2023-01-112023-01-112018-06-04Aydın, S. Z. vd. (2018). ''Axial psoriatic arthritis: the impact of underdiagnosed disease on outcomes in real life''. Clinical Rheumatology, 37(12), 3443-3448.0770-31981434-9949https://doi.org/10.1007/s10067-018-4173-4https://link.springer.com/article/10.1007/s10067-018-4173-4http://hdl.handle.net/11452/30379Çalışmada 25 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.Psoriatic arthritis (PsA) may affect different joints, including the spine. The prevalence of spinal involvement is variable depending on the definition and a subset of patients have been identified in cohorts that do not have clinical features of axial disease and yet have imaging findings. Still, there is not a consensus on how and when to screen axial disease. In this study, we aimed to investigate factors associated with being underdiagnosed for axial psoriatic arthritis (axPsA) and its impacts on outcomes. Disease features and outcomes of axPsA according to the physician (n=415) were compared with patients with imaging findings only (sacroiliitis fulfilling the modified New York criteria, n=112), using data from a real-life PsA registry. Patients with imaging findings only were more frequently women (83/220 (37.7%) vs 29/122 (23.8%); p=0.008). This group also had higher peripheral disease activity (imaging only vs clinical AxPsA: mean (SD) tender joint count 5.3 (6.1) vs 3.3 (4.7), swollen joint count 1.9 (2.9) vs 1.2 (2.4); p<0.001 for both comparisons) and was less often treated using TNF inhibitors (16.1 vs 38.2%; p<0.001) than patients who were classified as axPsA. Patient-reported outcomes were similar in both groups. PsA patients, especially women with more severe peripheral disease, have a higher risk of being underdiagnosed for axPsA. The severity of peripheral symptoms may be a risk factor to mask the spinal features of PsA.eninfo:eu-repo/semantics/closedAccessRheumatologyAxial diseasePsoriatic arthritisRadiographySpondyloarthropathyRecommendationsCriteriaAdultArthritis, psoriaticArthrographyFemaleHumansInflammationMaleMiddle agedPatient reported outcome measuresPrevalenceRadiographyRegistriesReproducibility of resultsRheumatologyRisk factorsSacroiliitisSeverity of illness indexSpineTreatment outcomeTurkeyArticle0004517293000382-s2.0-8504851084434433448371229948352RheumatologyPustulosis Palmoplantaris; Secukinumab; Nail DiseasesTumor necrosis factor inhibitorAdultArticleAssociationAxial psoriatic arthritisCervical spineClinical featureClinical outcomeCohort analysisControlled studyDiagnostic errorDisease activityFemaleHumanJoint radiographyLumbar spineMajor clinical studyMaleModified new york criteriaMusculoskeletal disease assessmentMusculoskeletal system parametersPatient-reported outcomePhysicianPriority journalPsoriatic arthritisReliabilitySacroiliac jointSacroiliitisSex differenceSpine radiographySwollen joint countTender joint countUnderdiagnosisArthrographyComplicationDiagnostic imagingEpidemiologyInflammationMiddle agedPrevalencePsoriatic arthritisRadiographyRegisterReproducibilityRheumatologyRisk factorSeverity of illness indexSpineStandardsTreatment outcomeTurkey (bird)