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Permanent URI for this collectionhttps://hdl.handle.net/11452/19318

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Diagnosis and management of cow's milk protein allergy in Turkey: Region-specific recommendations by an expert-panel
(Codon Publications, 2019-05-06) Güler, Nermin; Çokugraş, Fügen Çullu; Selimoğlu, Ayse; Türktaş, İpek; Çokuğras, Haluk; Aydoğan, Metin; Beşer, Ömer Faruk; Naik, Sapan; Tıp Fakültesi; Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı; FUI-8766-2022; 6602156485
Cow's milk protein allergy (CMPA) is the most common type of food-allergy in younger Cow's milk protein children. Prognosis is usually good, with most children developing tolerance before school age. allergy; Children may present with a wide spectrum of symptoms that range from mild to severe; skin Consensus report; reactions such as angioedema and urticaria and gastrointestinal symptoms are the most common Turkey presentations of CMPA. Approximately one-third of CMPA patients suffer from multiple food allergies; severe conditions such as anaphylactic shock (9%), eosinophilic esophagitis (4.7%), and food-protein induced enterocolitis (1%) may also develop in some children. Timely and accurate diagnosis and management is essential for proper growth and development of children with CMPA. In this expert consensus report, we aimed to adapt current understandings in the CMPA field to the specific conditions in Turkey and health system to help physicians with their day-to-day decision making.
Kounis syndrome not induced but prevented by the implantation of a drug-eluting stent: A case report
(Aves, 2017-05) Alışır, Mehmet Fethi; Terzioğlu, Kadriye; Ediger, Dane; Öztürk, Raziye Tülümen; Durmuş, Eda; Tıp Fakültesi; Alerji ve İmmünoloji Ana Bilim Dalı; 0000-0002-2954-4293; AAE-9142-2019; 56404619600; 8833423000; 57194142869; 56506969700
Kounis syndrome is an allergy-associated acute coronary syndrome, which develops secondary to mast cell activation in coronary arteries due to hypersensitivity or anaphylactoid reaction (1). The triggering factors may be various drugs, food, environmental exposure, and intracoronary stents (2–4). In this case report, an extraordinary case of Kounis syndrome (acute myocardial infarction with concomitant allergic reaction to paracetamol/propyphenazone) has been presented.
What we learned about COVID-19 so far? Notes from underground
(AVES, 2020-05) Günaydın, Fatma Esra; Tıp Fakültesi; Alerji ve İmmünoloji Ana Bilim Dalı; HKV-2265-2023; 57210113218
The novel coronavirus pandemic poses a major global threat to public health. Our knowledge concerning every aspect of COVID-19 is evolving rapidly, given the increasing data from all over the world. In this narrative review, the Turkish Thoracic Society Early Career Taskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment, prevention, and control of COVID-19. Studies revealed that the genetic sequence of the novel coronavirus showed significant identity to SARS-CoV and MERS-CoV. Angiotensin-converting enzyme 2 receptor is an important target of the SARS-CoV-2 while entering an organism. Smokers were more likely to develop the disease and have a higher risk for ICU admission. The mean incubation period was 6.4 days, whereas asymptomatic transmission was reported up to 25 days after infection. Fever and cough were the most common symptoms, and cardiovascular diseases and hypertension were reported to be the most common comorbidities among patients. Clinical manifestations range from asymptomatic and mild disease to severe acute respiratory distress syndrome. Several patients showed typical symptoms and radiological changes with negative RT-PCR but positive IgG and IgM antibodies. Although radiological findings may vary, bilateral, peripherally distributed, ground-glass opacities were typical of COVID-19. Poor prognosis was associated with older age, higher Sequential Organ Failure Assessment score, and high D-dimer level. Chloroquine was found to be effective in reducing viral replication in vitro. Likewise, protease inhibitors, including lopinavir/ritonavir, favipiravir, and nucleoside analogue remdesivir were proposed to be the potential drug candidates in COVID-19 management. Despite these efforts, we still have much to learn regarding the transmission, treatment, and prevention of COVID-19.

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