-3877-2021; BBC-2978-2021; CNQ-7672-2022; DVC-7511-2022; CFJ-8210-2022Objective:To compare the objective and subjective findings between patients who underwent nasal tip augmentation surgery via two different methods using autogenous auricular conchal cartilage.Materials and Methods:This study included the data of 21 patients who underwent nasal tip augmentation surgery. The patients were randomly divided in two groups according to the technique used to form a double layer columellar strut graft; either face to face (group 1) and back to back (group 2). All patients were assessed via nasal obstruction symptom evaluation scale (NOSE) and via acoustic rhinometry and rhinomanometry at preoperative and postoperative 1st and 6th months.Results:There was statistically significant improvement in symptom score in both patient groups with no difference inbetween. Total nasal resistance decreased nonsignificantly at the end of 6th month in both groups; 13.1Pa/cm(3) to 8.6Pa/cm(3) and 10.3Pa/cm(3) to 9.5Pa/cm(3) respectively. There was no significant increment in MCA values for both groups except left MCA1.Conclusions:We achieved good results in tip augmentation via both techniques. An autogenous conchal cartilage is a good alternative to replace lacking caudal septal cartilage. It provides safe and stable support to the nasal tip. However, further comprehensive studies with larger sample size and long follow-up are required to elucidate any difference between these two techniques.Publication Lesions that mimic malignant tumors in nasopharyngeal biopsies: Case series of 10 years(Sage Publications Ltd, 2021-03-17) Özşen, Mine; Saraydaroğlu, Özlem; Yirmibeş, Selin; Coşkun, H. Hakan; ÖZŞEN, MİNE; SARAYDAROĞLU, ÖZLEM; Yirmibeş, Selin; COŞKUN, HAMDİ HAKAN; Tıp Fakültesi; Patoloji Ana Bilim Dalı; 0000-0002-5771-7649; 0000-0002-8211-6175; AAI-1609-2021; DPZ-1981-2022; EBH-3474-2022; EQK-3127-2022Introduction: Lesions mimicking malignancies in the nasopharynx are frequently seen in adult patients. These include inflammatory, metaplastic, and cystic lesions. We aimed to draw attention to rare tumor-like lesions that can be confused with malignancies and cause diagnostic difficulties clinically and radiologically. Methods: A total of 538 patients who underwent nasopharyngeal biopsy in our center between January 2010 and June 2020 were evaluated. Patient information was obtained from patient files and evaluated retrospectively. Results: A total of 19 of the 538 patients had tumor-like lesions that were included in the study. Granulomatous inflammation was present in seven cases, oncocytic metaplasia in four cases, benign cyst in five cases, fungal infection in two cases, and immunoglobulin G4-related disease in one case. Conclusions: The nasopharynx is a region where various lesions can be seen. Some lesions form tumor-mimicking mass effect, cause increased thickness, and lead to increased metabolic activity in positron emission tomography-computed tomography that create the illusion of a malignant tumor and histopathologic verification is crucial. We aimed to present these rare tumor-like lesions that should be kept in mind in the differential diagnosis.Publication The efficiacy of sternocleidomastoid muscle flap on frey's syndrome via a novel test: Galvanic skin response(Springer India, 2014-01-01) Demirci, Uğur; Basut, Oğuz; Noyan, Behzat; Demir, Uygar Levent; Özmen, O. Afşin; Kasapoğlu, Fikret; Coşkun, H. Hakan; Onart, Selçuk; Demirci, Uğur; BASUT, OĞUZ İBRAHİM; Noyan, Behzat; DEMİR, UYGAR LEVENT; ÖZMEN, ÖMER AFŞIN; KASAPOĞLU, FİKRET; COŞKUN, HAMDİ HAKAN; Onart, Selçuk; Tıp Fakültesi; Fizyoloji Ana Bilim Dalı; 0000-0002-9698-0546; A-1452-2019; AAI-3877-2021; GWW-4604-2022; CFJ-8210-2022; FRE-9096-2022; EQK-3127-2022; FQP-9099-2022; CNQ-7672-2022The aim of this study was to evaluate the effects of sternocleidomastoid (SCM) muscle flap on preventing Frey's syndrome by using, Galvanic skin responses (GSR). Fourty-three patients who underwent superficial parotidectomy were randomly divided into two groups and their GSR were recorded. SCM muscle flap was applied over the surgical area only in one group. Six months after the surgery, GSRs were remeasured. In addition, the patients completed a questionnaire regarding their complaints about clinical Frey's syndrome. Four patients had symptoms of clinical Frey's syndrome. Postoperative GSR measurements revealed no significant difference between two sides in flap group (p = 0.426) but higher in without flap group (p = 0.003). The patients with clinical Frey syndrome had significantly higher GSR values than the remaining patients. The SCM muscle flap was an effective method in preventing Frey's syndrome. Moreover, GSR test was highly sensitive and specific for diagnosis.Publication Unique presentation of adenoid cystic carcinoma in postcricoid region: A case report and review of the literature(Springer, 2011-12-01) Saraydaroğlu, Özlem; Coşkun, Hakan; Kasap, Mehtap; SARAYDAROĞLU, ÖZLEM; COŞKUN, HAMDİ HAKAN; Kasap, Mehtap; Tıp Fakültesi; Patoloji Ana Bilim Dalı; 0000-0002-0881-1444; AAH-9701-2021; DVC-7511-2022; FDC-3047-2022Malignant tumors of minor salivary glands are uncommon, representing only 2-4% of all head and neck malignancies. In the larynx, minor salivary gland tumors rarely occur and constitute less than 1% of laryngeal tumors. Most of the minor salivary gland tumors arise in the subglottis; however, they can also occur in the supraglottis in the false vocal cords, aryepiglottic folds, and caudal aspect of the epiglottis. The most common type of malignant minor salivary gland tumor is adenoid cystic carcinoma. In the last 20 years, only 40 cases of adenoid cystic carcinoma arising in variable locations of the larynx have been reported in the English language literature. We present a case of adenoid cystic carcinoma of the larynx arising in the inter-arytenoid and postcricoid region in a 54-year-old woman. To our knowledge, this is the first case of adenoid cystic carcinoma arising in this particular region of the larynx.