1988 Cilt 7 Sayı 1-2-3

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Koyunlarda nematod ve trematod enfeksiyonlarına albendazol'ün etkisi̇
(Uludağ Üniversitesi, 1988) Tınar, Recep; Coşkun, Şevki Ziya; Doğan, Hüsrev; Demir, Semra; Akyol, Volkan Ç.; Veteriner Fakültesi; Parazitoloji Ana Bilim Dalı
Albendazole at the doses of 2.5, 5 and 10 mg/kg of body weight were tested against the natural infections with Fasciola hepatica, F. gigantica, Dicrocoelium dendriticum, Paramphistomum spp., Ostertagia spp., Nematodirus spp., Bunostomum trigonocephalum, Oesophagostomum venulosum, Chabertia ovina and Trichuris spp. in merino sheep. Results were evaluated according to both egg counts reductions in per gram feces and necropsy findings. Percent reductions of fecal egg counts in Fasciola and gastrointestinal nematode infections were 33.1 % and 98.5 % at the dose of 2.5 mg/kg, and 49.7 % and 99 % at 5 mg/kg, and 98.7 and 100% at 10 mg/kg respectively. At the necropcies, Albendazole at 2.5, 5 and 10 mg/kg were 60.2 %, 71. 8 % and 97.4 % effective against Fasciola spp. respectively. Activity against gastrointestinal nematodes varied between 99.2-100% at the doses of 2.5 and 5 mg/kg. Albendazole was completely (100 %) effective against adult gastrointestinal nematodes at 10 mg/kg. No side effects were observed at any doses administred. Albendazole showed relatively poor activity against D. dendtiticum and Paramphistomid parasites.