Tüberkulum sella meningiomalı gebe kadında görme kaybı
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Date
2011-01-19
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Uludağ Üniversitesi
Abstract
Gebe kadınlarda meningioma görülme insidansı,normal kadın popülasyonuna göre daha düşüktür fakat gebelikte meningiomaya bağlı semptomlar artabilirler. 34 yaşında bayan hasta gebeliğinin onuncu haftasında; 4 haftadır sol gözünde başlayan görme kaybıyla başvurdu. Kranial MRI görüntülerinde; suprasellar sisterna ve sella içini doldurmuş, dural kuyruğu olan kitle lezyonu mevcuttu.Hasta operasyona alınarak, tuberkulum sella meningioması total çıkartıldı. İmmünohistokimyasal analizinde; meningioma hücrelerinin % 80 olarak progesteron reseptörü taşıdığı gösterildi. Tuberkulum sella meningiomalı gebe kadınlarda; pozitif progesteron reseptörüne ve hipofiz bezinin büyümesine bağlı olarak ani görme kaybı gerçekleşebilmektedir.
The incidence of meningioma in pregnant women is lower than non-pregnant women of the same age. However, symptoms may worsen during pregnancy. A 34-years old woman in her fourth pregnancy presented at 10 weeks of gestation with a 4 weeks history of progressive visual loss in her left eye. MRI revealed mass lesion that filled the suprasellar cistern and extended into the sella with dural tail. The patient underwent operation and a tuberculum sellae meningioma was removed totally. The immunohistochemical analysis showed positive staining for progesterone receptors in 80% of meningioma cells. The rapid growth of the mass that stains positive for progesterone receptors and the enlargement of the pituitary gland because of the hormonal changes during pregnancy in cases with tuberculum sellae meningioma can cause sudden visual loss.
The incidence of meningioma in pregnant women is lower than non-pregnant women of the same age. However, symptoms may worsen during pregnancy. A 34-years old woman in her fourth pregnancy presented at 10 weeks of gestation with a 4 weeks history of progressive visual loss in her left eye. MRI revealed mass lesion that filled the suprasellar cistern and extended into the sella with dural tail. The patient underwent operation and a tuberculum sellae meningioma was removed totally. The immunohistochemical analysis showed positive staining for progesterone receptors in 80% of meningioma cells. The rapid growth of the mass that stains positive for progesterone receptors and the enlargement of the pituitary gland because of the hormonal changes during pregnancy in cases with tuberculum sellae meningioma can cause sudden visual loss.
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Keywords
Tuberkulum sella, Tuberculum sellae, Meningioma, Gebelik, Progesteron, Görme kaybı, Meningioma, Pregnancy, Progesterone, Visual loss
Citation
Kuytu, T. vd. (2010). "Tüberkulum sella meningiomalı gebe kadında görme kaybı" Uludağ Üniversitesi Tıp Fakültesi Dergisi, 36(3),117-119.