Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study

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dc.contributor.authorHatun, Şükrü
dc.contributor.authorDemirbilek, Hüseyin
dc.contributor.authorDarcan, Şükran
dc.contributor.authorYüksel, Ayşegül
dc.contributor.authorBinay, Çiğdem
dc.contributor.authorŞimşek, Damla Gökşen
dc.contributor.authorKara, Cengiz
dc.contributor.authorÇetinkaya, Ergün
dc.contributor.authorÜnüvar, Tolga
dc.contributor.authorUçaktürk, Ahmet
dc.contributor.authorTütüncüler, Filiz
dc.contributor.authorCesur, Yaşar
dc.contributor.authorBundak, Ruveyde
dc.contributor.authorŞimşek, Enver
dc.contributor.authorBereket, Abdullah
dc.contributor.buuauthorSağlam, Halil
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Endokrinolojisi Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-0710-5422tr_TR
dc.contributor.researcheridC-7392-2019tr_TR
dc.contributor.scopusid35612700100tr_TR
dc.date.accessioned2022-12-13T12:25:48Z
dc.date.available2022-12-13T12:25:48Z
dc.date.issued2016-04-21
dc.description.abstractAims: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. Methods: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3 months of data collection period between October 2012 and July 2013. Results: Mean age of patients was 11.3 +/- 3.8 years. Mean duration of DM was determined as 3.7 +/- 3.1 years. Majority of patients (85.5%) used basal/bolus injection (BBI), and 6.5% used continuous subcutaneous insulin infusion pump. Assessment of glycemic control based on HbA1c levels showed that 29.1% of patients had an HbA1c value <7.5% (58 mmol/mol), 16.1% had a value between 7.5% (58 mmol/mol) and 8% (64 mmol/mol), 19.1% had a value between 8.1% (64 mmol/mol) and 9%(75 mmol/mol) and 35.7% a value >9%(75 mmol/mol). Hypoglycemia was reported in 145 (29.1%) patients and the number of severe hypoglycemic attacks in the last 3 months was 1.0 +/- 2.4. Taking into consideration the carbohydrate count and insulin correction dose and parents with high socioeconomic status was related to have better glycemic control. The most common comorbidities were Hashimoto's thyroiditis/hypothyroidism (6.2%) followed by celiac disease (3.8%), epilepsy(1.2%), and asthma(1.0%). Conclusions: BBI insulin therapy is widely used among pediatric T1DM patients in Turkey. However, despite improvements in treatment facilities and diabetic care, glycemic control is not at a satisfactory level. Therefore, new and comprehensive initiatives require for pediatric T1DM patients with poor glycemic control. Promoting use of carbohydrate count and insulin correction doses may improve the glycemic control of pediatric T1DM in Turkey.en_US
dc.description.sponsorshipSanofien_US
dc.identifier.citationHatun, Ş. vd. (2016). "Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study". Diabetes Research and Clinical Practice, 119, 32-40.en_US
dc.identifier.endpage40tr_TR
dc.identifier.issn0168-8227
dc.identifier.issn1872-8227
dc.identifier.pubmed27423071tr_TR
dc.identifier.scopus2-s2.0-84978764792tr_TR
dc.identifier.startpage32tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.diabres.2016.04.059
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0168822716301759
dc.identifier.urihttp://hdl.handle.net/11452/29857
dc.identifier.volume119tr_TR
dc.identifier.wos000381646900004tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationSanayitr_TR
dc.relation.journalDiabetes Research and Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndocrinology & metabolismen_US
dc.subjectType 1 diabetesen_US
dc.subjectChildrenen_US
dc.subjectTreatmenten_US
dc.subjectGlycemic controlen_US
dc.subjectHbA1cen_US
dc.subjectChildrenen_US
dc.subjectAssociationen_US
dc.subjectPrevalenceen_US
dc.subjectRegionen_US
dc.subjectRisken_US
dc.subject.emtreeInsulinen_US
dc.subject.emtreeInsulin asparten_US
dc.subject.emtreeInsulin detemiren_US
dc.subject.emtreeInsulin glargineen_US
dc.subject.emtreeInsulin lisproen_US
dc.subject.emtreeIsophane insulinen_US
dc.subject.emtreePig insulinen_US
dc.subject.emtreeGlucose blood levelen_US
dc.subject.emtreeGlycosylated hemoglobinen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChilden_US
dc.subject.emtreeClinical evaluationen_US
dc.subject.emtreeComorbidityen_US
dc.subject.emtreeContinuous infusionen_US
dc.subject.emtreeCross-sectional studyen_US
dc.subject.emtreeDisease associationen_US
dc.subject.emtreeDisease durationen_US
dc.subject.emtreeDose responseen_US
dc.subject.emtreeDrug effecten_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGlycemic controlen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInsulin dependent diabetes mellitusen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePrescriptionen_US
dc.subject.emtreeSex ratioen_US
dc.subject.emtreeSingle drug doseen_US
dc.subject.emtreeTreatment planningen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAnalysisen_US
dc.subject.emtreeDiabetes mellitus, type 1en_US
dc.subject.emtreeDisease managementen_US
dc.subject.emtreeGlucose blood levelen_US
dc.subject.emtreeInfanten_US
dc.subject.emtreePreschool childen_US
dc.subject.emtreeTurkeyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshBlood glucoseen_US
dc.subject.meshChilden_US
dc.subject.meshChild, preschoolen_US
dc.subject.meshCross-sectional studiesen_US
dc.subject.meshDiabetes mellitus, type 1en_US
dc.subject.meshDisease managementen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemoglobin A, glycosylateden_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusCeliac Disease; Insulin Dependent Diabetes Mellitus; Patient with Type 1 Diabetesen_US
dc.subject.wosEndocrinology & metabolismen_US
dc.titleEvaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional studyen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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