Browsing by Author "Aytmirzakizi, Ayperi"

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Comparison of the impacts of medet omidi ne/ke tamin e and medetomidine/propofol anesthesia and their reversal by atipamezole on echocardiographic values in dogs
(Aves, 2022-09-01) Kibar, Murat; Aytmirzakizi, Ayperi; Öztürk, Zeynep; Keskin, Abdulkadir; KESKİN, ABDULKADİR; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Jinekoloji ve Doğum Anabilim Dalı.; 0000-0003-1791-1401
The reaction of the cardiovascular system to anesthetics can be various and different, based on dosing, the experimental model, and agent sele-ction. A few studies have compared the effects of different anesthetic agents used for trans-thoracic echocardiography on cardiac functions in dogs; however, none of these studies examined the effects of different anesthetic regimes and their reversal by atipamezole echoc ardio graph icall y. The aim of this study was to investigate, visualize, and clarify in vivo both the short-term echocardiographic impacts of medet omidi ne-ke tamin e and medet omidi ne-pr opofo l anesthesia regimes and their reversal in dogs. Twenty sexually intact female dogs (weighing between 5.7 and 14.5 kg and 0.5-3 years of age) referred for ovariohysterectomy procedure from a local shelter at regular intervals over 3 months were included in the study. Echocardiographic measurements of the two-dimensional guided M-mode echocardiography were conducted with the dogs positioned in right lateral recumbence. Both groups showed declines in interventricu-lar septum percent, left ventricular diameter percent, and left ventricular ejection fraction after anesthesia induction (baseline vs. T1, all, p < .05); nevertheless, the reduction and starting pattern of interventricular septum percent, left ventricular diameter percent, and left ventricular ejection fra-ction presented important intergroup distinction. The echocardiographic values were affected significantly after anesthesia with medet omidine- ketamin e and medet omidi ne-pr opofo l; atipamezole can be useful for return to baseline values quickly and safely in dogs after abdominal sur-gery such as ovariohysterectomy.
The detection and phylogenetic analysis of Anaplasma phagocytophilum-like 1, A. ovis and A. capra in sheep: A. capra divides into two genogroups
(Springer, 2022-09-28) Altay, Kursat; Erol, Ufuk; Şahin, Ömer Faruk; Aytmirzakizi, Ayperi; Temizel, Ethem Mutlu; Aydin, Mehmet Fatih; Dumanlı, Nazir; Aktaş, Münir; TEMİZEL, ETHEM MUTLU; Bursa Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı.; ECV-4083-2022
In this study, the presence, prevalence, and genotypes of Anaplasma phagocytophilum, A. ovis, and A. capra in sheep were investigated based on 16 S SSU rRNA, groEL, and gtlA gene-specific polymerase chain reaction (PCR), respectively. The sequences of the genes were used for detection of the phylogenetic position of the species. Additionally, a restriction fragment length polymorphism (RFLP) were carried out for discrimination of A. phagocytophilum and related variants (A. phagocytophilum-like 1 and 2). The prevalence of Anaplasma spp. was found as 25.8% (101/391), while it was found that A. ovis, A. phagocytophilum-like 1, and A. capra are circulating in the sheep herds in Kyrgyzstan, according to the PCRs, RFLP and the partial DNA sequencing results. The positivity rates of A. phagocytophilum-like 1, A. ovis, and A. capra genotype-1 were 6.9, 22.5, and 5.3%, respectively. A total of 32 (8.2%) sheep were found to be mix infected. Moreover, phylogenetic analyses and sequence comparison with those available in the GenBank showed that A. capra formed two distinct genetic groups (A. capra genotype-1 and A. capra genotype-2). Considering the zoonotic potential of these species, it may be necessary to make changes in the interpretation of anaplasmosis cases in animals and there is a need for further studies to determine the pathogenicity of the species/genotypes circulating in animals.