2022-11-072022-11-072011Karkucak, M. vd. (2011). "Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report". UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, 21(3), 192-195.1306-133Xhttps://doi.org/10.4999/uhod.09122http://www.uhod.org/pdf/PDF_479.pdfhttp://hdl.handle.net/11452/29422Fluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL). Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Near-tetraploidy. Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.Pre- B Akut Lenfoblastik Lösemi tanısı konulan 11 yaşında erkek olguda, Floresans insitu hibridizasyon analizinde t(12;21)(p13;q22) translokasyonu ve near-tetraploidi beraber olduğu gösterilmiştir. Bazı çalışmalarda t(12;21)(p13;q22) trans lokasyonunun iyi prognostik etki oluşturduğu belirtmelerine rağmen near-tetraploidinin prognostik etkisi hakkında çok az bil gi vardır. Burada Pre-B Akut Lenfoblastik Lösemili olguda t(12;21)(p13;q22) translokasyonu ile birlikte near tetraplodi bulgu larının birlikte etkisi tartışılmaktadır.eninfo:eu-repo/semantics/openAccessOncologyChildhood acute lymphoblastic leukemiaNear-tetraploidyT(12;21)MoleculageneticsHyperdiploidyTel-aml1ChildrenÇocukluk çağı akut lenfoblastik lösemiNear-Tetraplodi, t(12;21)Article0002955732000112-s2.0-80053646851192195213OncologyAcute Lymphoblastic Leukemia; Chromosome 21; Pre B LymphocyteAntineoplastic agent EMTREE medical termsAcute lymphoblastic leukemiaArticleCase reportChildChildhood leukemiaChromosome 13pChromosome translocation 12CytogeneticsFluorescence in situ hybridizationFollow upHumanLaboratory testMalePrognosisRelapseSchool childTetraploidyTreatment response