2022-04-202022-04-202012-04Özdemir, Ö. vd. (2012). "Chronic inflammatory demyelinating polyneuropathy in common variable immunodeficiency". Pediatric Neurology, 46(4), 260-262.0887-89941873-5150https://doi.org/10.1016/j.pediatrneurol.2012.02.009https://www.sciencedirect.com/science/article/pii/S0887899412000562http://hdl.handle.net/11452/25897Common variable immunodeficiency comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunologic phenotypes. Immune dysregulation leads to the generation of multiple autoantibodies against various antigenic targets in patients with common variable immunodeficiency. Chronic inflammatory demyelinating polyneuropathy is a heterogeneous disorder that indicates an autoimmune response against peripheral nerve myelin. We describe a 7-year-old girl with common variable immunodeficiency who developed chronic inflammatory polyneuropathy. A 5-day course of intravenous immunoglobulin (500 mg/kg/day) improved her neurologic disorder. Chronic inflammatory demyelinating polyneuropathy should be added to the broadening spectrum of neurologic complications in common variable immunodeficiency. Early detection and consequent treatment may reverse the neurologic sequelae.eninfo:eu-repo/semantics/closedAccessNeurosciences & neurologyPediatricsDiseaseChildCommon variable immunodeficiencyFemaleHumansNeural conductionPeripheral nervesPolyradiculoneuropathy, chronic inflammatory demyelinatingArticle0003032220000132-s2.0-8485953082726026246422490776Clinical neurologyPediatricsCommon Variable Immunodeficiency; Immunoglobulin Deficiency; ImmunosuppressionAciclovirBrain proteinCd4 antigenCd8 antigenImmunoglobulinImmunoglobulin aImmunoglobulin gImmunoglobulin mAchilles reflexAntibody responseArticleCase reportCd8+ t lymphocyteChildChronic inflammatory demyelinating polyneuropathyCommon variable immunodeficiencyDiarrheaElectromyographyFemaleHelper cellHerpes zosterHumanImmunoassayImmunoglobulin blood levelImmunotherapyLimb weaknessLung infectionLymphocyte countLymphocyte proliferationMedian nerveMotor nerve conductionNatural killer cellNerve conductionNeurologic examinationPriority journalQuadriplegiaRecurrent infectionSchool childTibial nerveTreatment responseUlnar nerveWalking difficulty