Brain abscess and cystic brain tumor - Discrimination with dynamic susceptibility contrast perfusion-weighted MRI

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dc.contributor.buuauthorErdoğan, Cüneyt
dc.contributor.buuauthorHakyemez, Bahattin
dc.contributor.buuauthorYıldırım, Nalan
dc.contributor.buuauthorParlak, Mufit
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-3425-0740tr_TR
dc.contributor.researcheridAAI-2318-2021tr_TR
dc.date.accessioned2021-06-30T10:37:46Z
dc.date.available2021-06-30T10:37:46Z
dc.date.issued2005
dc.description.abstractDifferentiating between brain abscesses and cystic brain tumors such as high-grade gliomas and metastases is often difficult with conventional MRI. The goal of this study was to evaluate the diagnostic utility of perfusion MRI to differentiate between these pathologies. MRI was performed in 19 patients with rim-enhancing brain lesions (4 pyogenic abscesses, 8 high-grade gliomas, 7 metastases). In addition to standard MR sequences, trace diffusion-weighted MRI with apparent diffusion coefficient (ADC) maps and perfusion-weighted MRI by using a first-pass gadopentetate dimeglumine T2*-weighted gradient echo single-shot echo-planar sequence were performed. Relative cerebral blood volume (rCBV) ratios were obtained via the values of the capsular portions of the lesions and the normal white matter. All the abscesses had markedly hyperintense signals in trace diffusion images, whereas they had significant hypointense signals in ADC images. In perfusion-weighted images, the capsular portions of the abscesses demonstrated low colored areas compared with the normal white matter and the rCBV ratio calculated was 0.76 +/- 0.12 (mean +/- SD). All but two of the cystic tumors showed low signal intensity on trace diffusion-weighted images and high signal intensity on ADC maps. Hyperintense signal was found in two brain tumors mimicking brain abscesses on trace diffusion images. The rCBV values in high-grade gliomas and metastases were 5.51 +/- 2.08 and 4.58 +/- 2.19, respectively. The difference between abscesses and cystic tumors was statistically significant (P = 0.003). Perfusion MRI may allow the differentiation of pyogenic brain abscess from cystic brain tumors, making it a strong additional imaging modality in the early diagnosis of these two entities.en_US
dc.identifier.citationErdoğan, C. vd. (2005). "Brain abscess and cystic brain tumor - Discrimination with dynamic susceptibility contrast perfusion-weighted MRI". Journal of Computer Assisted Tomography, 29(5), 663-667.tr_TR
dc.identifier.endpage667tr_TR
dc.identifier.issn0363-8715
dc.identifier.issue5tr_TR
dc.identifier.pubmed16163039tr_TR
dc.identifier.scopus2-s2.0-25844509264tr_TR
dc.identifier.startpage663tr_TR
dc.identifier.urihttps://doi.org/10.1097/01.rct.0000168868.50256.55
dc.identifier.urihttps://journals.lww.com/jcat/Fulltext/2005/09000/Brain_Abscess_and_Cystic_Brain_Tumor_.19.aspx
dc.identifier.urihttp://hdl.handle.net/11452/20930
dc.identifier.volume29tr_TR
dc.identifier.wos000232173300019tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.journalJournal of Computer Assisted Tomographyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBrainen_US
dc.subjectDiffusionen_US
dc.subjectNeoplasmen_US
dc.subjectAbscessen_US
dc.subjectMagnetic resonanceen_US
dc.subjectPerfusionen_US
dc.subjectDiffusionen_US
dc.subjectAIDSen_US
dc.subjectLymphomaen_US
dc.subjectToxoplasmosisen_US
dc.subjectRadiologyen_US
dc.subjectNuclear medicine & medical imagingen_US
dc.subject.wosRadiology, nuclear medicine & medical imagingen_US
dc.titleBrain abscess and cystic brain tumor - Discrimination with dynamic susceptibility contrast perfusion-weighted MRIen_US
dc.typeArticle

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