Browsing by Author "Bodur, Hatice"
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Item Description of the registry of patients with ankylosing spondylitis in Turkey: TRASD-IP(Springer Heidelberg, 2012-01) Bodur, Hatice; Ataman, Şebnem; Buğdaycı, Derya Soy; Rezvani, Aylin; Nas, Kemal; Uzunca, Kaan; Emlakçıoğlu, Emel; Karatepe, Altınay Göksel; Durmuş, Bekir; Sezgin, Melek; Ayhan, Figen; Yazgan, Pelin; Duruöz, Tuncay; Yener, Mahmut; Gürğan, Alev; Kırnap, Mehmet; Çakar, Engin; Soydemir, Raikan; Çapkın, Erhan; Tekeoğlu, İbrahim; Aydın, Gülümser; Günendi, Zafer; Nacır, Barış; Şallı, Ali; Öztürk, Cihat; Memiş, Asuman; Turan, Yasemin; Kozanoğlu, Erkan; Sivrioğlu, Konçuy; Altan, Lale; Uludağ Üniversitesi/Tıp Fakültesi.; AAH-1652-2021; 6603281363A web-based application patient follow-up program was developed to create a registry of patients with ankylosing spondylitis (AS) by the Turkiye Romatizma Arastirma Savas Dernegi (TRASD) AS Study Group. This study describes the methodological background and patient characteristics. The patient follow-up program is a web-based questionnaire, which contains sections on socio-demographic data, anamnesis, personal and family history, systemic and musculoskeletal examination, laboratory and imaging data and treatment. Between October 1, 2007 and February 28, 2009, 1,381 patients from 41 centers were included in the registry (1,038 males [75.2%]; mean age 39.5 +/- A 10.7 years). Mean disease duration was 12.1 +/- A 8.5 years, and mean time from initial symptom to diagnosis was 5 +/- A 6.8 years (median 2 years). HLA-B27 positivity was detected in 73.7% of 262 patients tested. Manifestations of extraarticular involvement were anterior uveitis (13.2%), psoriasis and other skin and mucous membrane lesions (6%) and inflammatory bowel disease (3.8%). The prevalence of peripheral arthritis was 11.2%. In 51.7% of patients, the Bath AS Disease Activity Index was a parts per thousand yen4. But since our patients consisted of the ones with more severe disease who referred to the tertiary centers and needed a regular follow-up, they may not represent the general AS population. Disease-modifying anti-rheumatic drugs were being used by 41.9% of patients, with 16.4% using anti-TNF agents. TRASD-IP (Izlem Programi: Follow-up program) is the first AS registry in Turkey. Such databases are very useful and provide a basis for data collection from large numbers of subjects. TRASD-IP gives information on the clinical and demographic profiles of patients, and the efficacy and safety of anti-TNF drugs, examines the impact on quality of life, and provides real-life data that may be used in cost-effectiveness analyses.Item Polypharmacy in the elderly: A multicenter study(Elsevier, 2009-09) Kutsal, Yeşim Gökçe; Barak, Anıl; Atalay, Ayçe; Baydar, Terken; Tuncer, Tiraje; Hizmetli, Sami; Dursun, Nigar; Eyigor, Sibel; Sarıdoğan, Merih; Bodur, Hatice; Cantürk, Ferhan; Turhanoğlu, Ayşe; Arslan, Şule; Başaran, Aynur; Küçükoğlu, Selçuk; Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı.; 6603550418Objective: The aim of this study was to evaluate the polypharmacy issue and its correlations with socio-economic variables in Turkish elderly patients. Design: Cross-sectional Setting: Outpatient clinics of the medical schools, departments of physical medicine and rehabilitation from 12 provinces. Participants: A total of 1430 elderly in different geographical regions of Turkey during January 2007 to January 2008 were included. Measurements: Patients were interviewed using a questionnaire that included demographic characteristics, current medical diagnosis, and pharmaceuticals that are used by elderly. Demographical parameters were gender, age, marital status, number of children, level of education, province, and status of retirement. Results: The mean number of drugs was found to be higher in the females. There was a significant difference among age groups, marital status groups, and the number of children categories. The distribution of the number of drugs among education levels did not differ significantly, whereas the distribution of the number of drugs between the status of retirement and presence of chronic disease differed significantly. Conclusions: Polypharmacy is correlated with various factors including age, sex, marital status, number of children, status of retirement, and presence of chronic medical conditions but not educational status in our study group.Item Quality of life and related variables in patients with ankylosing spondylitis(Springer, 2011-05) Bodur, Hatice; Ataman, Şebnem; Rezvani, Aylin; Buğdaycı, Derya Soy; Çevik, Remzi; Birtane, Murat; Akıncı, Ayşen; Altay, Zuhal; Günaydın, Rezzan; Yener, Mahmut; Koçyiğit, Hikmet; Duruöz, Tuncay; Yazgan, Pelin; Çakar, Engin; Aydın, Gülümser; Hepgüler, Simin; Kırnap, Mehmet; Ölmez, Neşe; Soydemir, Raikan; Kozanoğlu, Erkan; Bal, Ajda; Karkucak, Murat; Günendi, Zafer; Altan, Lale; Sivrioğlu, Koncuy; Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı.; 56245687600; 6603281363To evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]). The mean ASQoL score was 7.1 +/- A 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL. In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales.Item Turkish league against rheumatism national recommendations for the management of ankylosing spondylitis(Romatizmaya Karşı Türk Dili Yayınları, 2011) Bodur, Hatice; Sivas, Filiz; Yılmaz, Özlem; Özgöçmen, Salih; Günaydın, Rezzan; Kaya, Tacıser; Ataman, Şebnem; Altay, Zuhal; Aydoğ, Ece; Birtane, Murat; Borman, Pınar; Buğdaycı, Derya Soy; Bütün, Bülent; Çakırbay, Haşim; Duruöz, Tuncay; Gürer, Gülcan; Hepgüler, Simin; Kamanlı, Ayhan; Kuru, Ömer; Küçükdeveci, Ayşe; Nacir, Barış; Ölmez, Neşe; Rezvani, Aylin; Yanık, Burcu Çörekçi; Altan, Lale; Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı.; AAH-1652-2021; 6603281363Objectives: To develop Turkish League Against Rheumatism (TLAR) National Recommendations for the management of ankylosing spondylitis (AS). Materials and methods: A scientific committee of 25 experts consisting of six rheumatologists and 19 physical medicine and rehabilitation specialists was formed by TLAR. Recommendations were based on the 2006 ASsessment in Ankylosing Spondylitis International Working Group(ASAS)/European League Against Rheumatism (EULAR) recommendations and a systematic review of associated publications between January 2005 and September 2010. A Delphi process was used to develop the recommendations. Twelve major recommendations were constructed for the management of AS. Voting using a numerical rating scale assessed the strength of each recommendation. Results: The 12 recommendations include patient assessment, patient follow-up along with pharmacological and non-pharmacological methods. Some minor additions and changes have been made to the ASAS/EULAR recommendations. All of the recommendations had sufficient strength. Conclusion: National recommendations for the management of AS were developed based on scientific evidence and consensus expert opinion. These recommendations will be updated regularly in accordance with recent developments.