2022-09-262022-09-262010Topal, A. vd. (2010). "Growth of staphylococcus aureus, Candida albicans, Escherichia coli and Pseudomonas aeruginosa in propofol, thiopental and a 1:1 propofol-thiopental mixture". Journal of Animal and Veterinary Advances, 9(10), 1432-1435.1680-55931993-601Xhttps://doi.org/10.3923/javaa.2010.1432.1435http://www.medwelljournals.com/abstract/?doi=javaa.2010.1432.1435http://hdl.handle.net/11452/28834Extrinsic contamination of propofol is thought to be a source of postoperative sepsis. Researchers studied growth of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans in propofol, thiopental and in a 1:1 propofol-thiopental mixture. All microorganisms were taken from standard stock cultures. Half of the samples were incubated at 20 degrees C and the rest were stored at 4 degrees C for 120 h. Growth of microorganisms in each solution was compared by counting the number of the Colony-Forming Units (CFUs) at 0, 3, 6, 24, 72 and 120 h. Propofol supported the growth of all four microorganims at both temperatures. In contrast, thiopental and the 1:1 propofol-thiopental mixture exhibited markedly bactericidal properties on E. coli, C. albicans and P. aeruginosa and bacteriostatic effect on S. aureus.eninfo:eu-repo/semantics/openAccessIntravenous anestheticsPropofolThiopentalMixtureBacteriaGrowth rateBacterial-contaminationMicroorganismsVeterinary sciencesArticle0002795733000072-s2.0-7795735146814321435910Veterinary sciencesPropofol; Aseptic Conditions; Lidocaine