Active and total ghrelin concentrations increase in breast milk during lactation

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dc.contributor.buuauthorİlçöl, Yeşim Özarda
dc.contributor.buuauthorHızlı, Banu
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.researcheridAAL-8873-2021tr_TR
dc.contributor.scopusid35741320500tr_TR
dc.contributor.scopusid14019332100tr_TR
dc.date.accessioned2022-09-07T13:43:37Z
dc.date.available2022-09-07T13:43:37Z
dc.date.issued2007-11
dc.description.abstractAim: To assess ghrelin status in breast milk and maternal serum for up to 180 days during lactation and to determine relationships between the concentrations of ghrelin in mother's milk and in serum of breastfed infants. Methods: Blood and breast milk samples were collected from 159 breastfeeding women enrolled either in the first 3 days, or in days 4-14, 15-30, 31-90 and 91-180 postpartum. Blood samples were also collected from 49 breastfed infants at 4-30 days of age. Milk and serum active and total ghrelin concentrations were measured by radioimmunoassay. Results: Active and total ghrelin concentrations in breast milk were lowest (450 ± 25 and 880 ± 80 pg/mL, respectively) at 0-3 days, whereas they increased progressively during 180 days of lactation period to 801 ± 43 and 3250 ± 380 pg/mL at 91-180 days postpartum. Milk total ghrelin concentrations correlated with serum concentrations of active (r = 0.503; p < 0.001) and total ghrelin (r = 0.331; p < 0.05) in breastfed infants at 4-30 days of age. In breastfeeding women, serum total ghrelin concentrations increased whereas serum active ghrelin concentrations decreased significantly during the next 4-180 days. Conclusion: Active and total ghrelin concentrations in breast milk increase with time during lactation and show significant relations with serum ghrelin concentrations in breastfed infants.en_US
dc.identifier.citationİlçöz, Y. Ö. ve Hızlı, B. (2007). "Active and total ghrelin concentrations increase in breast milk during lactation". Acta Paediatrica, 96(1), 1632-1639.en_US
dc.identifier.endpage1639tr_TR
dc.identifier.issn16512227
dc.identifier.issue11tr_TR
dc.identifier.pubmed17888057tr_TR
dc.identifier.scopus2-s2.0-35348969799tr_TR
dc.identifier.startpage1632tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1651-2227.2007.00493.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1651-2227.2007.00493.x
dc.identifier.urihttp://hdl.handle.net/11452/28548
dc.identifier.volume96tr_TR
dc.identifier.wos000250261500015tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalActa Paediatricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectActive ghrelinen_US
dc.subjectBreast milken_US
dc.subjectLactationen_US
dc.subjectTotal ghrelinen_US
dc.subjectDes-octanoyl ghrelinen_US
dc.subjectBiochemical-propertiesen_US
dc.subjectAcyl ghrelinen_US
dc.subjectSecretionen_US
dc.subjectInfantsen_US
dc.subjectPeptideen_US
dc.subjectTermen_US
dc.subjectRaten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeRadioimmunoassayen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeBreast feedingen_US
dc.subject.emtreeBlood samplingen_US
dc.subject.emtreeBreast milken_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLactationen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreePuerperiumen_US
dc.subject.meshAdulten_US
dc.subject.meshAnalysis of varianceen_US
dc.subject.meshLongitudinal studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshRadioimmunoassayen_US
dc.subject.meshCross-sectional studiesen_US
dc.subject.meshGhrelinen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, newbornen_US
dc.subject.meshLactationen_US
dc.subject.meshMilk, humanen_US
dc.subject.meshTime factorsen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusGhrelin Receptors; Acyltransferases; Eatingen_US
dc.subject.wosPediatricsen_US
dc.titleActive and total ghrelin concentrations increase in breast milk during lactationen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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