A new Synthesis of n-substituted-1,2,3,4-tetrahydro-4-phenylisoquinolin-3-ones
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Date
1993
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Marcel Dekker Inc
Abstract
1,2,3,4-Tetrahydro-4-phenylisoquinolin-3-ones 3 are obtained from appropriate N,N-disubstituted phenylacetamides 1, using lead tetraacetate ( LTA ) as oxidant and Lewis or proton acids as cyclizing agents. The methods for this conversion could be one stage ( method B or C ), or two stages ( method A ). The latter method was particularly developed to explain the mechanism of the reaction.
Description
Keywords
Chemistry, 4-Aryl, Tetrahydroisoquinolines, Disubstituted
Citation
Coşkun, N. ve Sümengen, D. (1993). ''A New Synthesis of N-Substituted-1,2,3,4-tetrahydro-4-phenylisoquinolin-3-ones''. Synthetic Communications, 23(10), 1393-1402.