1988 Cilt 7 Sayı 1-2-3
Permanent URI for this collectionhttps://hdl.handle.net/11452/31984
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Item Farelerde oluşturulan i̇mmunosuppresi̇f etki̇ ile kanlarındaki vitamin A ve Beta-karoten düzeyleri arasındaki ilişkiler üzeri̇nde bir araştırma(Uludağ Üniversitesi, 1988) Mert, Nihat; Kahraman, Mustafa; Oğan, Canan; Şeker, Ayşin; Veteriner Fakültesi; Mikrobiyoloji Ana Bilim DalıEighty white mice were divided equally into 4 groups. Group I unvaccinated controls, Group II vaccinated controls Group III. experimental group receiving 400 mg/lt. nitriate and Group IV. experimental group receiving 400/lt. intriate in drinking water. All mice except the group I were vaccinated with Newcastle disease virus, Hitchner B1 strain subcutaneously. Three times repeatedly every other day. Serum samples for each group of mice were obtained from the blood pooled of each group were examined for the amount of vitamin A and Beta-caroten and for the immunosuppresive effect of nitrite and nitrate on the mice. All of the three parameters were found to be decreased, in groups of mice receivied nitrite and nitrate canpating the other groups. Amounts of Beta-caroten were measured as 5.236 3.336, 1.428 and 0.952 mgr/100 ml. in groups I, ll, III and IV respectively. Vitamin A values were high in group I and II (46.74) and 47.64) and were 28.38 and 21.98 mg/ml in 100 ml/serum in groups III and IV. HI titres were determined as 2-² , 2-⁶ and 2-⁵ and 2-⁴ indicating lower titers in the experimental groups.Item Hayvan yetiştiriciliğinde antibiyotik kullanımının insan sağlığına etkisi(Uludağ Üniversitesi, 1988) Minbay, Ahmet; Erdinç, Hüseyin; Berker, Aşkın; Veteriner Fakültesi; Hayvan Besleme ve Beslenme Hastalıkları Ana Bilim DalıToday, one of the important problems concerning public health is ensuring a balanced and adequate nutrition of the society. On the one hand, it is necessary to increase the production of food in order to feed the society in a sufficient and balanced way, and on the other hand, it is necessary to ensure that nutrients are delivered to the consumer in healthy conditions. The fact that the foods consumed are reliable in terms of human health is among the most striking news all over the world and in our country. Food control and technology in the modern sense requires the detection of microorganism drug and toxic substance residues, which are likely to be present in foodstuffs, on routine examinations. In this article, the usage purposes of antibiotics used especially in the breeding of livestock and the effect of this use on human health will be emphasized. Antibiotics, as a general definition, are substances that are formed by a microorganism and prevent them from harming animal and human health by killing other microorganisms or preventing their reproduction. Antibiotics give successful results in the treatment of many infectious diseases of animals and humans, which are primarily caused by bacterial factors. In recent years, antibiotics that are successful in the treatment of parasitic, fungal and viral infections have been obtained in addition to bacterial infections. The drugs to be used in the treatment of infectious diseases in humans and animals, directly affecting the disease agent, and not harming the health of the treated person or animal is a feature that is primarily sought. The first successful, specific effective substance in the history of medicine was a synthetic organic compound containing arsenic, which was introduced as the "magic bullet" by Paul Ehrlich at the beginning of the 20th century. Although this compound, which is effective in the treatment of syphilis and other spirochetal infections, is promising, it could not deliver what was desired due to its side effects. In the 1940s, the period of use of antibiotics against many infectious diseases affecting human and animal health began and with this period, the possibility of more effective control and treatment of infectious diseases was born. Discovered by Alexander Fleming in 1929, penicillin was started to be produced for commercial purposes in the 1940s and the first antibiotic that gave successful results in the treatment of various infectious diseases was found. Intense research has been done on antibiotics in the period that has passed until today. As a result of these studies, many new antibiotics have been found and they have found wide application areas in the treatment of bacterial, viral, fungal and parasitic diseases of humans and animals, infectious diseases, prevention and growth accelerators in animals.Item Nitrat ve nitrit'in immunosuppresif olarak etkiledikleri farelerde bazı biyolojik değişiklikler üzerinde araştırmalar II. bazı doku ve organlarda gözlenen histopatolojik değişiklikler(Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Ertürk, Erdoğan; Özkula, Mihriban; Sönmez, Gürsel; Veteriner Fakültesi; Mikrobiyoloji Ana Bilim DalıEighty Swiss mice divided into 4 equal groupı as follow: Group I Negative controls (nonvaccinated with Newcastle Disease vaccine and did not receive any additional treatment); Group. Il was consisted of 20 mice that received ND vaccine only; Group III had 20 mice that were ND vaccinated and drunk nitrite water (0.4 gr/lt) and the last group IV, had equal number of mice that were immunostimulated with ND vaccination and was additionally treated with nitrate in their drinking water (0.4 gr./lt) for a period of 26 weeks. Three mice randomly selected from each group were used to obtain blood samples and histopathological evaluations by the termination. The respective HI tilers for groups were 2-², 2-⁶, 2-⁵ and 2-⁴.The second group (vaccinated controls) being highest and followed by the third and the fourth groups showed moderate severe to lymphoid hyperplasia in thymus, peripheral lymph nodes and payer patches observed by light microscopy. In some cases, as the result of this severe lymphoid response, some mononuclear cell infiltrations into kidney, liver and even into the lungs were detected. The strength of hyperplasia and resulting infiltrations were in agreement with the immunosuppressive potential of nitrate and nitrite administered in drinking water.Item Sterilizasyon(Uludağ Üniversitesi, 1988) Kahraman, Mustafa; Veteriner Fakültesi; Mikrobiyoloji Ana Bilim DalıHerhangi kullanılacak bir maddenin veya yiyeceğin mikropsuz hale getirilmesine STERİLİZASYON denilir. Bunu dezenfeksiyon ile karıştırmamak gerekir. Dezenfeksiyon bulaşık bir maddenin mikroplarını öldürmek için kimyasal vasıtalarla yapılan işlemdir.