2024-02-222024-02-222014-01Gurbet, A. vd. (2014). "Preemptive wound infiltration in lumbar laminectomy for postoperative pain: comparison of bupivacaine and levobupivacaine". Türk Beyin Cerrahisi, 24(1), 48-53.1019-5149https://hdl.handle.net/11452/39897AIM: Patients usually suffer significant pain after lumbar laminectomy. Wound infiltration with local anesthetics is a useful method for postoperative pain control. Our aim was to compare the efficacies of preemptive wound infiltration with bupivacaine and levobupivacaine. MATERIAL and METHODS: 60 patients were randomized three groups as follows: Group L wound infiltration with 20 mL 0.25% levobupivacaine and 40 mg methylprednisolone just before wound closure; Group B wound infiltration with 20 mL 0.25% bupivacaine and 40 mg methylprednisolone before closure; Group C had this region infiltrated with 20 ml physiological saline. Demographic data, vital signs, postoperative pain scores and morphine usage were recorded. RESULTS: First analgesic requirement time was significantly shorter in the control group compared to other two groups (p<0.001). Group B had the lowest cumulative morphine consumption at the end of 24 hours within 0-4, 4-12 and 12-24 hours time intervals and the values were not significant when compared with Group L, however the consumption of both groups was significantly lower compared to the control group (p<0.001). CONCLUSION: Our data suggest that preoperative infiltration of the wound site with bupivacaine or levobupivacaine provides similarly effective pain control with reduced opiate dose after unilateral lumbar laminectomy.eninfo:eu-repo/semantics/closedAccessBupivacainePostoperative painLevobupivacaineLumbar laminectomyPulmonary complicationsSurgeryPerioperative useMorphineAnalgesiaDiseaseDiskectomyAnesthesiaTrialNeurosciences & neurologySurgeryAdolescentAdrenal cortex hormonesAdultAgedAnalgesics, opioidAnesthetics, localBlood pressureBupivacaineDouble-blind methodFemaleHeart rateHumansIntervertebral discLaminectomyLumbar vertebraeMaleMethylprednisoloneMiddle agedMorphinePain measurementPain, postoperativeYoung adultArticle0003316633000112-s2.0-84894107154485324124535791https://doi.org/10.5137/1019-5149.JTN.8431-13.0Clinical neurologySurgeryPostoperative Pain; Scoliosis; Patient Controlled AnalgesiaAdolescentAdultAgedArticleBlood pressureComparative studyControlled clinical trialControlled studyDouble blind procedureDrug effectFemaleHeart rateHumanIntervertebral diskLaminectomyLumbar vertebraMaleMethodologyMiddle agedPain assessmentPostoperative painRandomized controlled trialYoung adultBupivacaineCorticosteroidDrug derivativeLevobupivacaineLocal anesthetic agentMethylprednisoloneMorphineNarcotic analgesic agent