The concentration of adiponectin in breast milk is related to maternal hormonal and inflammatory status during 6 months of lactation

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dc.contributor.buuauthorÖzarda, Yeşim
dc.contributor.buuauthorGüneş, Yeliz
dc.contributor.buuauthorTuncer, Gül Özlem
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.researcheridAAL-8873-2021tr_TR
dc.contributor.scopusid35741320500tr_TR
dc.contributor.scopusid54913156100tr_TR
dc.contributor.scopusid54910813000tr_TR
dc.date.accessioned2022-02-08T11:27:39Z
dc.date.available2022-02-08T11:27:39Z
dc.date.issued2012-05
dc.description.abstractBackground: Varying concentrations of adiponectin are present in human breast milk. This study aimed to determine the relationship between milk adiponectin concentration and the hormonal and inflammatory status of breast-feeding women. Methods: Blood and breast milk samples were collected from 157 breast-feeding women enrolled at 1-180 post-partum lactation days. The milk and serum adiponectin concentrations were measured by radioimmunoassays. The serum oestradiol, prolactin, thyroxine, triiodothyronine, cortisol and insulin concentrations were measured by the chemiluminescent immunometric method. The leptin, resistin and ghrelin concentrations were measured by the immunometric methods. Results: The milk, but not serum, adiponectin concentration increased during the 180-day lactation period and displayed a positive correlation (r=0.748; p<0.001) to the lactation day. The milk adiponectin concentration was positively correlated to the maternal serum ghrelin concentration (r=0.299; p<0.001) and inversely to the maternal serum oestradiol (r=-0.366; p<0.001), prolactin (r=-0.444; p<0.001), thyroxine (r=-0.355; p<0.001), triiodothyronine (r=-0.291; p<0.001), cortisol (r=-0.537; p<0.001), and C-reactive protein (r=-0.483; p<0.001) concentrations. The milk adiponectin concentration was positively correlated to the milk leptin (r=0.344; p<0.001) and ghrelin (r=0.458; p<0.001) concentrations, and inversely to milk resistin concentration (r=-0.518; p<0.001). The serum adiponectin concentration in breastfed infants was positively correlated (r=0.711; p<0.001) to the adiponectin concentration in the consumed breast milk. Conclusions: The adiponectin concentration in breast milk increases over time during lactation and is affected by the maternal hormonal and inflammatory status.en_US
dc.identifier.citationÖzarda, Y. vd. (2012). "The concentration of adiponectin in breast milk is related to maternal hormonal and inflammatory status during 6 months of lactation". Clinical Chemistry and Laboratory Medicine, 50(5), Special Issue, 911-917.en_US
dc.identifier.endpage917tr_TR
dc.identifier.issn1434-6621
dc.identifier.issn1437-4331
dc.identifier.issue5, Special Issueen_US
dc.identifier.pubmed22628336tr_TR
dc.identifier.scopus2-s2.0-84867827343tr_TR
dc.identifier.startpage911tr_TR
dc.identifier.urihttps://doi.org/10.1515/cclm-2011-0724
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/22628336/
dc.identifier.urihttps://www.degruyter.com/document/doi/10.1515/cclm-2011-0724/html
dc.identifier.urihttp://hdl.handle.net/11452/24377
dc.identifier.volume50tr_TR
dc.identifier.wos000304434200021tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWalter de Gruyter Gmbhen_US
dc.relation.bap2002/34tr_TR
dc.relation.journalClinical Chemistry and Laboratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMedical laboratory technologyen_US
dc.subjectAdiponectinen_US
dc.subjectBreastfed infants milken_US
dc.subjectLactationen_US
dc.subjectSerum cortisolen_US
dc.subjectSerum prolactinen_US
dc.subjectSerum thyroxineen_US
dc.subjectC-reactive proteinen_US
dc.subjectAdipose-tissueen_US
dc.subjectHuman adipocytesen_US
dc.subjectBirth-weighten_US
dc.subjectCord blooden_US
dc.subjectLeptinen_US
dc.subjectSerumen_US
dc.subjectExpressionen_US
dc.subjectGhrelinen_US
dc.subjectAdipokinesen_US
dc.subject.emtreeAdiponectinen_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeEstradiolen_US
dc.subject.emtreeGhrelinen_US
dc.subject.emtreeHydrocortisoneen_US
dc.subject.emtreeLeptinen_US
dc.subject.emtreeLiothyronineen_US
dc.subject.emtreeProlactinen_US
dc.subject.emtreeResistinen_US
dc.subject.emtreeThyroxineen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBlood samplingen_US
dc.subject.emtreeBreast feedingen_US
dc.subject.emtreeBreast milken_US
dc.subject.emtreeChemoluminescenceen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeEstradiol blood levelen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHormone blood levelen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHydrocortisone blood levelen_US
dc.subject.emtreeLactationen_US
dc.subject.emtreeLiothyronine blood levelen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProlactin blood levelen_US
dc.subject.emtreePuerperiumen_US
dc.subject.emtreeRadioimmunoassayen_US
dc.subject.emtreeThyroxine blood levelen_US
dc.subject.meshAdiponectinen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBiological markersen_US
dc.subject.meshC-reactive proteinen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInflammationen_US
dc.subject.meshLactationen_US
dc.subject.meshMilk, humanen_US
dc.subject.meshMothersen_US
dc.subject.meshReproductionen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusHuman Milk; Leptin; Adiponectinen_US
dc.subject.wosMedical laboratory technologyen_US
dc.titleThe concentration of adiponectin in breast milk is related to maternal hormonal and inflammatory status during 6 months of lactationen_US
dc.typeArticle
dc.wos.quartileQ1en_US

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