2024-02-062024-02-062013-10-11Sarkut, P. T. vd. (2013). "Early graft dysfunction and mortality rate in marginal donor liver transplantation". Turkish Journal of Medical Sciences, 44(4), 709-711.1300-01441303-6165https://doi.org/10.3906/sag-1306-123https://journals.tubitak.gov.tr/medical/vol44/iss4/30/https://hdl.handle.net/11452/39532Background/aim: To determine the effect of marginal donor livers on mortality and graft survival in liver transplantation (LT) recipients. Materials and methods: Donors with any 1 of following were considered marginal donors: age >= 65 years, sodium level >= 165 mmol/L and cold ischemia time >= 12 h. Donors were classified according to the donor risk index (DRI) <1.7 and >= 1.7. The transplant recipients' model for end-stage liver disease (MELD) scores were considered low if <20 and high if >= 20. Early graft dysfunction (EGD) and mortality rate were evaluated. Results: During the study period 47 patients underwent cadaveric LT. The mean age of the donors and recipients was 45 years (range: 5-72 years) and 46 years (range: 4-66 years), respectively. In all, there were 15 marginal donors and 18 donors with a DRI > 1.7. In total, 4 LT patients that received livers from marginal donors and 5 that received livers from donors with a DRI >= 1.7 had EGD. Among the recipients of marginal livers, 5 died, versus 4 of the recipients of standard livers. There was no significant difference in EGD or mortality rate between the patients that received livers from marginal donors or those with a DRI = 1.7 and patients that received standard donor livers. Conclusion: Marginal and DRI >= 1.7 donors negatively affected LT outcomes, but not significantly.eninfo:eu-repo/semantics/openAccessCadaveric liver transplantationMortalityEarly graft dysfunctionMarginal donorRisk indexModelRecipientFailureSurvivalGeneral & internal medicineAdolescentAdultAge factorsAgedCadaverChildChild, preschoolCold ischemiaEnd stage liver diseaseFemaleGraft survivalHumansLiver transplantationMaleMiddle agedRetrospective studiesRisk factorsTissue donorsTreatment outcomeYoung adultArticle0003369591000302-s2.0-8490107145870971144425551947Medicine, general & internalLiver Transplantation; Tissue Donors; Graft SurvivalAdolescentAdultArticleChildCold ischemiaDonor risk indexGraft dysfunctionHumanLiver transplantationMajor clinical studyModel for end stage liver disease scoreMortalityRetrospective studyScoring systemAgeAgedCadaverDonorEnd stage liver diseaseFemaleGraft survivalMaleMiddle agedPreschool childRisk factorTreatment outcomeYoung adult