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Browsing by Department "Acil Servis Ana Bilim Dalı"

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    Acute arsenic self-poisoning for suicidal purpose in a dentist: A case report
    (Sage Publications, 2009-01) Yılmaz, Yusuf; Armağan, Erol; Ölmez, Ömer Fatih; Esen, Mehmet; Alkış, Nihan; Dolar, Mahmut Enver; Tıp Fakültesi; Tıp Fakültesi; İç Hastalıkları Ana Bilim Dalı; İç Hastalıkları Ana Bilim Dalı; Acil Servis Ana Bilim Dalı; Gastroenteroloji Ana Bilim Dalı; 0000-0003-4518-5283; AAH-8846-2021; K-6651-2012; AAG-9177-2021; 22936014300; 6506464232; 26435400000; 56567890200; 26533912000; 6602075084
    Arsenic is a classical poison that has been historically used since ancient times for homicidal purposes. More recently, episodes of deliberate or unintentional arsenic self-poisoning have been increasingly reported. We describe here a case of a 77-year old male patient with a history of major depression, who attempted suicide by ingestion of 4 g of arsenic trioxide. The man, a dentist by profession, used arsenic preparations for pulp devitalization. The patient was admitted to our hospital 5 h after arsenic ingestion with nausea and vomiting. Plain radiograph of the abdomen showed radio-opaque material in the stomach and small intestine. Nasogastric lavage, activated charcoal, and chelators; were used to remove arsenic. On day 3, endoscopy disclosed the presence of gastritis and superficial ulcers. The patient developed significant anemia (Hb: 8.7 g/dL on day 7) without significant signs of hemolysis. He gradually recovered from anemia within 5 months. The patient did not suffer any adverse outcome in spite of having ingesting 4 g of arsenic, approximately 20 times the lethal dose.
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    Publication
    The role of Neutrophil Gelatinase-Associated Lipocalin in identifying contrast induced nephropathy development in the emergency department
    (Pakistan Medical Assoc, 2014-10) Pozam, Suna; Özkan, Meral Leman; Aydın Akköse, Şule; Özdemir, Fatma; Köksal, Özlem; Tıp Fakültesi; Acil Servis Ana Bilim Dalı; 0000-0003-2271-5659; AAK-8332-2020; AAI-2164-2021
    Objective: To evaluate the diagnostic significance of neutrophil gelatinase-associated lipocalin in detecting the development of contrast-induced nephropathy in patients undergoing contrast imaging in an emergency. department setting. Methods: The case-control study was conducted at the emergency department of Uludag University, Turkey, between January 1 and July 1, 2012, and comprised patients who underwent a diagnostic thoracic or abdominal Computed Tomography examination with contrast agent. At 2 hours and 72 hours after the scan, control urea, creatinine, and neutrophil gelatinase-associated lipocalin values were recorded. Plasma lipocalin measurement was performed using fluorescence-detected immunoassay method. An increase in serum creatinine of more than 0.5 mg/dl or 25% elevation from the basal level was considered to be a marker for the occurrence of contrast-induced nephropathy. SPSS 13 was used for statistical analysis. Results: Of the 80 subjects in the study, 60(75%) were cases and 20(25%) were controls. Contrast-induced nephropathy did not develop in any of the patients, and, accordingly, no significant increase of plasma urea, creatinine, or neutrophil gelatinase-associated lipocalin levels was observed. A significant positive relationship was found between urea and creatinine levels at 2 hours (p<0.009) and at 72 hours (p<0.001). Conclusions: Diagnostic contrast computed tomography examination in patients with normal renal function did not lead to Contrast-induced nephropathy or increased neutrophil gelatinase-associated lipocalin levels, an accepted early indicator of kidney injury.