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HACIMUSTAFAOĞLU, MUSTAFA KEMAL

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HACIMUSTAFAOĞLU

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MUSTAFA KEMAL

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Now showing 1 - 10 of 102
  • Publication
    Enterococcal infections in children: Results of a 8 year study
    (Aves Yayıncılık, 2010-12-01) Çelebi, Solmaz; Hacımustafaoğlu, Mustafa; Demiral, Meliha; Sınırtaş, Melda; Demirtaş, Fatih; İpek, Kezban; Bayram, Gönül; ÇELEBİ, SOLMAZ; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Demiral, Meliha; Sınırtaş, Melda; Demirtaş, Fatih; İpek, Kezban; Bayram, Gönül; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Enfeksiyon Hastalıkları Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; 0000-0003-4646-660X; JHN-1091-2023; CTG-5805-2022; EVQ-9906-2022; DSE-4824-2022; CNC-2567-2022; CUO-6602-2022; EKC-9935-2022
    Objective: Enterococci have become a leading cause of nosocomial infection. These microorganisms are normal inhabitants of the human gastrointestinal tract. The aim of this study was to evaluate the enterococcal infection in children.Material and Methods: All patients with enterococcal infection between January 1, 2000 and December 31, 2007 were included in this study. Our study is a retrospective analysis of prospectively collected data. American Centers for Disease Control and Prevention criteria were used as standard definitions for nosocomial infections.Results: Enterococcus spp. infections were diagnosed in 164 of the 15.558 patients hospitalized in our center between January 1, 2000 and December 31, 2007 (overall incidence, 10.5 per 1,000 admissions). During the study period, a total of 209 Enterococcus spp. isolates were recovered from sterile body site cultures. Seventy-seven percent of enterococcal infections were nosocomial. The mean age of patients was 53.1 +/- 61.5 months (9 days-17 years) and 56% were male. The most common species of enterococci causing clinical infection were Enterococcus faecalis (55.5%), Enterococcus faecium (42.1%) and Enterococcus durans (2.4%). Most of the Enterococcus spp. (44.5%) were isolated from urine, followed by blood (19.5%), peritoneal fluid (14.6%), cerebrospinal fluid (12.1%) and catheter segment (4.8%). Vancomycin resistance was seen in 2.4 percent of Enterococcus spp., all of which were E. faecium. The most frequently seen enterococcal infections were urinary tract infections (32.3%), neonatal sepsis (22%), sepsis (14.6%), peritonitis (11.5%) and shunt meningitis (10.3%). Previous therapy with broad-spectrum antibiotics, underlying disease and prolonged hospitalization were commonly seen in patients with enterococcal infections. The mortality rate was found as 3.6% of all children with enterococcal infections.Conclusions: The two most common species of enterococci causing clinical infection were E. faecalis (55.5%) and E. faecium (42.1%). The most frequently enterococcal infections were urinary tract infections (32.3%), followed by neonatal sepsis (22%).
  • Publication
    Conjugated pneumoccoccal vaccines
    (Aves Yayıncılık, 2011-06-01) Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlıkları ve Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon ve Hastalıkları Bilim Dalı; 0000-0003-4646-660X; CTG-5805-2022
  • Publication
    How should we use magistral drugs in the treatment of scabies in babies and children?
    (Aves Yayıncılık, 2023-12-01) Aksoy, Fatma Dilşad; Hacımustafaoğlu, Mustafa Kemal; AKSOY, FATMA DİLŞAD; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon Hastalıkları Bilim Dalı.; 0000-0001-6128-5925; 0000-0003-4646-660X; DUC-0213-2022; CTG-5805-2022
  • Publication
    Evaluation of children with tuberculosis: A 10-year retrospective study
    (Galenos Publishing House, 2022-12) Yeşil, Edanur; Sezer, Çisel; Çelebi, Solmaz; Turan, Cansu; Bülbül, Beyhan; Hacımustafaoğlu, Mustafa; SEZER, ÇİSEL; ÇELEBİ, SOLMAZ; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı; 0000-0002-3928-3453; 0000-0002-3536-0263; 0000-0003-4646-660X; FVE-4013-2022; JHN-1091-2023; CTG-5805-2022
    Introduction: Childhood tuberculosis is a perspective that adult tuberculosis is not well controlled in the community. In this study, it was aimed to evaluate the epidemiological and clinical data of the cases we followed up with the diagnosis of tuberculosis.Materials and Methods: The clinical data of the cases who admitted to the Pediatric Infection Clinic and Outpatient Clinic of our hospital between 2010 and 2020 and were diagnosed with tuberculosis were retrospectively analyzed. Approval for the study was obtained from the Ethics Committee of Uludag University Medical Faculty with the decision no. 2020-5/3.Results: The mean age of 175 cases was 125 +/- 66,038 (median 132, 3-216) months, and 51% were female. 88% of the cases (n=154) live in Bursa and the majority of the admissions are from Osmangazi (n=41, 23.4%), Yildirim (n=40, 22.9%), Inegol (n=20, 11.5%) and Nilufer (n=19, 10.9%). Pulmonary tuberculosis was seen in 55% (n=96) of the cases, extrapulmonary tuberculosis in 42% (n=74), and pulmonary and extrapulmonary tuberculosis in 3% (n=5). 25.7% (n=45) of all cases had a history of contact with tuberculosis. 6.3% (n=11) of the cases had a history of taking prophylaxis before. Cough in 46% (n=81) of cases, fever in 29% (n=50), weight loss in 14% (n=24), night sweats in 13% (n=22), 5% (n=8) had complaints of hemoptysis. The mean sedimentation value of the cases was 36 +/- 28.85 (median 27. 5-140) mm/hour, and the mean CRP value was 16 +/- 41.94 (median 1. 1-258) mg/L. The tuberculin skin test was positive in 65% (n=114) of the cases. Mycobacter ARB (acid-resistant bacillus) was positive in 19% (n=27) and culture was positive in 18% (n=25) of the cases evaluated microbiologically (n=142). PCR was positive in 45% (n=47) of the 104 cases in which mycobacterial PCR was examined. Side effects were observed in 11% of the cases, and hepatotoxicity was observed most frequently (n=11, 6.3%). One patient died in the seventh month of treatment due to complications related to cystic fibrosis.Conclusion: Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis and may result in mortality if left untreated. In this study, culture positivity was found to be 18%, and the most common side effect was hepatotoxicity.
  • Publication
    Fever; definitions in clinical practice
    (Aves Yayıncılık, 2018-03-01) Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; CTG-5805-2022; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon Hastalıkları Bilim Dalı; 0000-0003-4646-660X
  • Publication
    The impact of the opening of the schools on covid-19 epidemiology
    (Aves Yayincilik, Ibrahim Kara, 2020-12-01) Bülbül, Beyhan; BÜLBÜL, BEYHAN; Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı; 0000-0002-5720-1212; 0000-0003-4646-660X
  • Publication
    X-ray-evaluation
    (Aves Yayincilik, Ibrahim Kara, 2008-03-01) Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Çelebi, Solmaz; ÇELEBİ, SOLMAZ; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; 0000-0003-4646-660X; AAI-2303-2021
  • Publication
    Asymptomatic congenital cmv newborn who failed unilateral hearing screening; shall we give treatment?
    (Aves Yayıncılık, 2022-03-01) Bülbül, Beyhan; Hacımustafaoğlu, Mustafa; BÜLBÜL, BEYHAN; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon Hastalıkları Bilim Dalı.; 0000-0002-5720-1212; 0000-0003-4646-660X; GAX-3172-2022; CTG-5805-2022
  • Publication
    Evaluation of risk and prognostic factors in neonatal meningitis
    (Galenos Yayınevi, 2023-04-01) Parlakay, Gülşah; Çakır, Salih Çağrı; Dorum, Bayram Ali; Özkan, Hilal; Çelebi, Solmaz; Hacımustafaoğlu, Mustafa; Köksal, Nilgün; Parlakay, Gülşah; ÇAKIR, SALİH ÇAĞRI; Dorum, Bayram Ali; ÖZKAN, HİLAL; ÇELEBİ, SOLMAZ; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Köksal, Nilgün; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Neonatoloji Bilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon Hastalıkları Bilim Dalı.; 0000-0001-5761-4757; 0000-0002-2823-8454; 0000-0003-4646-660X; HJZ-4508-2023; A-5375-2017; JJW-4932-2023; JJY-3921-2023; JHN-1091-2023; CTG-5805-2022; JGS-7600-2023
    Introduction: Neonatal meningitis is one of the important causes of mortality and morbidity in newborns. In this study, it was aimed to examine the microbiological factors, biochemical and clinical characteristics of neonatal meningitis cases, to reveal the risk factors, and to investigate the effect on the morbidities associated with meningitis in the first year of life.Materials and Methods: The files of patients diagnosed with meningitis in the level 3 Neonatal Intensive Care Unit between January 2010 and December 2015 were retrospectively analyzed.Results: There were 118 patients diagnosed with meningitis. The median gestational age of the patients was 32 weeks (24-40 weeks), and the median birth weight was 1987 grams (690-5020 grams). Most of the meningitis patients (n=106, 90%) were with late sepsis. The diagnosis day of those with poor prognosis was found to be greater [9.7 (2-28) days to 15.5 (3-138) days, p=0.03]. Cerebrospinal fluid (CSF) leukocytes were significantly higher in term babies with abnormal cranial magnetic resonance imaging (MRI) findings (p=0.037) and loss in hearing tests (p=0.045). CSF sugar levels were significantly lower in preterm babies with neuromotor retardation (p=0.001), history of seizures (p=0.003), abnormal cranial MRI findings (p=0.008) and hearing loss (p=0.005).Conclusion: In the long term, a significant number of cases with neonatal meningitis have neuromotor retarda-tion and hearing problems. Factors that can be used as predictors for poor neurological development; late-onset day, increased CSF leukocyte in all babies, and decreased CSF sugar in preterm babies.
  • Publication
    Threat culture/Questions
    (Aves Yayıncılık, 2007-03-01) Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı Hastalıkları Anabilim Dalı/Çocuk Enfeksiyon Hastalkları Bilim Dalı; 0000-0003-4646-660X; CTG-5805-2022