1988 Cilt 7 Sayı 1-2-3

Permanent URI for this collectionhttps://hdl.handle.net/11452/31984

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    Farelerde oluşturulan i̇mmunosuppresi̇f etki̇ ile kanlarındaki vitamin A ve Beta-karoten düzeyleri arasındaki ilişkiler üzeri̇nde bir araştırma
    (Uludağ Üniversitesi, 1988) Mert, Nihat; Kahraman, Mustafa; Oğan, Canan; Şeker, Ayşin; Uludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.
    Eighty white mice were divided equally into 4 groups. Group I unvaccinated controls, Group II vaccinated controls Group III. experimental group receiving 400 mg/lt. nitriate and Group IV. experimental group receiving 400/lt. intriate in drinking water. All mice except the group I were vaccinated with Newcastle disease virus, Hitchner B1 strain subcutaneously. Three times repeatedly every other day. Serum samples for each group of mice were obtained from the blood pooled of each group were examined for the amount of vitamin A and Beta-caroten and for the immunosuppresive effect of nitrite and nitrate on the mice. All of the three parameters were found to be decreased, in groups of mice receivied nitrite and nitrate canpating the other groups. Amounts of Beta-caroten were measured as 5.236 3.336, 1.428 and 0.952 mgr/100 ml. in groups I, ll, III and IV respectively. Vitamin A values were high in group I and II (46.74) and 47.64) and were 28.38 and 21.98 mg/ml in 100 ml/serum in groups III and IV. HI titres were determined as 2-² , 2-⁶ and 2-⁵ and 2-⁴ indicating lower titers in the experimental groups.