Value of chemical shift subtraction MRI in characterization of adrenal masses

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dc.contributor.buuauthorSavcı, Gürsel
dc.contributor.buuauthorYazıcı, Zeynep
dc.contributor.buuauthorŞahin, Neslin
dc.contributor.buuauthorAkgöz, Semra
dc.contributor.buuauthorTuncel, Ercan
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.researcheridAAI-2303-2021tr_TR
dc.contributor.researcheridAAH-5481-2021tr_TR
dc.date.accessioned2021-09-01T08:33:46Z
dc.date.available2021-09-01T08:33:46Z
dc.date.issued2006
dc.description.abstractOBJECTIVE. ne purpose of this study was to assess the advantages of the image subtraction technique in chemical shift MRI for the differentiation of adrenal adenomas from nonadenomas. SUBJECTS AND METHODS. Thirty-five patients with 42 adrenal masses (eight metastases and 34 nonfunctioning adenomas) underwent chemical shift MRI using a double-echo fast low-angle shot sequence. Subsequently, opposed-phase chemical shift MR images were subtracted from in-phase images, The subtraction images were assessed quantitatively and qualitatively. For quantitative assessment, the signal intensity values of the adrenal masses were measured by one investigator with manually defined regions of interest. Qualitative assessment of the subtraction images was performed independently by two investigators, who reported their confidence in diagnosing adenomas versus nonadenomas based on signal intensity of the adrenal masses on subtraction images. RESULTS. The mean signal intensities were significantly different between adenomas and metastases on subtraction images (213 vs 18: p < 0.0001). There was no overlap in signal intensities between adenomas and metastatic tumors, The accuracy in distinguishing adenomas from metastatic tumors was 100% if the cutoff value of the signal intensity selected was 36-106. Quantitative results corresponding to 100% specificity were also observed, with similar sensitivity. No difference in interpretation between the two investigators occurred. CONCLUSION. Chemical shift subtraction MRI provides a high confidence level in distinguishing adrenal adenomas from adrenal metastases. The image subtraction technique also facilitates quantitative and qualitative evaluation of adrenal masses in chemical shift MRI.en_US
dc.identifier.citationSavcı, G. vd. (2006). ''Value of chemical shift subtraction MRI in characterization of adrenal masses''. American Journal of Roentgenology, 186(1), 130-135.en_US
dc.identifier.endpage135tr_TR
dc.identifier.issn0361-803X
dc.identifier.issue1tr_TR
dc.identifier.pubmed16357391tr_TR
dc.identifier.scopus2-s2.0-33644846085tr_TR
dc.identifier.startpage130tr_TR
dc.identifier.urihttps://doi.org/10.2214/AJR.04.1370
dc.identifier.urihttps://www.ajronline.org/doi/10.2214/AJR.04.1370
dc.identifier.urihttp://hdl.handle.net/11452/21595
dc.identifier.volume186tr_TR
dc.identifier.wos000234327000025tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherAmer Roentgen Ray Socen_US
dc.relation.journalAmerican Journal of Roentgenologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRadiology, nuclear medicine & medical imagingen_US
dc.subjectMRI techniqueen_US
dc.subjectMRIen_US
dc.subjectGenitourinary tract imagingen_US
dc.subjectAdrenal glanden_US
dc.subjectAbdomenen_US
dc.subjectCTen_US
dc.subjectTumorsen_US
dc.subjectBenignen_US
dc.subjectDistinctionen_US
dc.subjectDifferentiationen_US
dc.subjectAdenomasen_US
dc.subject.wosRadiology, nuclear medicine & medical imagingen_US
dc.titleValue of chemical shift subtraction MRI in characterization of adrenal massesen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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