Browsing by Author "Akman, Sema"

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Chronic peritoneal dialysis in Turkish children: A multicenter study
(Springer, 2005-05) Bakkaloğlu, Sevcan A.; Söylemezoğlu, Oğuz; Ekim, Mesiha; Elhan, Atilla H.; Yalçınkaya, Fatoş; Sever, Lale; Çalışkan, Salim; Noyan, Aytül; Anarat, Ali; Aksu, Nejat; Kara, Orhan D.; Akman, Sema; Güven, Ayfer Gür; Öner, Ayşe; Düşünsel, Ruhan; Bakkaloğlu, Aysin; Denizmen, Yasemen; Özçelik, Gül; Dönmez, Osman; Uludağ Üniversitesi/Tıp Fakültesi.; AAA-8778-2021; 19033971800
Chronic peritoneal dialysis (CPD) has been utilized in the treatment of children since 1989 in Turkey. The aims of this study were to summarize our experience with CPD in children and to establish a pediatric registry data system in Turkey. Standard questionnaires were sent to all pediatric CPD centers. 514 patients treated between 1989 and 2002 in 12 pediatric centers were enrolled in the study. Reflux nephropathy was the most common (18.1%) cause of renal failure. Mean age at dialysis initiation was 10.1+/-4.6 years. Mean duration of dialysis was 24.1+/-20.5 months. Continuous ambulatory peritoneal dialysis ( CAPD) was the first CPD modality for 476 (92.6%) patients, 142 of whom switched to automated peritoneal dialysis (APD) during follow-up. Currently, 47.3% of the patients are still on CPD, 15.4% were transplanted, 13.2% switched to hemodialysis, 16.7% died. The patient and technique survivals were 90% and 95% at one year and 70% and 69% at five years, respectively. The survival was significantly shorter in the youngest age group ( 0 - 24 months) compared to those in older age groups ( p= 0.000). We herein report the first results of the TUPEPD study providing information on demographic data and survival of pediatric CPD patients. As opposed to clear recommendations in favor of APD, there is a clear preponderance of CAPD in our pediatric CPD population. That vesicoureteral reflux (VUR) is still the leading cause of renal failure is a distressing finding. Remarkably lower survival rates and transplantation ratios are as striking and distressing as the high incidence of VUR among the causes of ESRD. We conclude that we must make a great effort to achieve better results and to change these undesirable events.
Clinical features of children with chronic non-bacterial osteomyelitis: A multicenter retrospective case series from Turkey
(Turkish League Against Rheumatism, 2021-09-01) Acari, Ceyhun; Comak, Elif; Turkucar, Serkan; Dundar, Hatice Adiguzel; Akman, Sema; Makay, Balahan; Unsal, Sevket Erbil; Cekic, Sukru; ÇEKİÇ, ŞÜKRÜ; Kilic, Sara Sebnem; KILIÇ GÜLTEKİN, SARA ŞEBNEM; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.; 0000-0002-9574-1842; 0000-0001-8571-2581; 0000-0001-7131-8911; ACH-9790-2022; L-1933-2017; C-1860-2016; JZU-0721-2024; AAH-1658-2021; HQZ-1577-2023; C-1642-2016
Objectives: This study aims to evaluate demographic, clinical, and radiological characteristics of Turkish children with chronic non-bacterial osteomyelitis.Patients and methods: Between January 2008 and December 2018, a total of 28 patients (10 males, 18 females; median age: 12.5 years; range, 4.5 to 21 years) who were diagnosed with chronic non-bacterial osteomyelitis in three pediatric rheumatology centers were retrospectively analyzed. The demographic, clinical, and laboratory findings of the patients were recorded.Results: The median age at the time of diagnosis was 10.2 years. The median time from symptom onset to diagnosis was 6.5 months. The median follow-up was 18.5 months. The most frequent symptom at onset was arthralgia (75.0%). The most frequently involved bone was the femur (67.9%). Eight (63.6%) of 12 patients had at least one Mediterranean fever gene (MEFV) mutation, indicating a significantly higher prevalence than the Turkish population (14.8%). Five of these patients fulfilled the diagnostic criteria for familial Mediterranean fever (FMF). All patients received non-steroidal anti-inflammatory drugs. Other drugs were methotrexate (46.4%), sulfasalazine (39%), corticosteroids (25%), anti-tumor necrosis factor (anti-TNF) agents (32%), pamidronate (25%), and colchicine (21.4%). Six of eight patients with MEFV mutations were administered with colchicine, and all of them responded to treatment.Conclusion: Clinical evolution and imaging investigations should be carefully performed to prevent any delay in the diagnosis of patients with chronic non-bacterial osteomyelitis. Based on our study results, FMF coexistence is worth investigating in patients with chronic non-bacterial osteomyelitis, particularly in the Turkish population.
Covid-19 in pediatric nephrology centers in Turkey
(Springer, 2021-10-01) Bakkaloglu, Sevcan A.; Atikel, Yesim Ozdemir; Leventoğlu, Emre; Nalcacioglu, Hulya; Dursun, IsmaIl; PoyrazoGlu, Hakan; Dursun, Hasan; Yildirim, Zeynep Yuruk; Yildiz, Nurdan; Aksoy, Gulsah Kaya; Akman, Sema; Tasdemir, Mehmet; Bilge, Ilmay; Celakil, Mehtap; Kilic, Beltinge Demircioglu; Selcuk, Senay Zirhli; Canpolat, Nur; Cakici, Evrim Kargin; Ozlu, Sare Gulfem; Tulpar, Sebahat; Yuksel, Selcuk; Atmis, Bahriye; Doven, Serra Surmeli; Taner, Sevgin; Ertan, Pelin; Kavaz, Asli; Bayram, Meral Torun; Kalyoncu, Mukaddes; GUlleroGlu, Kaan; Kabasakal, Caner; Demir, Belde Kasap; Cicek, Rumeysa Yasemin; Donmez, Osman; Kara, Aslihan; Yavascan, Onder; Ozcelik, Gul; Yildirim, Deniz Gezgin; Guler, Muhammet Akif; Sonmez, Ferah; Topaloglu, Rezan; Alpay, Harika; Dönmez, Osman; DÖNMEZ, OSMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; 0000-0001-6530-9672; 0000-0001-5304-3125; 0000-0002-0504-7911; 0000-0002-0686-9714; 0000-0002-0191-4344; 0000-0003-2891-2231; 0000-0003-0293-1581; 0000-0001-7131-8911; 0000-0002-5579-6339; 0000-0002-4852-989X; 0000-0002-1697-6206; 0000-0001-9415-1640; 0000-0001-9109-859X; 0000-0002-2994-7201; 0000-0003-1434-3824; 0000-0003-4410-0444; 0000-0001-9394-2977; 0000-0002-6423-0927; GQP-4951-2022; F-3294-2013; AAA-8957-2021; JLL-9304-2023; JCE-7313-2023; C-5473-2015; AAJ-8833-2021; AAW-7097-2020; AAP-7394-2020; HTL-5515-2023; L-1713-2016; JDW-3813-2023; AAM-2913-2021; C-1642-2016; W-7320-2018; V-7413-2017; AAA-4023-2020; IAP-2930-2023; GSI-4238-2022; AAE-1511-2020; HCH-8357-2022; JAO-2810-2023; JYQ-2668-2024
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2023-03-24) Kisaarslan, Aysenur Pac; Cicek, Sumeyra Ozdemir; Batu, Ezgi D.; Sahin, Sezgin; Gurgoze, Metin K.; Cetinkaya, Sibel Balci; Ekinci, Miray Kisla; Atmis, Bahriye; Barut, Kenan; Adrovic, Amra; Agar, Buket Esen; Sahin, Nihal; Demir, Ferhat; Baglan, Esra; Kara, Mehtap Akbalik; Selcuk, Senay Zirhli; Ozdel, Semanur; Comak, Elif; Akkoyunlu, Betuel; Yener, Guelcin Otar; Yildirim, Deniz Gezgin; Ozturk, Kubra; Yildiz, Mehmet; Haslak, Fatih; Sener, Seher; Kisaoglu, Hakan; Baba, Oezge; Kizildag, Zehra; Isguder, Rana; Caglayan, Senguel; Bilgin, Raziye B. Gueven; Aytac, Guelcin; Yucel, Burcu Bozkaya; Tanatar, Ayse; Sonmez, Hafize E.; Cakan, Mustafa; Kara, Aslihan; Elmas, Ahmet T.; Kilic, Beltinge Demircioglu; Ayaz, Nuray Aktay; Kasap, Belde; Acar, Banu Celikel; Ozkaya, Ozan; Yueksel, Selcuk; Bakkaloglu, Sevcan; Aydog, Ozlem; Aksu, Guzide; Akman, Sema; Donmez, Osman; Bulbul, Mehmet; Buyukcelik, Mithat; Tabel, Yilmaz; Sozeri, Betuel; Kalyoncu, Mukaddes; Bilginer, Yelda; Poyrazoglu, Muammer H.; Unsal, Erbil; Kasapcopur, Ozgur; Ozen, Seza; Dusunsel, Ruhan; AKKOYUNLU, BETÜL; DÖNMEZ, OSMAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Nefroloji ve Romatoloji Anabilim Dalı.; JHC-5766-2023; IRG-7973-2023
Introduction: Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE). Aim: To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population. Methods: This study was based upon 24 referral centers' SLE cohorts, multicenter and multidisciplinary network in Turkey. Patient data were collected by a case report form which was standardized for NP definitions according to American Collage of Rheumatology (ACR). Systemic Lupus International Collab-orating Clinics/American College of Rheumatology Damage Index (SDI) neuropsychiatric part was used to determine NP damage. Variables were evaluated Ward's hierarchical clustering analyses, univariate, and multivariate logistic regression analyses. Results: A hundred forty-nine of 1107 jSLE patients had NP involvement (13.5%). The most common NPSLE findings were headache (50.3%), seizure (38.3%), and acute confusional state (33.6%). Five clusters were identified with all clinical and laboratory findings. The first two clusters involved neuropathies, demyelinating diseases, aseptic meningitis, and movement disorder. Cluster 3 involved headache, activ-ity markers and other SLE involvements. Idiopathic intracranial hypertension, cerebrovascular disease, cognitive dysfunction, psychiatric disorders and SLE antibodies were in the fourth, and acute confusional state was in the fifth cluster. In multivariate analysis, APA positivity; OR: 2.820, (%95CI: 1.002-7.939), P: 0,050, plasmapheresis; OR: 13.804 (%95CI: 2.785-68.432), P: 0,001, SLEDAI scores; OR: 1.115 (%95CI: (1.049-1.186), P: 0,001 were associated with increased risk for neurologic sequelae. Conclusion: We detected the prevalence of juvenile NPSLE manifestations in Turkey. We have identified five clusters that may shed light pathogenesis, treatment and prognosis of NP involvements. We also determined risk factors of neurological sequelae. Our study showed that new definitions NP involvements and sequelae for childhood period are needed. (c) 2023 Socie ' te ' franc,aise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.