2024-02-152024-02-152014-06-23Gül, B. C. vd. (2014). "Relationship between glycemic control, microalbuminuria and cognitive functions in elderly type 2 diabetic patients". Renal Failure, 36(8), 1258-1262.0886-022Xhttps://www.tandfonline.com/doi/full/10.3109/0886022X.2014.938576https://hdl.handle.net/11452/39756Aim: The prevalence of diabetes is increasing in elderly populations, and is thought to be an important risk factor for cognitive dysfunction in this age group. Methods: The study included 104 patients aged over 60 years who were followed-up for type 2 diabetes for at least 6 months, in addition to 44 controls. Glycemic parameters, microangiopathic complications, microalbumin elimination, and the Standardized Mini Mental State Examination (SMMSE) scores were used as indicators of cognitive function. Results: The SMMSE scores of diabetic patients were significantly lower than the control group (p<0.05). The average SMMSE score for normoalbuminuric diabetic patients was 22.36 +/- 4.66, compared with 22.61 +/- 4.90 for the microalbuminuria patients (p = 0.84). A positive correlation was found between SMMSE scores and patients' hemoglobin values and education levels, whereas a negative correlation was noted between SMMSE scores and systolic and diastolic blood pressures and hemoglobin A1c levels (p<0.05). Patients with diabetic neuropathy, a microvascular complication of diabetes, were found to have significantly lower SMMSE scores (p = 0.011). Conclusion: Elderly diabetic patients showed decreased cognitive function compared to volunteers. No relationship was established between microalbuminuria and cognitive functions, although diabetic neuropathy was found to be related to decreased cognitive function.eninfo:eu-repo/semantics/openAccessUrology & nephrologyAlbuminuriaCognitive functionsType 2 diabetes mellitusDementiaDiabetic microvascular complicationsStandardized Mini Mental State ExaminationArterial stiffnessOlder-peopleMellitusImpairmentRiskDeclineDysfunctionAlbuminuriaAgedAlbuminuriaBlood glucoseCognition disordersDiabetes mellitus, type 2Diabetic nephropathiesFemaleHumansMaleArticle0003412981000132-s2.0-849066879331258126236825020185https://doi.org/10.3109/0886022X.2014.938576Urology & nephrologyCognitive Dysfunction; Neurofibrillary Tangles; Diabetes MellitusAdultAgedArticleCognitionCognitive defectControlled studyDiabetic neuropathyDiabetic patientDiastolic blood pressureEducational statusFemaleFollow upGlycemic controlHumanMajor clinical studyMaleMicroalbuminuriaMini mental state examinationNon insulin dependent diabetes mellitusPriority journalRisk factorSystolic blood pressureThrombotic thrombocytopenic purpuraAlbuminuriaAnalysisBloodComplicationDiabetic nephropathyGlucose blood levelNon insulin dependent diabetes mellitusHemoglobin a1cGlucose blood level1525-6049