2021-12-082021-12-082009-10Algın, O. vd. (2009). "Evaluation of sacroiliitis: Contrast-enhanced MRI with subtraction technique". Skeletal Radiology, 38(10), 983-988.0364-2348https://doi.org/10.1007/s00256-009-0723-9https://link.springer.com/article/10.1007%2Fs00256-009-0723-9http://hdl.handle.net/11452/23059The purpose of the study was to investigate the diagnostic value of contrast-enhanced MRI using the subtraction technique in the detection of active sacroiliitis. Magnetic resonance imaging was performed in 8 asymptomatic volunteers and 50 patients with clinically suspected active sacroiliitis. On precontrast MR images, T1-weighted spin-echo images with and without fat saturation (T1WFS and T1W), STIR and 3D-FLASH images with fat saturation were obtained in the semicoronal plane using a 1.5 Tesla imager. Postcontrast MRI was performed using the same T1WFS sequence as before contrast injection for all volunteers and patients. Postcontrast images were subtracted from fat-suppressed precontrast images. Enhancement within the joint space and bone marrow was considered to demonstrate active sacroiliitis. In 50 patients (100 sacroiliac joints [SIJs]), 40 (76 SIJs) were considered to have active sacroiliitis based on MR images. Bone marrow edema was present in 33 patients (62 SIJs) on STIR images. Routine MRI allowed identification of contrast enhancement in SIJs on postcontrast T1WFS images in 31 patients (49 SIJs). Contrast enhancement was observed in 40 patients (76 SIJs) who were examined by MRI using the subtraction technique. Contrast enhancement was significantly more conspicuous on subtraction images than on non-subtracted postcontrast T1WFS images (Mann-Whitney U test, paEuro dagger < aEuro dagger 0.001). Contrast-enhanced MRI with subtraction technique may be useful for early detection of active sacroiliitis.eninfo:eu-repo/semantics/closedAccessMagnetic resonance imagingMRISacroiliac jointSacroiliitisSubtraction techniqueEarly seronegative spondylarthropathyAnkylosing-spondylitisRadiographyAbnormalitiesJointsCtOrthopedicsRadiology, nuclear medicine & medical imagingArticle0002693785000062-s2.0-69549121827983988381019506864OrthopedicsRadiology, nuclear medicine & medical imagingAnkylosing Spondylitis; Sacroiliac Joint; SpondylarthropathiesGadolinium pentetateGadolinium pentetate meglumineAdultArticleBone marrowClinical articleContrast enhancementControlled studyDiagnostic valueEarly diagnosisFemaleHumanImage subtractionMaleNuclear magnetic resonance imagingPriority journalRank sum testSacroiliac jointSacroiliitisThree dimensional imaging