Güvenç, OrhanEngin, M.2024-09-252024-09-252023-01-011128-3602https://hdl.handle.net/11452/45262OBJECTIVE: Acute Type A aortic dissection (ATAAD) is an emergency cardiovascular condition. In this current study, we aimed to investigate the prognostic importance of pre-operative neutrophil-lymphocyte platelet ratio (NLPR) value in predicting in-hospital mortality, after surgical treatment of ATAAD.PATIENTS AND METHODS: Consecutive patients who underwent an emergency operation as a result of ATAAD between August 2012 and August 2021 in our hospital, were retrospectively included in this study. Patients who survived the operation and were released were recorded as Group 1 and those who died in the hospital, as Group 2.RESULTS: Mortality (in-hospital) occurred in 44 (22.5%) patients (Group 2). The median age of the 151 patients included in Group 1 and 44 patients in Group 2 were 55 (37 to 81) and 59 (33 to 72) years, respectively (p = 0.191). In multivariate analysis Model 1, malperfusion (OR: 3.764, 95% CI: 2.140-4.152, p < 0.001), total perfusion time (OR: 1.156, 95% CI: 1.040-1.469, p = 0.012), low plate-let counts (OR: 0.894, 95% CI: 0.685-0.954, p = 0.035) and NLR (OR: 1.944, 95% CI: 1.230-2.390, p < 0.001) were determined as independent predictors for mortality. In Model 2, malperfusion (OR: 3.391, 95% CI: 2.426-3.965, p < 0.001) and NLPR (OR: 2.371, 95% CI: 1.892-3.519, p < 0.001) were determined as independent predictors for mortality.CONCLUSIONS: According to our study, the NLPR value obtained preoperatively can be used to predict the risk of in-hospital mortality, after ATAAD surgery.eninfo:eu-repo/semantics/closedAccessC-reactive proteinCountsRiskEventsInjuryAortic dissectionInflammationNeutrophilsPlate-letsMortalityScience & technologyLife sciences & biomedicinePharmacology & pharmacyArticle00100603730001115341539274