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ACTH stimulation test in lean polycystic ovary syndrome patients with insulin resistance
(Elsevier, 2006-12-09) Uncu, Gürkan; Özyürek, S. Eser; Uncu, Yeşim; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-5225-4403; AAT-3479-2021; 6603716169; 57215443453; 8892370600
Objective: To determine whether insulin resistance in nonobese polycystic ovarian syndrome (PCOS) patients is associated with a higher response to ACTH stimulation. Design: Controlled prospective study. Setting: University hospital ambulatory care unit. Patient(S): Twenty nonobese PCOS syndrome patients with insulin resistance and a body mass index-matched control group of 20 nonobese PCOS patients without insulin resistance. Intervention(S): A 75-g oral glucose tolerance test and an ACTH stimulation test. Main Outcome Measure(S): Blood insulin and glucose levels after ingestion of 75 g oral glucose; blood androstenedione (A), 17(OH)-progesterone [17(OH)-P], free and total T, DHEAS, and progesterone (P) response to ACTH stimulation. Result(S): The proportional increases in the blood levels of total and free T, DHEAS, A,17(OH)-P, and P following ACTH stimulation were similar in the two groups. Only the insulin area under the curve (AUC) values were significantly different among the two groups. The insulin AUC values were positively correlated to the free T blood levels and the homeostasis model assessment scores. Conclusion(S): Within the population of nonobese PCOS patients, insulin resistance is not associated with a more pronounced response to ACTH stimulation. The pathogenesis and management of PCOS in nonobese patients may be different from in obese patients.
Attitudes of Turkish men toward wife beating: A study from Bursa, Turkey
(Springer/Plenum Publishers, 2008-10) Özçakır, Alis; Bayram, Nuran; Ergin, Nilüfer; Selimoğlu, Kerem; Bilgel, Nazan; İktisadi ve İdari Bilimler Fakültesi; Ekonometri Bölümü; 0000-0001-5588-2037; 0000-0001-5492-184X; AAG-8209-2021; AAG-9068-2021; 9733230000; 13609585600; 8927016800; 8927016900; 7801564702
The objectives of this cross-sectional, descriptive, questionnaire study were to explore men's attitudes toward wife beating and examine the possible predictors. A total of 1,150 married men aged 18 and up, who had received primary health care in a defined period were the participants. The lifetime prevalence of wife beating was 29.0%. Of the men studied, 42.7% were themselves victims of physical violence during childhood. About 17.9% of the participants thought that they had the right to beat their wives. Significant predictors in logistic regression analysis included women's low education (OR=2.8; 95%CI=1.26-6.46), number of children (OR=2.4; 95%CI=1.34-4.51), childhood beatings (OR=1.6; 95%CI=1.25-2.16) and alcohol intake (OR=1.9; 95%CI=1.49-2.63).Wife beating is a problem in Turkey. To change male attitudes, alcohol abuse control interventions and child abuse prevention should be implemented.
Body fat distribution has no effect on serum visfatin levels in healthy female subjects
(Academic Press - Elsevier Science, 2010-03) Ersoy, Canan; Sadıkoğlu, Ganime; Orhan, Hasan; Güçlü, Metin; Sarandöl, Emre; Akgün, Meral Demirci; Özçakır, Alis; İmamoğlu, Şazi; Tıp Fakültesi; Tıbbi Biyokimya Ana Bilim Dalı; 0000-0002-2593-7196; 0000-0001-5588-2037; ABI-4847-2020; ABE-1716-2020; AAG-8209-2021; AAH-8861-2021; 6701485882; 22956348700; 36126806400; 15073842600; 55943324800; 36125941900; 9733230000; 6602297533
Obesity is the presence of either abnormal absolute amount or relative proportion of body fat. Contrary to gluteal obesity, visceral obesity is associated with different metabolic alterations including insulin resistance (IR). A relatively new adipocytokine visfatin is shown to be expressed predominantly in visceral fat and exhibit insulin-mimicking effects in rodents. It is still unclear whether serum visfatin levels are associated with increased total or visceral fat mass in humans. The aim of our study was to investigate the relation between visfatin and obesity parameters namely body mass index (BMI) and waist circumference (WaC) and IR in healthy female subjects. Eighty one female subjects >= 20 years of age, having no diagnosis of glucose intolerance or diabetes, hypertension and dyslipidemia were chosen. The patients were divided into four groups according to their BMI and WaC values. Serum visfatin and HOMA-IR levels did not differ among groups. No correlation was detected between serum visfatin levels and obesity and metabolic parameters. In conclusion, we demonstrated that body fat distribution did not affect serum visfatin levels in healthy female subjects. Further studies are needed to clarify the exact factors influencing and determining serum visfatin levels and its clinical reflections.
Bullying in Turkish white-collar workers
(Oxford Univ Press, 2006) Bilgel, Nazan; Aytaç, Serpil; Bayram, Nuran; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0001-5492-184X; 0000-0001-6659-4639; 0000-0002-4539-5849; AAG-9068-2021; I-7814-2019; 7801564702; 56835333800; 13609585600
Objectives To determine the prevalence of reported workplace bullying among a group of white-collar workers, to evaluate the association between reported bullying and its effect on health and to assess the effects of support at work for bullied workers. Methods A cross-sectional questionnaire survey among full-time government employees in the health, education and security sectors. Bullying was assessed using a 20-item inventory. The potential effects of reported bullying were assessed using the Job Induced Stress Scale, the Hospital Anxiety and Depression Scale, Job Satisfaction Scale and the Propensity to Leave Scale. Results The response rate was 79% (944/1200) and 877 questionnaires were analysed after exclusion of non-complete data. Of respondents, 55% (483) reported experiencing one or more types of bullying in the previous year and 47% (416) had witnessed the bullying of others. The bully was most likely to be a superior. Sixty per cent of victims had tried to take action against bullying, but most were dissatisfied with the outcome. There were significant differences in anxiety, depression, job-induced stress and support at work scores between those reporting bullying and those not reporting bullying at work. Those who reported bullying with low support at work had the poorest scores on the mental health scales. Conclusions Bullying is a serious problem in this group of workers and may lead to health consequences. Feeling that the work environment is supportive appears to have a protective effect in terms of the health outcomes.
Changes in the management of type 2 diabetic patients in family medicine practices in the Bursa region
(Elsevier, 2017-04) Göktaş, Olgun; Gül, Özen Öz; Ertürk, Erdinç; Tıp Fakültesi; Aile Sağlığı Merkezi; İç Hastalıkları Bölümü; AAJ-6536-2021; AAI-1005-2021; 6603078279; 26040787100; 7005488796
Aim: The aim of the study was to investigate the treatment and monitoring patterns of type 2 diabetes patients in the Bursa region over the last 5 years since the implementation of family practice in Turkey in 2010. Methods: A total of 216 volunteer family doctors working in family health centers took part in this study. The records of 44,819 diabetic patients who visited these doctors between January 1, 2010 and December 31, 2014 were inspected retrospectively. Apart from the identity of the patients, morphometric data, including the type of medication used for diabetes and the HbA1C, serum creatinine and LDL cholesterol values, were recorded. Results: A total of 38.9% (17,416 patients) of the patients in the study were male and 61.1% (27,403 patients) were female. The average age was 59.7 years with a range of 13.2 years. Although the patients' average body mass index (BMI) did not change over the 5 years monitoring, average blood pressure (BP), and serum creatinine and LDL cholesterol levels decreased significantly. The hemoglobin A1c levels were significantly lower after 2010 compared to the 2010 data. Upon examining the medication prescribed for the patients, we determined that the use of metformin and insulin increased, whereas the prescription of thiazolidinedione (glitazone) decreased. There was a significant increase in the amount of patient data recorded over the last 5 years. Conclusions: Despite the increased level of data entry in these patients with type 2 diabetes, the surveillance of diabetes parameters according to treatment guidelines remains suboptimal. There continues to be a need to engage family practitioners on ongoing education and practice enhancement programs.
Characteristics of Turkish marital properties of Turkish outpatient population
(Drunpp-Sarajevo, 2012) Mergen, Berna Erdoğmuş; Dağlı, Zehra; Uncu, Yeşim; Mergen, Haluk; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-5225-4403; 0000-0002-5225-4403; AAP-9210-2020; A-1204-2018; D-9597-2016; 8892370600; 27467601400
Objective: To dispose the marital properties, problems and resolution ways among Turkish people based on our trial. Materials & methods: This was a population-based, cross-sectional study. Four hundred and ninety two people addressing to three different health centers have been contributed to study by a written informed consent during September, 2004 and November, 2004. Subjects completed a questionnaire assessing their marriages. Results analyzed in SPSS 11.0. T-test, covariance, linear regression and descriptive statistics used. Results: Of subjects, 88 % were women and 12 % men. Mean age was 42.5 +/- 10.34(SD). Wedding age and marriage duration found higher in men than women. Youth prefers flirting more than elder people do. Violence found in 13.5 % of subjects: all women. Divorce thought by 22.6 % of the subjects in any time of marriage. Conclusion: Turkish couples have different marital properties compared to other nations because of strictness to religion, morale and traditions.
Clinical characteristics of essential and physiological tremor in Orhangazi district of Bursa, Turkey: A population based study
(Journal Neurological Sciences, 2009) Erer, Sevda; Zarifoğlu, Mehmet; Karlı, Necdet; Özçakır, Alis; Çavdar, Çiğdem; Ocakoğlu, Gökhan; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0001-5588-2037; AAH-5180-2021; AAG-8209-2021; 25635370800; 6603411305; 6506587942; 9733230000; 25935825700; 15832295800
To find out the estimated prevalence and clinical features of tremor and its subtypes, such as essential tremor (ET) or physiological tremor (PT), by means of a population-based study in the Orhangazi district of Bursa, Turkey. Our study was carried out between June 2004 and September 2005 among adults aged 40 years or more in Orhangazi, Bursa, Turkey. This population-based study was planned in 3 phases. In phase 1, face-to-face home interviews with 1124 subjects were carried out by residents of the departments of neurology and family medicine, using a short questionnaire; 247 persons had symptoms indicative of tremor. Of the persons with tremor symptoms in phase 1, 48 did not continue to phase 2. In phase 2, participants were videotaped and evaluated by movement disorders specialists by using scales specific to tremor. In phase 3, video recordings of all identified patients were reviewed and final diagnoses were made through a consensus of all three specialists. In the study population, the prevalence rate of ET was found to be 3.34%; of PT, 4.14%; and all types of tremor, 9.00%. There was no significant variability according to gender and age groups in prevalence rate of ET, PT. ET and PT showed significant comorbidity with hypertension (HT), rheumatological disease, diabetes mellitus (DM), and asthma.
Consanguineous marriages in a suburb of a Metropolitan City: A study from Bursa, Turkey
(Ortadoğu Yayınları, 2009-10) Özdemir, Hakan; Alper, Züleyha; Bilgel, Nazan; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-8349-9868; AAB-1694-2021; ABE-2261-2020; 57197077578; 8580079400; 7801564702
Objective: The objective of this study was to explore consanguinity, consanguineous marriages, their different types, and socio-demographic correlates in a suburb of Bursa, the fourth largest city in Turkey. Material and Methods: A total of 1380 ever married women, who attended the Emek Family Medicine Clinic in this suburb over a period of one year, were requested to participate in the study. Those who gave their informed consent were accepted as study participants. A total of I 110 women were interviewed. The questionnaire provided information on consanguinity and socio-demographic data. Analyses were made by using SPSS V.11.5. Results: The mean age of our study participants was (mean SE) 34.2 +/- 0.6 years. Most of them were illiterate and housewives. About one-third of the participants had consanguineous marriages and about 93% of those marriages were between first cousins. Among first cousin unions, marriage with uncle's male child was the most common. The mean coefficient of inbreeding was 0.015458. Consanguineous marriages were more prevalent among illiterate women, Consanguineous marriages were 4 times more common in women with a family history of consanguinity than in women without any such history. There were no significant correlations between consanguineous marriages and reported stillbirths, miscarriages or infant deaths. However, we found a significant relationship between consanguineous marriages and reported congenital malformations of the offspring. Conclusion: We conclude that offspring of consanguineous unions are at high risk for some congenital malformations and diseases. Hence, we recommend that families with a high risk for genetic diseases be identified and be provided with prospective genetic counseling.
Counterproductive work behavior among white-collar employees: A study from Turkey
(Wiley, 2009-06) Bayram, Nuran; Gürsakal, Necmi; Bilgel, Nazan Gönül; İktisadi ve İdari Bilimler Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0001-5492-184X; 0000-0002-4539-5849; AAG-9068-2021; 13609585600; 26429334100; 7801564702
The current study was designed to evaluate the magnitude and types of counterproductive work behaviors (CWBs) among a group of white-collar employees from different firms. A total of 766 employees voluntarily participated in our study. We focused especially on employees' perceptions of their work environment and on their affective responses to those perceptions. Data were dependent on self-reporting and privacy, and anonymity measures were taken into account. The five different instruments used to evaluate job satisfaction were, organizational constraints, interpersonal conflict, quantitative workload and CWB. We found a high degree of job satisfaction, a minimal quantitative workload and a limited exhibition of CWBs among our sample. Organizational constraints were found to be the most strongly correlated to exhibited CWBs, followed by interpersonal conflict and quantitative workload. Job satisfaction had a diminishing effect on CWBs. Among the five dimensions of CWBs, abuse and withdrawal were found to be the most important. The most frequently reported CWB was 'came to work late without permission.' Except for income we found no statistically significant relationship between demographic characteristics and the exhibition of CWBs. We concluded that by abolishing pre-existing organizational constraints there may be a reduction in CWBs.
Does the anatomical localization of lower extremity venous diseases affect the quality of life?
(Saudi Med J, 2006) Sadıkoğlu, Ganime; Özçakır, Aliş; Ercan, İlker; Yıldız, Caner; Sadıkoğlu, Yurtkuran; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0001-5588-2037; 0000-0002-2382-290X; AAG-8209-2021; 22956348700; 9733230000; 6603789069; 23500430800; 6602402845
Objective: To investigate the effects of venous diseases at different anatomical localizations on the qualities of life of patients with varicose veins. Methods: The study included 354 cases, which was referred to a private vascular and interventional radiology center in Bursa, Turkey between January 2005 to January 2006. The cases were diagnosed with visual inspection and were clinically indicative of varicose veins. Color Doppler ultrasonography was used to radiologically examine the varicose veins. All cases were accepted as class 11 criteria according to the Clinical, Etiologic, Anatomic, Pathophysiologic classification. The generic Short Form Health Survey-36 (SF-36) was used to measure physical and mental quality of life (QOL). High scores indicated good QOL. The Statistical Package for Social Sciences version 13.0 program was used for the statistical evaluation. Results: When the life SF-36 quality parameters of cases with different anatomical localizations of the varicose veins were examined, only the mental health scores were found to differ in different groups (p < 0.01). In females and males with superficial venous disease, significant differences were found in physical function, physical role and pain among the physical health scale components, and in vitality and emotional role scores among the mental state detem-finants. When females and males with deep vein disease were compared, significant differences were found among both physical and mental health determinants. Conclusions: Anatomical localization of lower extremity varicose veins can be accepted as a predictive factor in determining the life qualities of patients with varicosities in their lower limb, and should be used to regulate their therapy and follow up protocols.
Domestic violence: A tragedy behind the doors
(Routledge Journals, 2005) Ergin, Nina; Nuran, Bayram; Alper, Züleyha; Selimoğlu, Kerem; Bilgel, Nazan; İktisadi ve İdari Bilimler Fakültesi; Ekonometri Bölümü; 0000-0001-5492-184X; 0000-0002-8349-9868; 0000-0002-4539-5849; ABE-2261-2020; AAG-9068-2021; AAB-1694-2021; 8927016800; 13609585600; 8580079400; 8927016900; 7801564702
Objective: To explore the prevalence, type, frequency and causes of domestic marital violence among Turkish women in a socio-economically developed metropolitan setting. Methods: A cross-sectional Study was performed in 2003. All married women, aged 18 years and over, who were visiting any of the 50 primary health care units for different purposes were asked to participate in the study. Of 1427 asked, 1010 gave consent and completed face-to-face interviews. Multiple correspondence analysis, and logistic regression were used for statistical analyses. Results: Domestic violence was statistically significantly associated with educational level. Illiterate women reported marital abuse 2.6 times more than university or more educated women. No statistically significant relationship was observed between domestic marital violence and women's age or occupation, marital duration or family income. The most frequently reported type of violence was physical, followed by psychological. Among women reporting domestic violence, those with the lowest educational level and income were experiencing all types of domestic violence frequently. Conclusion: Placing more importance oil educating girls Could be a key component ofprcventing domestic violence.
Educating medical students about the personal meaning of terminal illness using the film, "wit"
(Mary Ann Liebert, 2014-08) Özçakır, Alis; Bilgel, Nazan Gönül; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-8209-2021; 9733230000; 7801564702
Background: Addressing the emotional needs of dying patients is rarely found to have a place in formal medical curriculum and is also a difficult area to teach through classical medical lectures. "Cinemeducation" is a wonderful way to educate health care providers about the magnitude of emotions that arise during those difficult situations. Objective: The aims of this study were to test the relevance and usefulness of the movie 'Wit' in teaching medical students about the personal meaning of terminal illness and to assess the impact of this teaching method on students' attitudes toward palliative care. Design: This was an education study using qualitative and quantitative data analysis of 518 first-year medical students in a single medical faculty in Turkey. Students watched the entire film, filled out an evaluation questionnaire, and answered questions about the film. Students also expressed their own feelings and thoughts about palliative care. Results: Overall, 88% rated the film as excellent, very good, or good. According to 54% of the students, the emotions of terminally ill patients were fully portrayed in the film and in a very realistic way. Approximately 61.4% of the students found this film emotional. Most students (80.5%) stated that this film made them think about the emotional and spiritual suffering that dying patients go through and found this learning approach about palliative care more useful than didactic lectures and journal article readings but not more useful than bedside rounds. It was thought that caring for dying patients would be very or fairly personally satisfying for 65.3% of the students. Conclusions: The film 'Wit' gave the students an opportunity to explore their beliefs, values and attitudes in terms of the bio-psycho-social-spiritual aspects of health care and encouraged them to think more about the humanitarian issues of the medical profession.
The effects of different hormone replacement therapy regimens on tear function, intraocular pressure and lens opacity
(Taylor & Francis, 2006) Uncu, Gürkan; Avcı, Remzi; Uncu, Yeşim; Kaymaz, Cafer; Develioğlu, Osman; Tıp Fakültesi; Göz Hastalıkları Ana Bilim Dalı; 0000-0002-5225-4403; 0000-0002-5225-4403; AAP-9210-2020; D-9597-2016; AAT-3479-2021
Objective. Estrogen may have adverse effects on the ocular surface, intraocular pressure (IOP), lens opacity and tear function. The aim of the present study was to elucidate the effects of different hormone replacement therapy (HRT) protocols on tear function, IOP and lens opacity. Design and setting. This was a prospective, uncontrolled study carried out at the Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Faculty of Medicine, Uludag University, Turkey. Patients and interventions. Thirty postmenopausal patients who had spontaneous or surgical menopause for at least 1 year and were not taking any medications were assigned to one of three groups. Group 1 comprised 19 patients (n = 38 observations) given conjugated equine estrogen 0.625 mg plus medroxyprogesterone acetate 2.5 mg (Premelle 2.5((R))) daily; Group 2 contained six patients (n = 12 observations) given tibolone 2.5 mg (Livial((R))) daily; and Group 3 comprised five patients (n = 10 observations) treated with estradiol patch, 3.9 mg/12 cm(2) (Climara((R))). Tear function, evaluated with Schirmer's test, IOP and lens opacity were determined before treatment and at 6 and 12 months of treatment. Results. Mean Schirmer's test score in each group and all eyes (n = 60) did not change significantly after 6 months of treatment but decreased significantly at 12 months. The percentage decrease in tear function was greatest in the estrogenonly group (Group 3). Mean IOP did not change significantly in Groups 1 and 2; however, in Group 3, IOP showed a statistically significant decrease from 14.63 +/- 0.84 mmHg before treatment to 12.60 +/- 0.68 mmHg (mean standard error) at the end of treatment. Lens opacity in women of all groups did not change during treatment. Conclusions. HRT decreased tear production, the decrease being greater in the estrogen- only group. Woman who are taking or considering HRT should be informed of the potential increased risk of dry eye syndrome with this therapy. In addition, estrogen-only treatment decreased IOP while estrogen plus progesterone and tibolone had no effect. HRT did not affect lens opacity after 12 months of treatment.
Factors associated with depression among Turkish faculty of education freshmen by Beck depression Inventory-II-Turkish
(Slovene Medical, 2009-10) Öngel, Kurtuluş; Mergen, Haluk; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; A-1204-2018; 27467601400
Aims: To assess the prevalence of depression among the first-year university students. Methods: 237 freshmen contributed anonymously to the study on a voluntary basis and an informed consent was obtained. Beck Depression Inventory-II Turkish (BDI-II-T) was applied. SPSS 11.0 statistical program was used. Results: Overall depression prevalence was 8.4%. 54.9% of subjects were females. 3 factors were found: factor 1 (depressive) with 11.2%, factor 2 (cognitive) with 9.7% and factor 3 (somatic-affective) with 8.8% of total variance. Mild depression was found in 5.9%, moderate in 1.7% and severe depression in o.8% of subjects. Conclusion: BDI-II-T was found to be useful for the detection of depression among freshmen in terms of academic failure and future health.
Health literacy among adults: A study from Turkey
(Oxford Univ Press, 2010-06) Özdemir, Hakan; Alper, Züleyha; Uncu, Yeşim; Bilgel, Nazan Gönül; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-8349-9868; 0000-0002-5225-4403; 0000-0002-4539-5849; ABE-2261-2020; D-9597-2016; 57197077578; 8580079400; 8892370600; 7801564702
Patients' health literacy is increasingly recognized as a critical factor affecting health communication and outcomes. We performed this study to assess the levels of health literacy by using Rapid Estimate of Adult Literacy in Medicine (REALM) and Newest Vital Sign (NVS) instruments. Patients (n = 456) at a family medicine clinic completed in-person interviews, REALM and NVS tests which were translated into the Turkish language by translation-back translation process. Additional questions regarding demographic characteristics were also collected. The mean scores (mean +/- standard error) for REALM and NVS were 60.2 +/- 90.32 and 2.60 +/- 0.08, respectively. The REALM test scores showed that 2.7% had inadequate (less than or equal to 6th grade), 38.6% marginal (7th to 8th grade) and 58.7% (greater than or equal to 9th grade) adequate health literacy. The NVS test score revealed a proportion of 28.1% had adequate health literacy. Educational attainment was the most important demographic characteristic found to be related to the health literacy. Reading and vocabulary skills were better than numerical capabilities. Female, primary school educated and poor economic condition participants and those who were older had the lowest scores in both the tests.
How parental attitudes affect the risky computer and internet usage patterns of adolescents: A population-based study in the Bursa district of Turkey
(Natl Inst Public Health, 2014-12) Büyükuysal, Çaǧatay; Kılıç, Emine Zinnur; Uncu, Yeşim; Vural, Pınar; Alper, Züleyha; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-5225-4403; 0000-0002-8349-9868; AAP-9210-2020; AAB-1694-2021; 8892370600; 24437388700; 8580079400
Background: We aimed to evaluate the computer usage patterns of adolescents and to determine the effects of family life and parental attitude on these patterns. Methods: This was a descriptive, cross-sectional, population-based survey that included 935 children between 11 and 16 years of age who were students in the second level of primary school and their parents as well. The following instruments were used in the survey: student and parent questionnaires on computer usage patterns and the Parental Attitude Research Instrument (PARI) to assess parental attitudes towards. child-rearing and family life. Results: Of the study population, the majority of the students had a computer in their homes and spent a lot of time on the Internet. Parental control over the amount of time spent on the Internet and the websites that were visited had sometimes limited and contradictory effects on computer usage among the students. A democratic parental attitude was the best approach. Using the computer as a reward or punishment had a negative impact on the children's computer usage patterns. Conclusions: Although parents are confused concerning the benefits and harms of the Internet for their children and not certain how to manage their children's use of the computer and safe navigation of the Internet, a democratic parental attitude appears to be the best approach for reaching the most beneficial computer usage patterns for students.
Importance of novel sequence alterations in the FHIT gene on formation of breast cancer
(Sage Publications, 2007-03-07) Bilgel, Nazan; Tolunay, Şahsine; Taşdelen, İsmet; Tunca, Berrin; Egeli, U.; Çeçener, Gülşah; Tıp Fakültesi; Patoloji Ana Bilim Dalı; 0000-0002-1619-6680; 0000-0002-3820-424X; 0000-0001-7904-883X; 0000-0002-4539-5849; 6508156530; 55665145000; 6602965754; 9637821500; 6602604390; 7801564702
Aims and background: The character, role and impact of FHIT gene alterations, for which recent studies have shown that the gene has a role in the early stage of carcinogenesis in breast cancer, are still unclear. Thus, the current study evaluated FHIT gene mutations from breast tissue of women with malignant and benign breast disease and to elucidate the frequency and type of mutations in this gene. Patients and methods: Mutations in exons 5-9 of the FHIT gene were screened using the intronic primer pairs in 83 breast (67 malignant and 16 benign) tissue samples by single-strand conformational polymorphism and sequencing analysis. Results: FHIT mutations were detected in 13 of the 67 malignant cases (19.4%) and 2 of the 16 benign cases (12.5%). Four different sequence variants were determined: two novel frame shift mutations (codon 90 insA, codon 146 deIT), one intronic novel mutation (IVS8 -17 insA), and one previously identified silent transition type alteration (codon 88 C to T). In addition, determination of this silent alteration caused formation of new exonic splicing enhancer (ESE) motifs on mutated sequences by using the ESEfinder program. Conclusions: Our data contribute significantly to that currently known about the presence of FHIT gene mutations on the formation of breast cancer.
Investigating the scientific process skills of medical students in relation to medical decision making: Research on basic medical science competence
(Slovene Medical, 2009-11) Öngel, Kurtuluş; Katrıcı, Ebru; Ak, Cennet; Sarıkan, İsmail; Özkan, Şule; Cesur, Gökhan; Erdal, Sevinç Öngel; Mergen, Haluk; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; A-1204-2018; 27467601400
Background: Medical students are expected to convey scientific literacy and possess certain scientific skills prior to being admitted to medical schools. Laboratory practices being provided during their education play a crucial role in their professional development and the usefulness of these practices is possible and can be enriched if the students possess prior scientific skills. The purpose of this study is to determine the scientific process skills of second year medical students in Suleyman Demirel University, Faculty of Medicine, Turkey. Methods: The study was conducted in April 2006 by using the Scientific Process Skills Questionnaire (SPSQ) for laboratory practices. Randomly selected (n = 76) second year medical students participated in the study. Results: Nine basic scientific process skills were investigated. All of the students responded correctly to the question that measured their ability to interpret data. Students abilities to set up hypothesis and make estimations were found quite high. (94.7 %, 92.1 % respectively) The two skills that were challenging to students were the ability to make an observation and their proficiency in scales. The percentage of correct responses to those questions were 50 % and 50.5 % respectively. Conclusions: The study suggests that students in the study group possess the necessary scientific process skills at some degree (86 %). However, this ratio, thus the productivity of laboratory practices can be enhanced by building up on skills such as making observations and interpreting scales. Quality in medical education cannot be achieved if we do not provide our students with basic scientific process skills early in their education.
Job related affective well-being among primary health care physicians
(Oxford University, 2007-10) Yeşim, Uncu; Bayram, Nuran; Bilgel, Nazan; İktisadi ve İdari Bilimler Fakültesi; Ekonometri Bölümü; 0000-0001-5492-184X; 0000-0002-5225-4403; 0000-0002-4539-5849; D-9597-2016; AAG-9068-2021; 8892370600; 13609585600; 7801564702
Background: Job related affective well-being is important for a healthy life and job satisfaction for all individuals, including physicians. The later group, however, is most often compromised. Objectives: We aimed to investigate a group of Turkish primary health care physicians' job related emotional perceptions and to assess their reactions in terms of stress, anxiety and depression. Methods: A descriptive, cross-sectional, self-reported questionnaire study was conducted. A total of 60 primary health care centres and 274 general practitioners who were working at these centres participated in the study. The response rate was 74%. Printed questionnaires were completed by the participants anonymously. We used the Job Related Affective Well-Being Scale (JAWS) and Depression Anxiety Stress Scale (DASS 42). Correlation analysis and hierarchic regression were performed. Results: Correlations between JAWS and DASS total scores were negative and statistically significant (r = -0.52; P< 0.01). Low pleasure/high arousal (LPHA) and low pleasure/low arousal (LPLA) variations that describe negative emotional states show a positive and significant relationship with depression, anxiety and stress values. The highest mean score was obtained for the high pleasure/low arousal (HPLA) status that can be interpreted to mean that our study group was pleased with their job but was not motivated. Conclusions: Physician's job related negative emotional perceptions are associated with reactions in terms of stress, anxiety and depression. For this reason, it is critical to consider primary care physicians' job related affectations and job related stimuli.
The knowledge and attitudes about mammography in a group of Turkish women who attended a family medicine clinic
(Wiley, 2008) Sadıkoğlu, Ganime; Özçakır, Alis; Bayram, Nuran; Bilgel, Nazan Gönül; Tıp Fakültesi; İktisadi ve İdari Bilimler Fakültesi; Aile Hekimliği Ana Bilim Dalı; Ekonometri Bölümü; 0000-0001-5492-184X; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-9068-2021; AAG-8209-2021; 22956348700; 9733230000; 13609585600; 7801564702

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