2022 Cilt 22 Sayı 1

Permanent URI for this collectionhttps://hdl.handle.net/11452/27595

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Determination of anti-urease activity of propolis from the Marmara region of Turkey
(Bursa Uludağ Üniversitesi, 2022-03-01) Can, Zehra; Kara, Yakup; Kolaylı, Sevgi; Çakmak, İbrahim; Uludağ Üniversitesi/Ziraat Fakültesi/Hayvan Bilimleri Bölümü.; 0000-0002-8000-5770
Propolis is a natural product collected by honeybees from plants especially flowers and buds by mixing with wax and resin and used for many purposes in hive. It is known that propolis has been used in the treatment of various diseases in traditional medicine for many years and has biological activities such as antioxidant, antimicrobial, antiulcer, antitumor, anti-inflammatory. There is increasing interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thereby treat many gastric diseases. This study investigated various properties of raw propolis samples from the Marmara region of Turkey. Anti-urease activity was investigated in propolis samples. The anti-urease activity of IC50 values ranged from 1.110 to 5.870 mg/mL. As a result, it can be said that propolis extract is a good inhibitor that can be used in the treatment of H. pylori to improve human health.
Ecological niche modeling: An empirical study on apis mellifera population distribution
(Bursa Uludağ Üniversitesi, 2022-04-20) Öksüsüzoğlu, Dilşan; Aydın, Murat
Ekosistem çeşitliliğinde en önemli türlerden olan bal arısı, Apis mellifera türü dünya genelinde birçok bölgeye yayılım göstermiştir fakat iklim değişikliği sebebiyle yakın gelecekte sayılarının azalma tehdidi ile karşı karşıyadır. Bu nedenle iklimsel değişkenlerin bal arıları üzerindeki etkileri daha detaylı incelenmeli ve potansiyel negatif etki faktörleri belirlenmelidir. Bu çalışmada Birleşik Krallık, Hollanda, Fransa, Almanya ve Zambiya’da bulunduğu kaydedilen A. mellifera verileri iki farklı izdüşümü modeli yardımıyla şimdiki zaman ve gelecek tahminlerine yansıtıldı. Gelecek tahmininde Avrupa genelinde bal arılarında gözle görülür bir nüfus azalışı kaydedilirken Kuzey Amerika’da değişim, günümüze göre, çok azdı. Daha sonra PCA analiz yöntemi kullanarak 19 iklimsel değişken bir arada değerlendirildi ve günümüzden geleceğe büyüme oranları hesaplandı. Bu çalışma doğrultusunda genel olarak Avrupa’da gelecekte en çok değişiklik gösteren iklimsel değişkenlerin Kuzey Amerika’da gelecekte kritik bir değişikliğe uğramayacağı sonucuna ulaşıldı. Sonuç olarak, bu tür için yüksek orandaki nüfus azalışında etkili olan ve etkilerini yakın gelecekte Avrupa’da gösterecek olan değişkenler kışların şiddeti, en soğuk bölgenin ortalama sıcaklığı, yağış ve sıcaklık mevsimselliği olarak belirlendi.
Effects of royal jelly on obesity
(Bursa Uludağ Üniversitesi, 2022-04-14) Demirkaya, Aslihan; Celep, Adviye Gulçin Sağdiçoğlu
Obesity is a disease that affects people's quality of life and is a risk factor for some fatal diseases. Its prevalence is increasing in the world and the biggest factor is nutritional problems and a sedentary lifestyle. Royal jelly (RJ), a natural product for obesity, a preventable disease, has been the subject of various studies. RJ secreted by young honey bees (worker bees) is the only food source for the queen bee and the first three days of food for immature bees. Several studies have shown RJ's anti-obesity, antioxidant, anticarcinogenic, antimicrobial, and anti-inflammatory activities. In addition, RJ is seen as a promising functional food in the prevention of obesity and protection from its negative effects. This study is an examination of studies on the effects of RJ on obesity and its accompanying problems.
Green synthesis and biochemical properties of propolis based silver nanoparticles
(Bursa Uludağ Üniversitesi, 2022-03-25) Keskin, Merve; Kaya, Gülşen; Keskin, Şaban
Propolis is a substance collected by honey bees from different parts of plants. Honey bees store it in their hives in order to defend against different threats. Propolis is a bee-product rich in plant waxes, esters, fatty acids, volatile components and phenolic compounds. It`s rich phenolic content makes propolis a potential reducer for Ag+ to Ag. In this study, propolis-based silver nanoparticles were obtained using the green synthesis technique. It was determined that the obtained silver nanoparticles had a maximum absorbance at 425 nm and their sizes ranged from 67 to 75 nm. When the FT-IR data of propolis extract is examined, the band at 3200 cm-1 represents functional -OH groups, the band at 2919-2850 cm-1 represents C-H stretching, the band at 1634 cm-1 represents C=C, C=O or NH stretching, the band at 1508 cm-1 represents aromatic C=C stretching and the band at 1451 cm-1 originate from the C-H stretching of CH3, CH2, flavonoids and aromatic rings. Total phenolic content of propolis extract and silver nanoparticles was determined as 176.42±0.18 and 122.63±0.23 mg GAE/mL, respectively. IC50 value of P-AgNPs for α-amylase and α-glycosidase enzyme inhibition was defined as 47.08 ± 0.002 and 52.18 ± 0.001 µg/mL, respectively. Inhibition of α-Amylase and α-glycosidase is still a valid approach in the treatment of diabetes. The high inhibition effect of the obtained nanoparticles on the related enzymes shows that they have diabetes treatment potential. In addition, showing that cheap and abundant nanoparticles can be obtained by using propolis, this study may contribute to the development of new products containing nanoparticles that can be used in apitherapy applications.
Immunomodultatory effect of indonesian propolis in pregnant mice: A preliminary result
(Bursa Uludağ Üniversitesi, 2022-04-24) Fikri, Al Mukhlas; Sulaeman, Ahmad; Marliyati, Sri Anna; Fahrudin, Mokhamad; Handharyani, Ekowati
Propolis has been widely accepted to exhibit immunomodulatory activity. However, the activity during pregnancy has not been investigated yet. This study was a preliminary study that aimed to analyze the effect of several types of Indonesian propolis on the histological changes of maternal mice spleen. A total of 25 pregnant mice were divided into 5 groups, control (1% Tween 80) group, low (380 mg/kg) and high dose (1400 mg/kg) ethanol extract of South Sulawesi propolis groups, and low (380 mg/kg) and high dose (1400 mg/kg) water extract of Banten propolis groups. Propolis samples were administered daily during pregnancy. At day 18 of gestation, the mice were sacrificed to obtain spleen which was used for histological evaluation using hematoxylin and eosin staining. The number and diameter of white pulp were observed under the 10x magnifying of microscope. The results showed that all propolis extracts at low dose significantly increased the number of white pulp (p < 0.05). However, an increase in the diameter was found not significant in all propolis administered groups. This study suggests that Indonesian propolis may modulate maternal immune system.
May the honey bees sensitivity to earth’s magnetic field assist them for building?
(Bursa Uludağ Üniversitesi, 2022-01-09) Pokutsa, Alexander P.; Muzart, Jacques
A surprising D12 symmetry inside-hive constructions of honey bees were disclosed. The well established sensitivity of bees to the magnetic field led us to supposition that it may play a key role in steering of such regular architecture.
Palynological analysis, phenolic components and anti inflammatory activity of some bee pollens collected from the northeast region of Algeria
(Bursa Uludağ Üniversitesi, 2022-03-21) Mokhtari, Mohamed Badreddine; El Ouar, Ibtissem; Zeghina, Ibtissem; Tartouga, Maya Abir; Ghorab, Asma; Bahri, Laid; Bensouici, Chawki
Bee pollen is multiplex blend of floral pollen and nectar agglutinated by bee salivary substances. It is famously known for being high in proteins, carbs, lipids, vitamins, and phenolic compounds, among other physiologically dynamic components. Its composition fluctuates incredibly agreeing to both botanical origins and edaphoclimatic conditions. In this work, the botanical origin, the phenolic components and the anti-inflammatory activity in vivo of eight bee pollens intended for human consumption were taken from distinctive apiaries in Algeria’s northeast, were determined and compared. All samples were detected heterofloral based on the identification of forty pollen types belonging to 22 botanical families. Total phenolic contents varied between 752.94 ± 17.78 and 12247.06 ± 40.04 mg GAE/ 100g, while the total flavonoid contents ranged from 2680.55 ± 12.02 to 8506.94 ± 15.56 mg QE/ 100g, and the total flavonol contents were in the interval between 4978.87 ± 33.39 and 7903.75 ± 24.39 mg QE/ 100g. The obtained results showed that the bulk of the ethanolic extracts had a good anti-inflammatory activity. As a conclusion, all the aforementioned heterofloral bee pollen samples could significantly be a wealthy source of polyphenols with a potential anti-inflammatory activity.
Significance of hydroxymethylfurfural and melanoidins as products of maillard reactions in honey
(Bursa Uludağ Üniversitesi, 2022-04-15) Miranda, Ina Ramirez; Ordonez, Yolanda Moguel; Ancona, Dawid Betancur
Honey presents exceptionally favorable conditions for a non-enzymatic glycation of proteins or Maillard reaction (MR), which is a complex network of chemical reactions which is favored during processing and storage and that often influence the quality and acceptability of honey. One of the organic compounds produced in the intermediate stages of MR that has been the subject of several investigations and controversies, due to its relationship with adverse effects on human health, is 5- hydroxymethylfurfural (HMF), which has become an indicator of honey quality. Conversely melanoidins, polymeric molecules responsible for non-enzymatic browning and which have been related to beneficial effects due to the antioxidant and antibacterial properties of honey, are produced in the final stages of MR. The aim of this article is to provide a review on the formation as well as the positive and negative effects associated with the formation of HMF and melanoidins as MR products in honey.
Using geographical information systems and remote sensing to detect resin-rich areas for propolis production from apiaries
(Bursa Uludağ Üniversitesi, 2022-01-10) Amro, Abdulraouf Mohamed; Abou-Shaara, Hossam Farag
Propolis (bee glue) is considered among bee products with medicinal properties. The majority of plants in Egypt are field crops which cultivated by farmers. Such crops may supply bee colonies with nectar/pollen, but are not good sources for resin due to their short life cycles. This study aimed to explore potential sites for producing high amounts of propolis from bee colonies based on a remote sensing analysis. The study was performed on a Governorate with intensive agricultural activity in Egypt (Assiut Governorate). The methodology depended on isolating trees from the satellite image using unsupervised classification followed by supervised classification based on numerous geographical coordinates of trees. Trees were transferred into points, and then point density was calculated to classify the study location into classes according to density. Sites with the very high numbers of trees were especially recommended for producing propolis on a commercial scale by beekeepers. Giving more attention to propolis production can enhance the income of beekeepers and maximize the economic benefit from bee colonies.

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