Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report

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dc.contributor.buuauthorKarkucak, Mutlu
dc.contributor.buuauthorYakut, Tahsin
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorGülten, Tuna
dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genel Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatrik Hematoloji Anabilim Dalı.tr_TR
dc.contributor.scopusid35388323500tr_TR
dc.contributor.scopusid6602802424tr_TR
dc.contributor.scopusid6506622162tr_TR
dc.contributor.scopusid6505944216tr_TR
dc.contributor.scopusid24072843300tr_TR
dc.date.accessioned2022-11-07T13:45:48Z
dc.date.available2022-11-07T13:45:48Z
dc.date.issued2011
dc.description.abstractFluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL). Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Near-tetraploidy. Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.en_US
dc.description.abstractPre- B Akut Lenfoblastik Lösemi tanısı konulan 11 yaşında erkek olguda, Floresans insitu hibridizasyon analizinde t(12;21)(p13;q22) translokasyonu ve near-tetraploidi beraber olduğu gösterilmiştir. Bazı çalışmalarda t(12;21)(p13;q22) trans lokasyonunun iyi prognostik etki oluşturduğu belirtmelerine rağmen near-tetraploidinin prognostik etkisi hakkında çok az bil gi vardır. Burada Pre-B Akut Lenfoblastik Lösemili olguda t(12;21)(p13;q22) translokasyonu ile birlikte near tetraplodi bulgu larının birlikte etkisi tartışılmaktadır.tr_TR
dc.identifier.citationKarkucak, M. vd. (2011). "Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report". UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, 21(3), 192-195.tr_TR
dc.identifier.endpage195tr_TR
dc.identifier.issn1306-133X
dc.identifier.issue3tr_TR
dc.identifier.scopus2-s2.0-80053646851tr_TR
dc.identifier.startpage192tr_TR
dc.identifier.urihttps://doi.org/10.4999/uhod.09122
dc.identifier.urihttp://www.uhod.org/pdf/PDF_479.pdf
dc.identifier.urihttp://hdl.handle.net/11452/29422
dc.identifier.volume21tr_TR
dc.identifier.wos000295573200011tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.trdizinTrDizintr_TR
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherAkad Doktorlar Yayınevitr_TR
dc.relation.journalUHOD - Uluslararası Hematoloji-Onkoloji Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOncologyen_US
dc.subjectChildhood acute lymphoblastic leukemiaen_US
dc.subjectNear-tetraploidyen_US
dc.subjectT(12;21)en_US
dc.subjectMoleculageneticsen_US
dc.subjectHyperdiploidyen_US
dc.subjectTel-aml1en_US
dc.subjectChildrenen_US
dc.subjectÇocukluk çağı akut lenfoblastik lösemitr_TR
dc.subjectNear-Tetraplodi, t(12;21)tr_TR
dc.subject.emtreeAntineoplastic agent EMTREE medical termsen_US
dc.subject.emtreeAcute lymphoblastic leukemiaen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCase reporten_US
dc.subject.emtreeChilden_US
dc.subject.emtreeChildhood leukemiaen_US
dc.subject.emtreeChromosome 13pen_US
dc.subject.emtreeChromosome translocation 12en_US
dc.subject.emtreeCytogeneticsen_US
dc.subject.emtreeFluorescence in situ hybridizationen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLaboratory testen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreeRelapseen_US
dc.subject.emtreeSchool childen_US
dc.subject.emtreeTetraploidyen_US
dc.subject.emtreeTreatment responseen_US
dc.subject.scopusAcute Lymphoblastic Leukemia; Chromosome 21; Pre B Lymphocyteen_US
dc.subject.wosOncologyen_US
dc.titleChildhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case reporten_US
dc.title.alternativet(12;21)(p13;q22) translokasyonu ve Near Tetraplodi bulunan çocukluk çağı akut lenfoblastik lösemili bir olgu sunumutr_TR
dc.typeArticle
dc.wos.quartileQ4en_US

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