Serum leptin levels correlate with obesity parameters but not with hyperinsulinism in women with polycystic ovary syndrome

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dc.contributor.buuauthorErtürk, Erdinç
dc.contributor.buuauthorKuru, Nesrin
dc.contributor.buuauthorSavcı, Vahide
dc.contributor.buuauthorTuncel, Ercan
dc.contributor.buuauthorErsoy, Canan
dc.contributor.buuauthorİmamoğlu, Şazi
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji Bilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Farmakoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAJ-6536-2021tr_TR
dc.contributor.researcheridAAH-8861-2021tr_TR
dc.contributor.scopusid7005488796tr_TR
dc.contributor.scopusid6602517402tr_TR
dc.contributor.scopusid6603687024tr_TR
dc.contributor.scopusid7006929833tr_TR
dc.contributor.scopusid6701485882tr_TR
dc.contributor.scopusid6602297533tr_TR
dc.date.accessioned2022-03-14T07:47:38Z
dc.date.available2022-03-14T07:47:38Z
dc.date.issued2004-11
dc.descriptionBu çalışma, 26 Nisan 2003 tarihinde Lyon[Fransa]'da düzenlenen 6. European Congress of Endocrinology'de bildiri olarak sunulmuştur.tr_TR
dc.description.abstractTo examine serum leptin concentrations in obese and lean patients with polycystic ovary syndrome (PCOS) to assess whether the changes in leptin levels are due to obesity or hormonal alterations. Controlled clinical study. Academic research environment. Obese and lean women with PCOS. Blood samples were collected before and after food consumption. Serum leptin and insulin levels. Serum leptin concentrations were significantly correlated with body mass index (r = 0.649) and also with HOMA (r = 0.535). However, after controlling for body mass index in a partial correlation analysis, no significant correlation was found between serum leptin levels and HOMA or hyperinsulinemia. While lean patients with PCOS had a significant correlation between leptin concentrations and obesity parameters, they did not show any significant correlation with insulin resistance parameters. Although leptin concentrations in women with PCOS correlate with insulin resistance/hyperinsulinemia, this is related only to obesity.en_US
dc.identifier.citationErtürk, E. vd. (2004). “Serum leptin levels correlate with obesity parameters but not with hyperinsulinism in women with polycystic ovary syndrome”. Fertility and Sterility, 82(5), 1364-1368.en_US
dc.identifier.endpage1368tr_TR
dc.identifier.issn0015-0282
dc.identifier.issue5tr_TR
dc.identifier.pubmed15533361tr_TR
dc.identifier.scopus2-s2.0-7944229911tr_TR
dc.identifier.startpage1364tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.fertnstert.2004.04.049
dc.identifier.urihttp://hdl.handle.net/11452/24971
dc.identifier.volume82tr_TR
dc.identifier.wos000225128300023tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.indexed.wosCPCISen_US
dc.language.isoenen_US
dc.publisherElsevier Scienceen_US
dc.relation.journalFertility and Sterilityen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararasıtr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObstetrics and gynecologyen_US
dc.subjectReproductive biologyen_US
dc.subjectLeptinen_US
dc.subjectPCOSen_US
dc.subjectInsulin resistanceen_US
dc.subjectPlasma leptinen_US
dc.subjectInsulin-resistanceen_US
dc.subjectOb geneen_US
dc.subjectWeighten_US
dc.subjectExpressionen_US
dc.subjectFaten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBlood samplingen_US
dc.subject.emtreeBody massen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCorrelation analysisen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHyperinsulinemiaen_US
dc.subject.emtreeHyperinsulinismen_US
dc.subject.emtreeInsulin resistanceen_US
dc.subject.emtreeMedical researchen_US
dc.subject.emtreeObesityen_US
dc.subject.emtreeOvary polycystic diseaseen_US
dc.subject.emtreePriority journalen_US
dc.subject.meshAdulten_US
dc.subject.meshBody mass indexen_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHomeostasisen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperinsulinismen_US
dc.subject.meshInsulin resistanceen_US
dc.subject.meshLeptinen_US
dc.subject.meshObesityen_US
dc.subject.meshPolycystic ovary syndromeen_US
dc.subject.scopusLeptin Receptors; Adiponectin; Obesityen_US
dc.subject.wosObstetrics and gynecologyen_US
dc.subject.wosReproductive biologyen_US
dc.titleSerum leptin levels correlate with obesity parameters but not with hyperinsulinism in women with polycystic ovary syndromeen_US
dc.typeArticle
dc.typeProceedings Paper
dc.wos.quartileQ1en_US

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