Arterial elasticity measurement in patients with Behcet's disease

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dc.contributor.authorUçar, Hakan
dc.contributor.authorYetgin, Zeynel Abidin
dc.contributor.authorAktürk, Yusuf
dc.contributor.authorKaraağaç, Esra Uğurlu
dc.contributor.authorKaraağaç, Kemaltr_TR
dc.contributor.buuauthorSerdar, Osman Akın
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAF-5116-2019tr_TR
dc.contributor.scopusid6507416315tr_TR
dc.contributor.scopusid6603722836tr_TR
dc.date.accessioned2022-02-15T07:43:06Z
dc.date.available2022-02-15T07:43:06Z
dc.date.issued2012
dc.description.abstractBehcet's syndrome is a chronic, multisystem disorder characterized by recurrent oral and genital ulceration, skin lesions and uveitis. In addition, 25% of patients develop vascular complications, which may include superficial thrombophlebitis, deep vein and arterial thrombosis and arterial aneurysm formation. Pulse wave velocity (PWV) is an important factor in determining cardiovascular mortality and morbidity. It is an index of arterial wall stiffness and inversely related to the arterial distensibility. In this study we investigated the arterial distensibility in Behcet's Disease (BD) by PWV. We studied 50 patients with BD and 20 healthy subjects without known cardiovascular disease. Arterial distensibility was assessed by All patients underwent pulse wave analysis (HDI/Pulse Wave model CR-2000) to determine large and small vessel compliances. Large arterial elastisite index (LAEI) and small arterial elastisite index (SAEI) of the radial artery were determined from an internal algorhythm based on diastolic decay features of the calibrated radial pulse contour using a modified Windkessel model. The mean ages, systolic blood pressure, diastolic blood pressure, large arterial elastisite index (LAE), small arterial elastisite index (SAE) of Behcet's disease and control subjects were 37 +/- 8.323 and 37 +/- 7.984 years, 125,8 +/- 3 and 124,3 +/- 11.4 mmHg, 68.5 +/- 7.7 and 68.5 +/- 7.7 mmHg, 13.3 +/- 3.6 and 13.6 +/- 3.64 mL/mm Hg X 10, 5.2 +/- 2.43 and 6.01 +/- 2.6 mL/mm Hg X 100 respectively. Differences between all parameters studied were not found to be statistically significant (p > 0.05). Furthermore, in patients group there were no significant correlation between disease duration and LAEI(C1) and SAEI(C2) (p=0.267 and p=0.456, respectively). Eventually, no significant correlation was shown between increase in systemic involvement, LAEI and SAEI values (p=0.447 and p=0.345, respectively). In this study, it was shown that Behcet's disease did not change arterial stiffness parameters used as a strong indicator of atherosclerosis. Further, it was determined that disease duration and increase in systemic involvement did not alter arterial stiffness parameters.en_US
dc.identifier.citationUçar, H. vd. (2012). "Arterial elasticity measurement in patients with Behcet's disease". Healthmed, 6(10), 3255-3260.en_US
dc.identifier.endpage3260tr_TR
dc.identifier.issn1840-2291
dc.identifier.issue10tr_TR
dc.identifier.scopus2-s2.0-84871245874tr_TR
dc.identifier.startpage3255tr_TR
dc.identifier.urihttps://hero.epa.gov/hero/index.cfm/reference/details/reference_id/1570758
dc.identifier.urihttp://hdl.handle.net/11452/24473
dc.identifier.volume6tr_TR
dc.identifier.wos000312158300003tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.collaborationSanayitr_TR
dc.relation.journalHealthmeden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGeneral & internal medicineen_US
dc.subjectBehcet diseaseen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectArterial stiffnessen_US
dc.subjectVascular endothelial functionen_US
dc.subjectIntima-media thicknessen_US
dc.subjectPulse-wave velocityen_US
dc.subjectIn-vivoen_US
dc.subjectNitric-oxideen_US
dc.subjectDependent dilatationen_US
dc.subjectSystemic vasculitisen_US
dc.subjectStiffnessen_US
dc.subjectInflammationen_US
dc.subjectDistensibilityen_US
dc.subject.emtreeColchicineen_US
dc.subject.emtreeCorticosteroiden_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeen_US
dc.subject.emtreeArterial stiffnessen_US
dc.subject.emtreeArtery complianceen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBehcet diseaseen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeClinical featureen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDiastolic blood pressureen_US
dc.subject.emtreeDisease durationen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeImmunosuppressive treatmenten_US
dc.subject.emtreeLarge arterial elastisite indexen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePulse waveen_US
dc.subject.emtreeSmall arterial elastisite indexen_US
dc.subject.emtreeSystolic blood pressureen_US
dc.subject.scopusBehcet Syndrome; False Aneurysm; Systemic Vasculitisen_US
dc.subject.wosMedicine, general & internalen_US
dc.titleArterial elasticity measurement in patients with Behcet's diseaseen_US
dc.typeArticle

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