50 yaş ve üzeri kadınlarda D vitamini ve probiyotik takviye edilmiş yoğurdun günlük tüketiminin yaşam kalitesi, depresyon, antropometrik ölçümler ve bazı kan parametreleri üzerine etkisi
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Date
2019-12-24
Authors
Küçük, Sefa Can
Journal Title
Journal ISSN
Volume Title
Publisher
Bursa Uludağ Üniversitesi
Abstract
Bu çalışmada, D vitamini eksikliği/yetersizliği olan 50 yaş ve üzeri kadınlarda D vitamini ve probiyotik takviye edilmiş yoğurdun günlük tüketiminin yaşam kalitesi, depresyon, antropometrik ölçümler ve bazı kan parametreleri üzerine etkisinin araştırılması amaçlandı. Bu çalışmada, Mart- Mayıs 2019 tarihleri arasında Bursa'da bir hobi kursuna giden 50 yaş ve üzeri kadınlar üç ayrı durumda ziyaret edildi. İlk ziyarette kan örnekleri alındı ve serum 25(OH)D düzeyi 30 ng/mL'den düşük olan 150 kadın ile çalışmaya devam edildi. Ardından, genel özellikler, yaşam kalitesi ve depresyon ile ilgili anketler tamamlandı. Antropometrik ölçümler ise standartlara uygun şekilde ölçüldü. Daha sonra; kontrol grubu (Grup 1), yoğurt tüketen grup (Grup 2), yoğurt ile birlikte 5x109 kob/g probiyotik takviyesi alan grup (Grup 3), yoğurt ile birlikte D vitamini alan grup (Grup 4), yoğurt ile birlikte D vitamini ve probiyotik takviyesi alan grup olmak üzere beş farklı çalışma grubu oluşturuldu. Çalışmanın 12. haftasındaki üçüncü ziyarette tekrar kan örnekleri alındı ve birinci ziyarette uygulanan anketler ve ölçümler tekrar gerçekleştirildi. Kadınların %21,3'ünde D vitamini yetersizliği, %78,7'sinde ise D vitamini eksikliği vardı. Tüm gruplar arasındaki başlangıç antropometrik ölçümler, kan bulguları, yaşam kalitesi ve depresyon skorları açısından anlamlı bir farklılık saptanmadı (p>0,05). Grup 1, Grup 2, Grup 3 ve Grup 4'teki kadınlara kıyasla Grup 5'teki kadınların vücut ağırlıkları ortalamalarının daha fazla azaldığı, serum 25(OH)D seviyelerinin daha fazla yükseldiği ve depresyon skorlarının daha fazla iyileştiği tespit edildi (p<0,05). Ayrıca, Grup 5'teki kadınların diğer gruplardan farklı olarak yaşam kalitesi ölçeğinin tüm alt parametre skorlarının arttığı tespit edildi (p<0,05). D vitamini takviyesine karşılık, D vitamini ile birlikte probiyotik takviyesinin vücut ağırlığını daha fazla azalttığı; serum 25(OH)D seviyesini daha fazla yükselttiği; yaşam kalitesi ve depresyon üzerine ise daha olumlu etki gösterdiği sonucuna ulaşıldı.
Aim: The aim of this study was to investigate the effect daily consumption of vitamin D and probiotic supplemented yogurt on quality of life, depression, anthropometric measurements and some blood parameters in women aged 50 years and older with vitamin D deficiency/insufficiency. Materials and In this study, women aged 50 years and over who attended a hobby course in Bursa between March and May 2019 were visited in three different situations. Blood samples were collected at the first visit and the study was continued with 150 women with a serum 25(OH)D level of less than 30 ng/mL. Then, questionnaires about general characteristics, quality of life and depression were completed. Anthropometric measurements were measured in accordance with the standards. Later; control group (Group 1), yogurt consuming group (Group 2), yogurt with 5x109 CFU/g probiotic supplement group (Group 3), yogurt with vitamin D group (Group 4), yogurt with vitamin D and probiotic supplement group to be five different working groups were formed. Blood samples were taken again at the third visit in the 12th week of the study and the questionnaires and measurements were performed again at the first visit. Vitamin D insufficiency was found in 21,3% of the women and vitamin D deficiency was found in 78,7% of the women. There was no significant difference between the groups in terms of baseline anthropometric measurements, blood findings, quality of life and depression scores (p>0,05). Compared to the women in Group 1, Group 2, Group 3 and Group 4, it was found that women in Group 5 decreased more the average body weight, higher serum 25(OH)D levels, and depression scores were improved (p<0,05). In addition, it was found that all sub-parameter scores of the quality of life scale of the women in Group 5 were higher than the other groups (p<0,05). Conclusion: In contrast to vitamin D supplementation, probiotic supplementation with vitamin D decreased body weight more; further increases serum 25(OH)D level; and it had a more positive effect on quality of life and depression.
Aim: The aim of this study was to investigate the effect daily consumption of vitamin D and probiotic supplemented yogurt on quality of life, depression, anthropometric measurements and some blood parameters in women aged 50 years and older with vitamin D deficiency/insufficiency. Materials and In this study, women aged 50 years and over who attended a hobby course in Bursa between March and May 2019 were visited in three different situations. Blood samples were collected at the first visit and the study was continued with 150 women with a serum 25(OH)D level of less than 30 ng/mL. Then, questionnaires about general characteristics, quality of life and depression were completed. Anthropometric measurements were measured in accordance with the standards. Later; control group (Group 1), yogurt consuming group (Group 2), yogurt with 5x109 CFU/g probiotic supplement group (Group 3), yogurt with vitamin D group (Group 4), yogurt with vitamin D and probiotic supplement group to be five different working groups were formed. Blood samples were taken again at the third visit in the 12th week of the study and the questionnaires and measurements were performed again at the first visit. Vitamin D insufficiency was found in 21,3% of the women and vitamin D deficiency was found in 78,7% of the women. There was no significant difference between the groups in terms of baseline anthropometric measurements, blood findings, quality of life and depression scores (p>0,05). Compared to the women in Group 1, Group 2, Group 3 and Group 4, it was found that women in Group 5 decreased more the average body weight, higher serum 25(OH)D levels, and depression scores were improved (p<0,05). In addition, it was found that all sub-parameter scores of the quality of life scale of the women in Group 5 were higher than the other groups (p<0,05). Conclusion: In contrast to vitamin D supplementation, probiotic supplementation with vitamin D decreased body weight more; further increases serum 25(OH)D level; and it had a more positive effect on quality of life and depression.
Description
Keywords
D Vitamini, Probiyotik, Vitamin D, Probiotic, Food fortification
Citation
Küçük, S.C. (2019). 50 yaş ve üzeri kadınlarda D vitamini ve probiyotik takviye edilmiş yoğurdun günlük tüketiminin yaşam kalitesi, depresyon, antropometrik ölçümler ve bazı kan parametreleri üzerine etkisi. Yayınlanmamış yüksek lisans tezi. Bursa Uludağ Üniversitesi Sağlık Bilimleri Enstitüsü.