2022-03-172022-03-172005-04Yıldırım, N. vd. (2005). "Role of diffusion and perfusion-weighted MR imaging in differentiating meningioma from solitary dural metastasis". Rivista di Neuroradiologia, 18(2), 160-168.1120-9976https://doi.org/10.1177/197140090501800204https://journals.sagepub.com/doi/abs/10.1177/197140090501800204http://hdl.handle.net/11452/25109In some instances conventional imaging techniques fall to differentiate meningiomas from isolated dural metastasis. This study aimed to evaluate the role of diffusion and perfusion-weighted MRI in differentiating meningiomas and dural metastasis. In this study, 14 metastasis and 26 meningiomas were involved. The imaging characteristics were analyzed using conventional MRI. Diffusion-weighted MRI was performed and ADC values were calculated from the solid components and the peritumoral edema. Perfusion-weighted MRI was performed and relative cerebral blood volume (rCBV) was calculated. Student's t test was used for the statistical analysis. Dural metastasis and meningiomas could not be differentiated by qualitative assessment of conventional and diffusion-weighted MRI. The mean intratumoral and peritumoral ADC values were not statistically significant (p > 0.05). The rCBV ratios for dural metastasis and meningiomas were 4.13 +/- 2.32 and 7.32 +/- 4.10 respectively and the difference between two was statistically significant (p = 0.003). Peritumoral rCBV ratios for dural metastasis and meningiomas were not statistically significant (p > 0.05). Conventional MRI findings of dural metastasis and meningiomas may overlap in some lesions. In differentiation of these lesions diffusion-weighted MRI yields no further information additional to conventional sequences. Perfusion-weighted MRI can be useful to distinguish these lesions by demonstrating high intratumoral rCBV ratios for meningiomas and low rCBV ratios for metastasis.eninfo:eu-repo/semantics/closedAccessNeurosciences & neurologyRadiology, Nuclear Medicine & Medical ImagingBrainTumorsMeningiomaMetastasisMagnetic resonanceDiffusionPerfusion-weighted imagingUtilityEdemaArticle0002307214000032-s2.0-21844444582160168182NeurosciencesNeuroimagingRadiology, nuclear medicine & medical imagingCerebral Blood Volume; N Acetylaspartic Acid; GlioblastomaGadodiamideAdultAgedArticleBrain blood flowBrain metastasisClinical articleControlled studyDiagnostic imagingDifferential diagnosisDiffusion coefficientDiffusion weighted imagingDura materFemaleHumanImage analysisMaleMeningiomaNeuroimagingPerfusion weighted imagingQualitative analysisStatistical analysis