2022-12-192022-12-192016-07-20Atalay, M. A. vd. (2016). "Change in the ovarian environment after hysterectomy with bilateral salpingectomy: Is it the technique or surgery itself?". European Journal of Obstetrics and Gynecology and Reproductive Biology, 204, 57-61.0301-21151872-7654https://doi.org/10.1016/j.ejogrb.2016.07.483https://www.sciencedirect.com/science/article/pii/S0301211516308089http://hdl.handle.net/11452/29949Objective: To compare the effects of total laparoscopic hysterectomy with bilateral salpingectomy (TLH-BS) and total abdominal hysterectomy with bilateral salpingectomy (TAH-BS) on ovarian function among women of reproductive age. Study design: One hundred and three patients with a diagnosis of benign uterine disorder were divided into two groups in this prospective longitudinal study. Patients who had never had sexual intercourse and patients with uterovaginal disproportion underwent TAH-BS (n = 57), and the remaining patients (n = 46) underwent TLH-BS. Ovarian function was assessed before and 6 months after surgery; ovarian volume was assessed by gray-scale ultrasonography, and levels of serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), oestradiol (E2), anti-Mullerian hormone (AMH) and inhibin B were measured. Results: Postoperative serum FSH, LH and inhibin B decreased significantly in both groups. Postoperative serum E2 did not change significantly. Postoperative serum AMH and ovarian volume decreased significantly in the TAH-BS group (p = 0.016 and p < 0.001, respectively), but not in the TLH-BS group. Significant differences were observed between the TLH-BS and TAH-BS groups with respect to change in FSH (p = 0.012) and ovarian volume (p = 0.001); between-group differences were not significant for changes in AMH and inhibin B. Conclusions: Although serum AMH did not change significantly in patients who underwent TLH-BS, ovarian aging commenced following both surgical procedures.eninfo:eu-repo/semantics/closedAccessObstetrics & gynecologyReproductive biologyAbdominal hysterectomyLaparoscopic hysterectomySalpingectomyAnti-mullerian hormoneOvarian functionAnti-mullerian hormoneTotal abdominal hysterectomyReserveFshWomenPreservationMenopauseEstradiolInhibinsLevelAdultAnti-mullerian hormoneEstradiolFemaleFollicle stimulating hormoneHumansHysterectomyInhibinsLuteinizing hormoneMiddle agedOrgan sizeOvaryPostoperative periodSalpingectomyUterine diseasesArticle0003853219000112-s2.0-84981306461576120427522244Obstetrics & gynecologyReproductive biologyOvarian Neoplasms; Fallopian Tubes; Carcinoma In SituEstradiolFollitropinInhibin BLuteinizing hormoneMuellerian inhibiting factorEstradiolFollitropinInhibinInhibin BLuteinizing hormoneMuellerian inhibiting factorAbdominal hysterectomyAdultArticleBenign uterus tumorBilateral salpingectomyEstradiol blood levelFemaleFollitropin blood levelGray scale echographyHumanLaparoscopic surgeryLongitudinal studyLuteinizing hormone blood levelMajor clinical studyOutcome assessmentOvary functionPostoperative periodPriority journalProspective studySalpingectomySexual intercourseUterus weightBloodDiagnostic imagingHysterectomyMiddle agedOrgan sizeOvaryPhysiologyUterus disease