Browsing by Author "Bilgin, E."

Now showing 1 - 3 of 3

Disease characteristics of psoriatic arthritis patients may differ according to age at psoriasis onset: Cross-sectional data from the psoriatic arthritis-international database
(Clinical & Exper Rheumatology, 2021-05-01) Bilgin, E.; Aydin, S. Z.; Tinazzi, I.; Bayindir, O.; Kimyon, G.; Ozisler, C.; Dogru, A.; ; Aksu, K.; Cetin, G. Yildirim; Yilmaz, S.; Solmaz, D.; Omma, A.; Can, M.; Kucuksahin, O.; Yavuz, S.; Ersozlu, E. D.; Kilic, L.; Tarhan, E. F.; Tufan, M. Aydin; Akyol, L.; Cinar, M.; Erden, A.; Gonullu, E.; Yildiz, F.; Bakirci, S.; Erbasan, F.; Esmen, S. Ergulu; Kucuk, A.; Tufan, A.; Balkarli, A.; Mercan, R.; Erten, S.; Akar, S.; Kasifoglu, T.; Duruoz, T.; Yazisiz, V.; Kalyoncu, U.; Dalkılıç, E.; DALKILIÇ, HÜSEYİN EDİZ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı.
ObjectiveTo explore the impact of early versus late-onset psoriasis (PsO) on the disease characteristics of psoriatic arthritis (PsA) in a large-multicentre cohort.MethodsThe data from a multicentre psoriatic arthritis database was analysed. Patients were grouped according to age at psoriasis onset (early onset; 40 years of age, late-onset; 40 years of age) and disease characteristics of the groups were compared by adjusting for BMI and PsA duration, where necessary.ResultsAt the time of analyses, 1634 patients were recruited [62.8% females; early onset 1108 (67.8%); late-onset, 526 (32.2%)]. The late-onset group was more over-weight [66.8% vs. 86.8%, p<0.001; adjusted for age -aOR 1.55 (1.11-2.20; 95% CI)]. The early onset group had more scalp psoriasis at onset (56.7% vs. 43.0%, p<0.001), whereas extremity lesions were more common in the late-onset group (63.8% vs. 74.2%, p<0.001). Axial disease in males and psoriatic disease family history in females were significantly higher in the early onset group [38.0% vs. 25.4%; p=0.005; adjusted for PsA duration -aOR 1.76 (1.19-2.62; 95% CI) / 39.5% vs. 30.1%; p=0.003; OR 1.51 (1.15-1.99; 95% CI), respectively]. Psoriatic disease activity parameters, patient-physician reported outcomes and HAQ-DI scores were similar in both groups.ConclusionClinical features of PsA may be affected by the age at onset of PsO. Different genetic backgrounds in early and late-onset PsO may be driving the differences in psoriasis and PsA phenotypes.
Epidemiological characteristics of viral hepatitis in patients with rheumatic diseases - implications from treasure database
(BMJ Publishing Group, 2022-06-01) Ersözlü, D.; Ekici, M.; Coşkun, B. Nejdet; Badak, S. O.; Bilgin, E.; Kalyoncu, U.; Yağız, Burcu; Pehlivan, Yavuz; Küçükşahin, O.; Erden, A.; Solmaz, D.; Atagündüz, P.; Kimyon, G.; Beş, C.; Çolak, S.; Mercan, R.; Kaşifoğlu, T.; Emmungil, H.; Kanitez, N. A.; Ateş, A.; Koca, S. S.; Kiraz, S.; Ertenli, A. I.; COŞKUN, NEJDET; YAĞIZ, BURCU; PEHLİVAN, YAVUZ; Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Bölümü; FQP-0451-2022; AAG-7155-2021; JQW-5031-2023
Tofacitinib in rheumatoid arthritis-associated interstitial lung disease: Efficacy and safety analysis from treasure real-life data
(Bmj Publishing Group, 2021-06-01) Kalyoncu, U.; Bilgin, E.; Erden, A.; Satis, H.; Tufan, A.; Tekgoz, E.; Ates, A.; Kucuksahin, O.; Yazisiz, V.; Kimyon, G.; Bes, C.; Ertenli, A. I.; Kiraz, S.; Coskun, B. N.; COŞKUN, NEJDET; Yagiz, B.; YAĞIZ, BURCU; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı.; 0000-0003-0298-4157; 0000-0002-0866-1503; JQW-5031-2023; AAG-7155-2021