Person: TÜLÜMEN ÖZTÜRK, RAZİYE
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TÜLÜMEN ÖZTÜRK
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RAZİYE
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Publication Venom allergy in Turkish beekeepers and risk factors for systemic reaction(Wiley, 2015-09-01) Ediger, Dane; Terzioğlu, Kadriye; Öztürk, Tülümen Raziye; EDİGER, DANE; Terzioğlu, Kadriye; TÜLÜMEN ÖZTÜRK, RAZİYE; Tıp Fakültesi; 0000-0002-2954-4293; AAE-9142-2019; CGN-8618-2022; JLI-9749-2023Publication Hypersensitivity reaction due to oral methylprednisolone in a patient with nonsteroidal anti-inflammatory drug-exacerbated respiratory disease(Bilimsel Tip Yayinevi, 2019-01-01) Terzioğlu, Kadriye; Öztürk, Raziye Tulumen; TÜLÜMEN ÖZTÜRK, RAZİYE; Durmus, Eda; Ediger, Dane; EDİGER, DANE; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; 0000-0001-9503-661X; 0000-0002-2954-4293; AAE-9142-2019Hypersensitivity reactions caused by corticosteroids are rarely seen, despite widespread use of these medications. Sensitization to corticosteroids can occur through many routes such as nasal, aerosol, parenteral, oral and topical. Delayed allergic reactions may be observed after topically applied glucocorticoids, but IgE-mediated type 1 (immediate) allergic reactions, which occur after systemic application of glucocorticoids, are very rare. When case-based publications were examined, it was noticed that corticosteroid-associated IgE-mediated type 1 hypersensitivity reactions were more common in patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory diseases (NERD). We present a 32-year-old patient with nonsteroidal anti-inflammatory drug-exacerbated airway disease and a hypersensitivity reaction due to methylprednisolone.Publication How physicians approach hereditary angioedema: A single center study(Lippincott Williams & Wilkins, 2022-10-01) Terzioğlu, Kadriye; Ediger, Dane; Özdemir, Ebru; Tulumen Öztürk, Raziye; Doğan, Fatma Oflu; Sancar, Özgür; Terzioğlu, Kadriye; EDİGER, DANE; Özdemir, Ebru; TÜLÜMEN ÖZTÜRK, RAZİYE; Doğan, Fatma Oflu; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; İmmünoloji ve Alerji Hastalıkları Bilim Dalı; CGN-8618-2022; AAE-9142-2019; HGF-0700-2022; GDN-2707-2022; IBV-5646-2023Background: Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by C1-inhibitor deficiency. It is characterized by recurrent attacks of cutaneous and upper respiratory tract swelling, and abdominal pain due to mucosal edema. Early detection and treatment prevent unnecessary interventions, improves quality of life, and prevents potentially fatal attacks. Objective: The present study aims to investigate physicians level of knowledge and awareness regarding HAE. Methods: A questionnaire about HAE was applied to 393 physicians from a university hospital. Participants were requested to choose one or several answers to multiple-choice questions. Results: Seven and three tenths percent of study participants stated to have never heard of HAE. Twenty-seven physicians (7.4%) chose the exact correct answers regarding diagnostic tests, and 2 (0.8%) chose the exact correct answers regarding emergency management. A composite of internists, pediatrists and emergency medicine specialists had a significantly higher mean score than other physicians ( p = 0.047). Physicians from internal medical sciences scored significantly higher than physicians from surgical medical sciences ( p = 0.022). Conclusion: The present study reveals that physician awareness about HAE is low, and physicians misdiagnose HAE attacks as histaminergic angioedema attacks, and therefore provide ineffective treatment. Although HAE is a rare disease, physician awareness must be increased, because early diagnosis and effective treatment are vital for the patients.Publication Venom allergy, risk factors for systemic reactions and the knowledge levels among Turkish beekeepers(Lippincott Williams & Wilkins, 2018-04-01) Ediger, Dane; Terzioğlu, Kadriye; Öztürk, Raziye Tulumen; EDİGER, DANE; Terzioğlu, Kadriye; TÜLÜMEN ÖZTÜRK, RAZİYE; Tıp Fakültesi; Göğüs Hastalıkları Ana Bilim Dalı; İmmünoloji ve Alerji Hastalıkları Bilim Dalı; 0000-0002-2954-4293; AAE-9142-2019; CGN-8618-2022; JLI-9749-2023Background: Allergic reactions developing after bee sting can be severe and life-threatening. According to epidemiological data, serious systemic reactions range between 1.2%-3%, and this is 2-3 times higher (6%) in beekeeping. In different beekeepers' populations, risk factors of systemic reactions have been investigated and diverse results have been found.Objective: The aim of this study is to evaluate the level of knowledge of beekeepers about venom allergy, epidemiological data, systemic reaction rates, risk factors for systemic reactions, and the rate of emergency admissions after bee sting.Methods: With the collaboration of Uludag University Beekeeping Development Research Center and Beekeepers Association, a questionnaire consisting of 19 questions was applied to 242 beekeepers in Bursa and Yalova. Two hundred twenty-one beekeepers who completed the questionnaire were involved in the study.Results: The mean age of the beekeepers was 49.9 years range, 18-75 years). The systemic reaction to bee sting in beekeepers was 37.6%. Allergic rhinitis was found to be a risk factor for systemic reaction. Although 80% of the beekeepers recognized that bee venom could be lethal, only 60% of the beekeepers were aware of immunotherapy, and only 30% were aware of the adrenaline auto-injector drug.Conclusion: Similar to previous studies, we found that the systemic response to the bee sting in beekeepers was higher compared to normal population. Considering the occupational exposure to bee venom and thus higher risk, the awareness of venom allergy in this high risk population was low, and they were poorly informed about the treatment options.