Browsing by Author "Baechlein, Christine"

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    Presence of bovine hepacivirus in Turkish cattle
    (Elsevier, 2018-09-07) Baechlein, Christine; Becher, Paul; Yeşilbağ, Kadir; Kadiroğlu, Berfin; Toker, Eda Baldan; Alpay, Gizem; Uludağ Üniversitesi/Veteriner Fakültesi/Viroloji Anabilim Dalı.; 0000-0003-2468-3945; 0000-0002-3411-081X; AAH-3875-2021; ABE-7662-2020; ABE-9974-2020; AAH-3917-2021; 6602912127; 57203898812; 57203639421; 54079452300
    Hepatitis C virus (HCV), a worldwide distributed human pathogen, causes one of the most important viral infections in human being. HCV is the type species of the genus Hepacivirus (Flaviviridae) in which recently discovered animal viruses i.e. from horses, bats, rodents and cattle are allocated. After preliminary reports in 2015 from German and African cattle, a wide distribution of bovine hepacivirus (BovHepV, Hepacivirus N) was proposed. We investigated the possible presence of BovHepV in serum samples from cattle in different locations of Turkey. Analyzing a total of 120 samples from 98 female (dairy) and 22 male (beef) cattle by real-time RT-PCR resulted in 15 (12.5%) positives. BovHepV infection was detected in 6 out of 10 locations included in the study. There were positive samples both from eastern and western parts of the country indicating possible wide distribution in the Turkish cattle population. Phylogenetic analysis of 9 selected positive samples clearly assigned 8 sequences to a separate cluster on the basis of NS3 gene region, while one of the sequences obtained from an imported animal from north of Italy grouped with sequences obtained from cattle in Germany. The latter finding may indicate possible occurrence of this genetic group of BovHepV not only in Germany but in other European countries. Results of the present study demonstrate the presence of BovHepV infections in Turkey and in The Middle East region.