Kedi enfeksiyonları 1: Zorlayan tanı; kedilerin enfeksiyöz peritonitisi
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Date
2009-04-29
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Uludağ Üniversitesi
Abstract
Feline infectious peritonitis (FIP) kedi koronaviruslerinin (FCoV) virulent ve mutant bir formu tarafından oluşturulan, sistemik bir hastalıktır. Genç kedilerdeki en önemli ölüm nedeni olduğu bildirilmektedir. Bu virusun mutantı olduğu koronavirusler (FCoV), genellikle patojenik değildirler ya da bazı olgularda sadece hafif ishale neden olabilirler. Bu iki suş, birbirlerinden morfolojik ya da antijenik olarak ayrılamazlar. Bu nedenle FIP’in tanısı çok zordur. Olası tanı, klinik bulgular ve bazı kan parametrelerindeki karakteristik değişiklikler sonucunda koyulur. Tanıyı kesinleştirmek tek bir test temelinde mümkün değildir. Klinik bulgular, laboratuar bulguları ve seroloji birlikte değerlendirilmelidir. Enfeksiyonun kesin tedavisi yoktur. En etkin tedavi kedilere özgü interferon omega uygulanmasıdır. Mevcut tek aşı vardır ancak etkinliği tartışmalıdır ve diğer aşılar gibi % 100 etkili olduğu söylenemez.
Feline infectious peritonitis (FIP) is a systemic disease induced by virulent mutant forms of Feline Coronavirus (FCoV) and is a major infectious cause of mortality in young cats. This virus is a mutation of the Feline Enteric Coronavirus (FECV) that is either non-pathogenic or causes only mild intestinal disease. Those two strains can not be distinguished from one another morphologically or antigenically. This is what makes FIP diagnosis so challenging. The diagnosis of feline infectious peritonitis in most patients is complicated. Currently the presumptive diagnosis of FIP is based on clinical data and characteristic changes in some blood parameters. No single laboratory test is reliable for the diagnosis.It should never be based solely on one diagnostic test. Clinical signs, laboratory findings, and serologic testing that need to be considered. The most effective treatment, feline interferon omega,. There is currently only one FIP vaccine, and, like all vaccines, it is not 100% effective.
Feline infectious peritonitis (FIP) is a systemic disease induced by virulent mutant forms of Feline Coronavirus (FCoV) and is a major infectious cause of mortality in young cats. This virus is a mutation of the Feline Enteric Coronavirus (FECV) that is either non-pathogenic or causes only mild intestinal disease. Those two strains can not be distinguished from one another morphologically or antigenically. This is what makes FIP diagnosis so challenging. The diagnosis of feline infectious peritonitis in most patients is complicated. Currently the presumptive diagnosis of FIP is based on clinical data and characteristic changes in some blood parameters. No single laboratory test is reliable for the diagnosis.It should never be based solely on one diagnostic test. Clinical signs, laboratory findings, and serologic testing that need to be considered. The most effective treatment, feline interferon omega,. There is currently only one FIP vaccine, and, like all vaccines, it is not 100% effective.
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Keywords
FIP, Koronavirus, Kedi, Coronavirus, Cat
Citation
Aytuğ, N. (2008). "Kedi enfeksiyonları 1: zorlayan tanı; kedilerin enfeksiyöz peritonitisi". Uludağ Üniversitesi Veteriner Fakültesi Dergisi, 27(1-2), 11-17.