Necrotizing pneumonia in children

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dc.contributor.buuauthorHacımustafaoğlu, Mustafa
dc.contributor.buuauthorSarımehmet, Handan
dc.contributor.buuauthorGürpınar, Arif Nuri
dc.contributor.buuauthorErcan, İlker
dc.contributor.buuauthorÇelebi, Solmaz
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-2382-290Xtr_TR
dc.contributor.scopusid6602154166tr_TR
dc.contributor.scopusid7006095295tr_TR
dc.contributor.scopusid6507052972tr_TR
dc.contributor.scopusid7004350616tr_TR
dc.contributor.scopusid6603789069tr_TR
dc.date.accessioned2021-08-23T07:01:39Z
dc.date.available2021-08-23T07:01:39Z
dc.date.issued2004-09
dc.description.abstractAim: Clinical features and outcome of 36 patients with necrotizing pneumonia (NP) as well as 36 children with parapneumonic effusions (PPE) and 36 with severe control pneumonia (CP) were investigated. The mean age of the patients in the NP, PPE and CP groups were similar (3.8+/-3.3 (mean+/-SD), 4.2+/-3.0 and 4.2+/-3.0 y, respectively (p>0.05)). The duration of symptoms at presentation were 11.9+/-8.5, 9.2+/-7.2 and 6+/-3.6 d, respectively (p<0.01). The diagnosis of NP was established by computerized tomography. The mean (mean +/- SD) laboratory results in patients with NP revealed a white blood cell (WBC) count of 19300 +/- 8700/mm(3), erythrocyte sedimentation rate (ESR) of 71 +/- 22 mm/h, C-reactive protein (CRP) of 13.6 +/- 11.7 mg/dl and aspartate aminotransferase (AST) of 66 +/- 132 U/L. The values of WBC, ESR, CRP and AST in the NP group were significantly higher than those of the other groups (p<0.001). The duration of hospitalization in the NP, PPE and CP groups was 26+/-9, 16+/-6 and 10+/-5 d, respectively (p<0.001). The number of febrile days was 8 +/- 4, 4 +/- 3 and 3 +/- 3 (p<0.001), and the duration of normalization of CRP was 14+/- 4, 11+/-4 and 7+/-3 d (p<0.001), respectively. The average cost of treatment was US$3476, 1646 and 844, respectively (p<0.001). Conclusion: All NP patients except two (94%) were complicated with PPE. The effusion in patients with NP and PPE was complicated with bronchopleural fistula (55% and 0%, respectively, p<0.001). Surgical treatment was required in 66%, 8% and 0% in patients with NP, PPE and CP, respectively (p<0.001). The mortality rate was 5.5%, 2.7% and 0% (p>0.05).en_US
dc.identifier.citationHacımustafaoğlu, M. vd. (2004). “Necrotizing pneumonia in children”. Acta Paediatrica, 93(9), 1172-1177.en_US
dc.identifier.endpage1177tr_TR
dc.identifier.issn0803-5253
dc.identifier.issue9tr_TR
dc.identifier.pubmed15384879tr_TR
dc.identifier.scopus2-s2.0-4143152842tr_TR
dc.identifier.startpage1172tr_TR
dc.identifier.urihttps://doi.org/10.1080/08035250410026699
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1651-2227.2004.tb02744.x
dc.identifier.urihttp://hdl.handle.net/11452/21512
dc.identifier.volume93tr_TR
dc.identifier.wos000223621500009tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopustr_TR
dc.indexed.wosSCIEtr_TR
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalActa Paediatricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPediatricsen_US
dc.subjectNecrotizing pneumoniaen_US
dc.subjectParapneumonic effusionen_US
dc.subjectPneumoniaen_US
dc.subjectPulmonary gangreneen_US
dc.subject.emtreeAspartate aminotransferaseen_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeBronchopleural fistulaen_US
dc.subject.emtreeChilden_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeClinical featureen_US
dc.subject.emtreeComputer assisted tomographyen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCost benefit analysisen_US
dc.subject.emtreeDisease durationen_US
dc.subject.emtreeEffusionen_US
dc.subject.emtreeErythrocyte sedimentation rateen_US
dc.subject.emtreeFeveren_US
dc.subject.emtreeHospitalizationen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInfanten_US
dc.subject.emtreeLaboratory testen_US
dc.subject.emtreeLength of stayen_US
dc.subject.emtreeLeukocyte counten_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreePneumoniaen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProtein blood levelen_US
dc.subject.emtreeSurgical techniqueen_US
dc.subject.meshAdolescenten_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshChilden_US
dc.subject.meshChild, preschoolen_US
dc.subject.meshHealth care costsen_US
dc.subject.meshHematologic testsen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshLength of stayen_US
dc.subject.meshLungen_US
dc.subject.meshNecrosisen_US
dc.subject.meshPleural effusionen_US
dc.subject.meshPneumoniaen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective studiesen_US
dc.subject.scopusLung Abscess; Necrotizing Pneumonia; Empyemaen_US
dc.subject.wosPediatricsen_US
dc.titleNecrotizing pneumonia in childrenen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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