Clinical course of hyperprolactinemia in children and adolescents: A review of 21 cases

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dc.contributor.buuauthorEren, Erdal
dc.contributor.buuauthorYapıcı, Senay
dc.contributor.buuauthorÇakır, Esra Deniz Papatya
dc.contributor.buuauthorCeylan, Latife Aytekin
dc.contributor.buuauthorSaǧlam, Halil
dc.contributor.buuauthorTarım, Ömer Faruk
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatrik Endokrinoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalıtr_TR
dc.contributor.orcid0000-0003-0710-5422tr_TR
dc.contributor.orcid0000-0002-1684-1053tr_TR
dc.contributor.researcheridC-7392-2019tr_TR
dc.contributor.researcheridAAH-1155-2021tr_TR
dc.contributor.researcheridAAM-1734-2020tr_TR
dc.contributor.scopusid36113153400tr_TR
dc.contributor.scopusid44161566600tr_TR
dc.contributor.scopusid37003613900tr_TR
dc.contributor.scopusid40461059700tr_TR
dc.contributor.scopusid35612700100tr_TR
dc.contributor.scopusid6701427186tr_TR
dc.date.accessioned2021-12-13T13:34:16Z
dc.date.available2021-12-13T13:34:16Z
dc.date.issued2011-06
dc.description.abstractObjective: Hyperprolactinemia may be due to various etiological factors and may present with different signs and symptoms. It is relatively less frequent in childhood than in adulthood. The aim of this study was to evaluate retrospectively the clinical course and outcome of hyperprolactinemia in pediatric patients. Methods: We investigated the records of 21 patients with hyperprolactinemia who attended a tertiary hospital. Results: Menstrual problems, galactorrhea, and headache were the most common presenting symptoms. Hyperprolactinemia was due to microadenoma in 10, macroadenoma in 7, and was drug-induced in 4 patients. Bromocriptine and cabergoline were equally effective in lowering serum prolactin levels. Surgical treatment in children with macroprolactinoma was not curative and dopamine agonist therapy was required postoperatively. Conclusion: In the presence of any clinical symptom or sign suggestive of suppression of the pituitary-gonadal axis, hyperprolactinemia should not be forgotten as a probable diagnosis. Medical therapy seems effective in microadenoma. Surgical therapy may not be successful in macroadenoma and recurrence is frequent.en_US
dc.identifier.citationEren, E. vd. (2011). "Clinical course of hyperprolactinemia in children and adolescents: A review of 21 cases". Journal of Clinical Research in Pediatric Endocrinology, 3(2), 65-69.en_US
dc.identifier.endpage69tr_TR
dc.identifier.issn1308-5727
dc.identifier.issn1308-5735
dc.identifier.issue2tr_TR
dc.identifier.pubmed21750634tr_TR
dc.identifier.scopus2-s2.0-79959224580tr_TR
dc.identifier.startpage65tr_TR
dc.identifier.urihttps://doi.org/10.4274/jcrpe.v3i2.14
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119443/
dc.identifier.urihttp://hdl.handle.net/11452/23218
dc.identifier.volume3tr_TR
dc.identifier.wos000497376200005tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.indexed.wosBKCISen_US
dc.language.isoenen_US
dc.publisherGalenos Yayıncılıktr_TR
dc.relation.journalJournal of Clinical Research in Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndocrinology & metabolismen_US
dc.subjectPediatricsen_US
dc.subjectProlactinen_US
dc.subjectPubertyen_US
dc.subjectProlactinomaen_US
dc.subjectPituitaryen_US
dc.subject.emtreeBromocriptineen_US
dc.subject.emtreeBromocriptine mesilateen_US
dc.subject.emtreeCabergolineen_US
dc.subject.emtreeDopamine receptor stimulating agenten_US
dc.subject.emtreeProlactinen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeChilden_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeDisease courseen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGalactorrheaen_US
dc.subject.emtreeHeadacheen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHyperprolactinemiaen_US
dc.subject.emtreeHypophysis gonad systemen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMenstruation disorderen_US
dc.subject.emtreeMicroadenomaen_US
dc.subject.emtreePostoperative perioden_US
dc.subject.emtreeProlactinomaen_US
dc.subject.emtreeRecurrence risken_US
dc.subject.emtreeRetrospective studyen_US
dc.subject.emtreeReviewen_US
dc.subject.emtreeSymptomen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshDopamine agonistsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperprolactinemiaen_US
dc.subject.meshMaleen_US
dc.subject.meshPituitary neoplasmsen_US
dc.subject.meshProlactinen_US
dc.subject.meshProlactinomaen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusProlactinoma; Cabergoline; Dopamine Receptor Stimulating Agenten_US
dc.subject.wosEndocrinology & metabolismen_US
dc.subject.wosPediatricsen_US
dc.titleClinical course of hyperprolactinemia in children and adolescents: A review of 21 casesen_US
dc.typeReview
dc.typeBook Chapter

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