Contribution of (99)mTc-sestamibi infusion SPECT to the characterization of fixed perfusion defects

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dc.contributor.buuauthorAkpınar, Ali T.
dc.contributor.buuauthorBaran, İbrahim
dc.contributor.buuauthorGüllülü, Sümeyye
dc.contributor.buuauthorGüneş, Neşe
dc.contributor.buuauthorSaltan, Yelda
dc.contributor.buuauthorAlper, Eray
dc.contributor.buuauthorÖzdemir, Bülent
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nükleer Tıp ve Kardiyoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAJ-8660-2021tr_TR
dc.contributor.scopusid14324350600tr_TR
dc.contributor.scopusid35572557400tr_TR
dc.contributor.scopusid57204660708tr_TR
dc.contributor.scopusid34975332000tr_TR
dc.contributor.scopusid23499465200tr_TR
dc.contributor.scopusid7006827670tr_TR
dc.contributor.scopusid7004168959tr_TR
dc.date.accessioned2022-01-24T09:21:17Z
dc.date.available2022-01-24T09:21:17Z
dc.date.issued2006-08
dc.description.abstractIn patients with coronary artery disease, the distinction between scar and viable myocardium by means of myocardial perfusion imaging (MPI) sometimes can be difficult because of the equivocal meaning of fixed perfusion defects. In this study we examined whether addition of a Tc-99m-sestamibi infusion study to the standard MPI could provide extra information regarding the fixed defects. Thirty-seven patients underwent standard MPI and an extra SPECT study in which Tc-99m-sestamibi was given as a prolonged constant infusion. Of R4 myocardial segments available for analysis, 134 had fixed or resting perfusion abnormalities on standard MPI studies, of which 25% (33/134) in 12 patients showed partial improvement in the perfusion pattern whereas in 6% (8/134) the improvement was very significant in infusion studies. In 19 patients who were also examined with dobutamine echocardiography, 13 showed concordance between echocardiography and infusion MPI. This study suggests that infusion MPI may provide complementary information to the conventional scintigraphy with regard to interpretation of standard myocardial perfusion scans with fixed defects.en_US
dc.identifier.citationAkpınar, A. T. vd. (2006). ''Contribution of (99)mTc-sestamibi infusion SPECT to the characterization of fixed perfusion defects''. Annals of Nuclear Medicine, 20(7), 471-475.en_US
dc.identifier.endpage475tr_TR
dc.identifier.issn0914-7187
dc.identifier.issn1864-6433
dc.identifier.issue7tr_TR
dc.identifier.pubmed17037279tr_TR
dc.identifier.scopus2-s2.0-33749597953tr_TR
dc.identifier.startpage471tr_TR
dc.identifier.urihttps://doi.org/10.1007/BF02987256
dc.identifier.urihttps://link.springer.com/article/10.1007%2FBF02987256
dc.identifier.urihttp://hdl.handle.net/11452/24251
dc.identifier.volume20tr_TR
dc.identifier.wos000240638800004tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.journalAnnals of Nuclear Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRadiology, nuclear medicine & medical imagingen_US
dc.subjectMyocardial viabilityen_US
dc.subjectMyocardial perfusion imagingen_US
dc.subjectFixed defectsen_US
dc.subjectHistopathologyen_US
dc.subjectTechnetium-99m-sestamibien_US
dc.subjectTL-201en_US
dc.subjectIdentificationen_US
dc.subjectContractile reserveen_US
dc.subjectHibernating myocardiumen_US
dc.subjectViable myocardiumen_US
dc.subjectMyocardial viabilityen_US
dc.subjectCoronary-artery-diseaseen_US
dc.subjectLeft-ventricular dysfunctionen_US
dc.subject.emtreeRadiopharmaceutical agenten_US
dc.subject.emtreeMethoxy isobutyl isonitrile technetium tc 99men_US
dc.subject.emtreeDiagnostic agenten_US
dc.subject.emtreeDobutamineen_US
dc.subject.emtreeSingle photon emission computer tomographyen_US
dc.subject.emtreePerfusionen_US
dc.subject.emtreePathologyen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeMethodologyen_US
dc.subject.emtreeMetabolismen_US
dc.subject.emtreeMagnetic resonance angiographyen_US
dc.subject.emtreeHeart muscleen_US
dc.subject.emtreeEchocardiographyen_US
dc.subject.emtreeCoronary artery atherosclerosisen_US
dc.subject.emtreeSingle photon emission computer tomographyen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeMedical researchen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeIschemic heart diseaseen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHeart muscle perfusionen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeElectrocardiogramen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAdulten_US
dc.subject.meshTomography, emission-computed, single-photonen_US
dc.subject.meshTechnetium Tc 99m sestamibien_US
dc.subject.meshRadiopharmaceuticalsen_US
dc.subject.meshPerfusionen_US
dc.subject.meshMyocardiumen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshMaleen_US
dc.subject.meshMagnetic resonance angiographyen_US
dc.subject.meshHumansen_US
dc.subject.meshFemaleen_US
dc.subject.meshEchocardiographyen_US
dc.subject.meshCoronary arteriosclerosisen_US
dc.subject.meshAgeden_US
dc.subject.meshAdulten_US
dc.subject.scopusHeart Left Ventricle Failure; Cardiac Muscle; Hibernationen_US
dc.subject.wosRadiology, nuclear medicine & medical imagingen_US
dc.titleContribution of (99)mTc-sestamibi infusion SPECT to the characterization of fixed perfusion defectsen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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