Browsing by Author "Kasap, Sevim C."
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Item Effects of inulin supplementation on selected faecal characteristics and health of neonatal Saanen kids sucking milk from their dams(Elsevier, 2012-12) Kara, Çağdaş; Orman, Abdülkadir; Gençoğlu, Hıdır; Kovanlıkaya, Arda; Meral, Yavuz; Çetin, İrene; Yibar, Artun; Kasap, Sevim C.; Türkmen, İbrahim İsmet; Deniz, Gülay; Uludağ Üniversitesi/Veteriner Fakültesi/Hayvan Besleme ve Beslenme Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Zooteknik Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Gıda Hijyeni ve Teknolojisi Bölümü.; Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı.; 0000-0002-9217-3034; 0000-0001-9138-4422; AAC-2909-2020; AAP-7998-2020; AAG-9134-2021; K-6112-2016; 31967678500; 24335834100; 15753357900; 31967682500; 55786609400; 7006082971; 38762296900; 36514844800; 6701855392; 8849978100Fifty newborn Saanen kids were used to study the effects of inulin supplementation on faecal score, faecal pH, selected faecal bacterial population, BW, body temperature, haematological traits, selected health parameters and the incidence of diarrhoea. Kids were sorted by parity of their dams and multiple birth (twin or triplet) and assigned to one of the two groups (control: CG, and experimental: EG) at birth. Each group consisted of 25 kids. The groups were similar with regard to sex and birth weight. All kids were fed colostrum for the first 3 days after birth, and then the kids in EG were adapted to inulin supplementation by an increased dosage from day 4 to 7. Each kid in EG was supplemented with 0.2 g, 0.3 g, 0.4 g, 0.5 g and 0.6 g inulin on day 4, 5, 6, 7 and from day 8 to 28, respectively, whereas the kids in CG did not receive inulin. Faecal score and faecal bacterial population were not affected by inulin supplementation (P > 0.05). There were differences in faecal pH on day 14 (P = 0.01) and 28 (P < 0.05), whereas no difference in faecal pH on day 21 (P > 0.05) was detected between groups. No differences (P > 0.05) in BW and haematological traits were found between groups. Body temperature did not differ on day 14 and 21 (P > 0.05), whereas there was a difference in body temperature on day 28 (P = 0.01) between groups. The numbers of kids with pneumonia and kids treated for pneumonia and diarrhoea were similar for CG and EG. Kid losses during the study were the same for CG and EG. The incidence of diarrhoea was not affected by inulin supplementation (P > 0.05). Inulin supplemented to kids did not adversely affect faecal score. The effect of inulin on faecal pH was not consistent. The results of our study suggested that daily dose (0.6 g) of inulin might not be enough to observe effects of it. Our data will be useful to determine the dose and timing of inulin supplementation in future studies investigating the effects of inulin on the parameters associated with performance and health status in kids and other young ruminants.Item Effects of levamisole and ranitidine on antibody-forming responses induced by killed Mycoplasma vaccine antigens in Saanen goats(Wiley, 2012-12-08) Temizel, Ethem Mutlu; Önat, Kaan; Meci̇toğlu, Zafer; Kasap, Sevim C.; Göçmen, Hüban; Ülgen, Mihriban; Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.; 0000-0002-6307-5179; 0000-0002-5557-121X; 0000-0002-2245-5781; AAG-8117-2021; AAP-7998-2020; AAH-1677-2021; B-9095-2018; 26430270100; 24069071700; 36457647300; 36514844800; 56414715500; 56259664500Item Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration(Elsevier, 2019-07-09) Eralp İnan, Oya; Tvarijonaviciute, Asta; Rubio, Camila Peres; Cerón, José Joaquín; Ulus, Ismail Hakki; Kocatürk, Meriç; Kasap, Sevim C.; Cansev, Mehmet; Yılmaz, Zeki; Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Farmakoloji Anabilim Dalı.; 0000-0002-2849-1222; 0000-0001-9836-0749; V-5578-2017; AAP-7998-2020; M-9071-2019; A-9637-2008; 36437200800; 36514844800; 8872816100; 35944810500Endotoxemia treatment options are still of interest due to high mortality and choline treatment is one of them because of its role in the cholinergic anti-inflammatory pathway. This study investigated serum choline and butyrylcholinesterase (BChE) responses, and their correlations with inflammatory, oxidative stress and tissue damage biomarkers, including paraoxanase-1 (PON1), and clinical signs in calves with endotoxemia and the effect of choline treatment in these responses. Healthy calves (n = 20) were divided equally into 4 groups: Control (0.9% NaCl, iv), Choline (C; 1 mg/kg/iv,once), Lipopolysaccharide (LPS; 2 mu g/kg/iv,once) and LPS + C. Clinical and laboratory examinations were performed before and 0.5-48 h (hrs) after treatments. Following LPS administration, serum choline level increased at 0.5-24 h (P < .01), whereas serum BChE and PON1 level decreased at 48 h (P < .01) compared to their baselines. In LPS + C group, the increase in serum choline level was significantly higher (P < .01) than that of C and LPS groups. LPS did not decrease serum BChE levels significantly in calves treated with choline. Serum choline and BChE results correlated negatively with white blood cell count and positively (P < .001) with PON1 levels, oxidative stress index, inflammation and hepato-muscular injury markers. In conclusion serum choline and BChE may have a role in the pathophysiology of endotoxemia in calves. High serum choline concentration is associated with an improvement in response to LPS administration in calves treated with choline, probably by preventing the imbalances between oxidative stress and anti-oxidant capacity, preventing the serum BChE and PON1 decreases, and inhibition/attenuation of acute phase reaction and hepato-muscular injury in calves with endotoxemia.Item A study of Neospora caninum antibody seroprevalence in dairy cows in Turkey(Hellenic Veterinary Medical Society, 2020) Kasap, Sevim C.; Ertunç, S.; Temizel, Ethem Mutlu; Şentürk, Sezgin; Uludağ Üniversitesi/Veterinerlik Fakültesi/Dahiliye Anabilim Dalı; https://orcid.org/0000-0002-2465-9913; AAH-5069-2021; AAP-7998-2020; 36514844800; 57216897883; 26430270100; 56257771200Neospora caninum is a intracellular protozoan parasite and is one of the major causes of repeated abortions, foetal malformations, pre-term deliveries, stillbirth and possible loss of milk yield in livestock. The presence of specific antibodies against N. caninum in the blood serum of dairy cows is investigated in the present study. A total of 184 blood serum samples of dairy cows were examined in Bursa province in the Marmara Region. N. caninum antibodies were measured using an indirect enzyme-linked immunosorbent assay (ELISA) (The Svanovir Neospora-Ab ELISA). From the total sample, antibodies to N. caninum were detected in 62 of the 184 examined cows (33.3%) and neurological findings were seen in a calf.