2017 Cilt 15 Sayı 3

Permanent URI for this collectionhttps://hdl.handle.net/11452/8983

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    Evaluation of antiemetic therapy used for chemotherapy induced nausea and vomiting in children
    (Uludağ Üniversitesi, 2017) Emir, Suna
    Nausea and vomiting associated with chemotherapy is one of the important side effects of treatment in children with cancer. Despite the development of new antiemetic agents, there are still some problems in this regard in children. The combination of a 5-HT3 receptor antagonist plus a corticosteroid is usually used to prevent chemotherapy induced nausea and vomiting (CINV) in children receiving emetogenic chemotherapy. New antiemetic agents do not take part in the current pediatric guidelines. There is also no sufficient data on alternative agents in children with intractable vomiting. This review summarizes the CINV definitions in children, the classification of the antiemetic drugs as standard, newly available and optional drugs in children. Each drug category is discussed according to the mode of action, efficacy in different types of CINV, recommended dose and finally some suggestions for CINV in children.
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    Flash glucose monitoring experiences of the families of the patient with Type 1 diabetes mellitus
    (Uludağ Üniversitesi, 2017) Eren, Erdal; Tarım, Ömer; Tıp Fakültesi; Çocuk Endokrin Bilim Dalı
    Aim: Patients with type 1 diabetes and their families are increasingly interested in technological development in glucose monitoring. The comfort of frequently monitoring with flash glucose monitoring (Freestyle Libre/Abbott) is appealing although it is not commercially available yet in Turkey. In this study, we aimed to investigate the data obtained by this method as well as the experience, satisfaction, and the problems encountered by the families. Materials-Methods: A questionnaire was given to the families of diabetic patients by a web based program. The questions involved information about age, gender, last HbA1c, and duration of diabetes as well as information about the device. Repetitious answers, incomplete data, and patients above 18 years of age were not included. Results: Mean age of the 72 patients was 8.29 years and 42% was male. Mean duration of diabetes was 2.6 years and mean HbA1c was 7.27%. Freestyle Libre was used for 5.6 months (15 days-19 months). The families had heard about the device from internet (62%), friend (23.9%), doctor (9.9%), or relatives (4.2%). In response to confirmation of the results by finger stick measurement, 70.8% said sometimes, 27.8 frequently, 1.4% no. HbA1c was claimed to improve in 73.6%, and it did not change in 23.6%. 96% reported that the device made their life easier and 97% was willing to recommend it to other families. Conclusions: The families are in search to make glucose monitoring easier for their children. Although, they have some concerns about the reliability of the measurements at extremely high and low blood glucose levels, they are happy because it is easy and practical to use.